Statistics
| Case | Control |
|---|---|
| 9819 | 450375 |
Phenotype Definition
A type of infection that is regarded as a sign of a pathological susceptibility to infection because of unusual severity or intensity of the infection. []
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:32020512 | rs17207895 | TNXB | T>C | 212 | 13877 | 28.05 | 1.185e-07 | 0.6932 |
| chr7:128764737 | rs77506340 | - | C>T | 2490 | 103386 | 26.57 | 2.543e-07 | 1.118 |
| chr11:22373951 | rs79330667 | SLC17A6 | T>C | 1033 | 40769 | 23.42 | 1.3e-06 | 1.169 |
| chr21:39096139 | rs73206011 | KCNJ6 | C>T | 4779 | 205761 | 22.28 | 2.358e-06 | 1.082 |
| chr1:176567157 | rs78084702 | PAPPA2 | C>A | 700 | 38155 | 21.79 | 3.035e-06 | 0.8345 |
| chr7:13891894 | rs117940565 | - | C>T | 1318 | 53229 | 21.6 | 3.351e-06 | 1.143 |
| chr2:225633209 | rs3754623 | DOCK10 | G>T | 3576 | 175766 | 21.47 | 3.601e-06 | 0.9176 |
| chr3:195838160 | rs77176301 | - | T>C | 517 | 28830 | 20.46 | 6.092e-06 | 0.8164 |
| chr5:162413750 | rs115762882 | - | T>C | 543 | 30157 | 20.46 | 6.077e-06 | 0.8202 |
| chr6:23964399 | rs74705114 | - | C>T | 1659 | 84592 | 20.33 | 6.528e-06 | 0.8901 |
| chr9:108886471 | rs57885798 | - | C>A | 1129 | 58955 | 20.3 | 6.63e-06 | 0.8702 |
| chr12:44292637 | rs35206442 | TMEM117 | G>A | 559 | 21170 | 20.2 | 6.993e-06 | 1.215 |
| chr14:101561195 | rs12879412 | - | G>A | 842 | 32862 | 20.15 | 7.169e-06 | 1.173 |
| chr4:140462426 | rs72726578 | SETD7 | G>C | 3276 | 161255 | 19.75 | 8.837e-06 | 0.9181 |
| chr18:65830606 | rs7243192 | - | A>G | 2587 | 109216 | 19.69 | 9.105e-06 | 1.099 |
| chr20:51762487 | rs77523328 | TSHZ2 | A>C | 908 | 35946 | 19.59 | 9.595e-06 | 1.164 |
| chr1:145420676 | rs79906727 | - | T>C | 1600 | 81505 | 19.53 | 9.906e-06 | 0.8904 |
| chr1:57852910 | rs116777079 | DAB1 | G>C | 251 | 15126 | 18.9 | 1.375e-05 | 0.7577 |
| chr11:83463013 | rs7109065 | DLG2 | T>C | 3103 | 132281 | 18.51 | 1.692e-05 | 1.088 |
| chr20:46032690 | rs60838743 | - | T>C | 885 | 35116 | 18.48 | 1.721e-05 | 1.161 |
| chr6:32020512 | rs17207895 | TNXB | T>C | 207 | 13415 | 25.91 | 3.582e-07 | 0.7 |
| chr11:22373951 | rs79330667 | SLC17A6 | T>C | 1022 | 40231 | 24.48 | 7.504e-07 | 1.174 |
| chr6:23964399 | rs74705114 | - | C>T | 1563 | 80824 | 24.04 | 9.43e-07 | 0.8777 |
| chr1:176567157 | rs78084702 | PAPPA2 | C>A | 683 | 37511 | 22.88 | 1.723e-06 | 0.8288 |
| chr7:128764737 | rs77506340 | - | C>T | 2377 | 99457 | 22.29 | 2.342e-06 | 1.11 |
| chr7:13891894 | rs117940565 | - | C>T | 1294 | 52348 | 21.19 | 4.158e-06 | 1.143 |
| chr21:39096139 | rs73206011 | KCNJ6 | C>T | 4491 | 193677 | 20.33 | 6.52e-06 | 1.081 |
| chr5:162413750 | rs115762882 | - | T>C | 530 | 29518 | 20.29 | 6.656e-06 | 0.8189 |
| chr8:108623555 | rs77148061 | - | C>T | 390 | 14244 | 20.17 | 7.102e-06 | 1.261 |
| chr12:106047204 | rs11112636 | - | G>A | 2601 | 129627 | 19.96 | 7.914e-06 | 0.9094 |
| chr1:57852910 | rs116777079 | DAB1 | G>C | 242 | 14781 | 19.9 | 8.153e-06 | 0.7483 |
| chr4:140462426 | rs72726578 | SETD7 | G>C | 3131 | 154603 | 19.78 | 8.681e-06 | 0.9161 |
| chr13:34985979 | rs9599117 | - | G>C | 512 | 19307 | 19.76 | 8.778e-06 | 1.223 |
| chr16:58032026 | rs56347618 | ZNF319 | G>A | 1093 | 43896 | 19.54 | 9.865e-06 | 1.149 |
| chr9:108886471 | rs57885798 | - | C>A | 982 | 51656 | 19.17 | 1.196e-05 | 0.8654 |
| chr9:80861141 | rs77772506 | CEP78 | C>T | 1840 | 76456 | 19.14 | 1.214e-05 | 1.114 |
| chr6:154800018 | rs12194277 | AL357075.4 | C>T | 9007 | 426689 | 19.01 | 1.302e-05 | 0.938 |
| chr8:77219328 | rs2103225 | - | G>A | 1414 | 57926 | 18.95 | 1.338e-05 | 1.129 |
| chr1:149892872 | rs11205277 | - | A>G | 8842 | 391651 | 18.87 | 1.397e-05 | 1.065 |
| chr5:143181132 | rs79203096 | - | G>A | 276 | 9734 | 18.85 | 1.412e-05 | 1.305 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr7:13891894 | rs117940565 | - | C>T | 1318 | 13011 | 25.33 | 4.829e-07 | 1.162 |
| chr21:39096139 | rs73206011 | KCNJ6 | C>T | 4779 | 50907 | 23.3 | 1.383e-06 | 1.087 |
| chr7:128764737 | rs77506340 | - | C>T | 2490 | 25814 | 21.85 | 2.943e-06 | 1.11 |
| chr20:51762487 | rs77523328 | TSHZ2 | A>C | 908 | 8836 | 20.73 | 5.274e-06 | 1.176 |
| chr11:22373951 | rs79330667 | SLC17A6 | T>C | 1033 | 10163 | 20.56 | 5.774e-06 | 1.164 |
| chr14:101561195 | rs12879412 | - | G>A | 842 | 8108 | 20.33 | 6.525e-06 | 1.181 |
| chr6:32020512 | rs17207895 | TNXB | T>C | 212 | 3287 | 20.14 | 7.209e-06 | 0.7273 |
| chr18:65830606 | rs7243192 | - | A>G | 2587 | 27014 | 19.92 | 8.089e-06 | 1.103 |
| chr12:106047204 | rs11112636 | - | G>A | 2789 | 34419 | 19.71 | 9.005e-06 | 0.9103 |
| chr2:225633209 | rs3754623 | DOCK10 | G>T | 3576 | 43544 | 19.4 | 1.062e-05 | 0.9192 |
| chr12:44292637 | rs35206442 | TMEM117 | G>A | 559 | 5238 | 19.34 | 1.094e-05 | 1.219 |
| chr14:20665538 | rs148846869 | OR11G2 | C>T | 752 | 10044 | 19.06 | 1.269e-05 | 0.8454 |
| chr1:145420676 | rs79906727 | - | T>C | 1600 | 20259 | 19.0 | 1.305e-05 | 0.8889 |
| chr8:108623555 | rs77148061 | - | C>T | 392 | 3544 | 18.94 | 1.351e-05 | 1.263 |
| chr5:162413750 | rs115762882 | - | T>C | 543 | 7464 | 18.86 | 1.407e-05 | 0.8226 |
| chr2:8549862 | rs13390193 | - | T>C | 4381 | 52907 | 18.72 | 1.516e-05 | 0.9262 |
| chr4:1317192 | rs2141656 | MAEA | T>C | 8739 | 102990 | 18.42 | 1.772e-05 | 0.9391 |
| chr14:57489586 | rs7143862 | - | G>A | 4130 | 49826 | 18.27 | 1.916e-05 | 0.9255 |
| chr20:19937312 | rs142502440 | RIN2 | G>A | 687 | 9212 | 18.24 | 1.947e-05 | 0.8423 |
| chr4:140462426 | rs72726578 | SETD7 | G>C | 3276 | 39990 | 18.22 | 1.97e-05 | 0.9189 |
| chr7:13891894 | rs117940565 | - | C>T | 1294 | 12773 | 24.69 | 6.722e-07 | 1.162 |
| chr12:106047204 | rs11112636 | - | G>A | 2601 | 32379 | 23.01 | 1.615e-06 | 0.9003 |
| chr20:19937312 | rs142502440 | RIN2 | G>A | 663 | 9032 | 21.39 | 3.754e-06 | 0.8277 |
| chr8:108623555 | rs77148061 | - | C>T | 390 | 3472 | 21.35 | 3.822e-06 | 1.282 |
| chr11:22373951 | rs79330667 | SLC17A6 | T>C | 1022 | 10025 | 21.0 | 4.602e-06 | 1.167 |
| chr21:39096139 | rs73206011 | KCNJ6 | C>T | 4491 | 47878 | 20.37 | 6.37e-06 | 1.084 |
| chr3:3160512 | rs334797 | IL5RA | A>T | 5390 | 57997 | 19.2 | 1.175e-05 | 1.076 |
| chr20:51762487 | rs77523328 | TSHZ2 | A>C | 861 | 8389 | 19.12 | 1.227e-05 | 1.173 |
| chr1:176567157 | rs78084702 | PAPPA2 | C>A | 683 | 9185 | 19.05 | 1.275e-05 | 0.8386 |
| chr16:58032026 | rs56347618 | ZNF319 | G>A | 1093 | 10840 | 19.03 | 1.286e-05 | 1.153 |
| chr7:128764737 | rs77506340 | - | C>T | 2377 | 24743 | 18.78 | 1.465e-05 | 1.104 |
| chr5:162413750 | rs115762882 | - | T>C | 530 | 7291 | 18.74 | 1.498e-05 | 0.8211 |
| chr6:154800018 | rs12194277 | AL357075.4 | C>T | 9007 | 105690 | 18.71 | 1.524e-05 | 0.9366 |
| chr6:32020512 | rs17207895 | TNXB | T>C | 207 | 3177 | 18.69 | 1.541e-05 | 0.733 |
| chr9:32233829 | rs73644640 | - | G>A | 2095 | 21697 | 18.46 | 1.738e-05 | 1.11 |
| chr14:101561195 | rs12879412 | - | G>A | 819 | 7924 | 18.4 | 1.793e-05 | 1.175 |
| chr16:8232027 | rs1381534 | - | G>T | 1028 | 13351 | 18.38 | 1.811e-05 | 0.8672 |
| chr18:65824781 | rs9952899 | - | A>G | 3968 | 42284 | 18.28 | 1.911e-05 | 1.083 |
| chr4:127629781 | rs41393344 | - | C>T | 313 | 2769 | 17.93 | 2.291e-05 | 1.289 |
| chr14:20665538 | rs148846869 | OR11G2 | C>T | 719 | 9580 | 17.85 | 2.394e-05 | 0.8468 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: B349 | Viral infection, unspecified | 1/20 |
| ICD: J189 | Pneumonia, unspecified | 5/20 |