Statistics
| Case | Control |
|---|---|
| 6415 | 453779 |
Phenotype Definition
An infection that is caused by a fungus that would generally not be able to cause an infection in a host with a normal immune system. Such fungi take advantage of the opportunity, so to speak, that is provided by a weakened immune system. []
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:31369151 | rs2523451 | MICA | G>A | 4849 | 323316 | 25.38 | 4.715e-07 | 1.095 |
| chr5:117745699 | rs75164146 | - | G>A | 559 | 32087 | 25.17 | 5.243e-07 | 1.244 |
| chr2:119474615 | rs114211048 | - | C>A | 427 | 23913 | 23.94 | 9.947e-07 | 1.274 |
| chr6:22611753 | rs6907847 | - | A>G | 245 | 23595 | 23.9 | 1.017e-06 | 0.7293 |
| chr1:37070552 | rs72918759 | - | G>A | 468 | 26610 | 23.11 | 1.531e-06 | 1.256 |
| chr6:106007241 | rs79182871 | - | C>T | 398 | 22375 | 21.18 | 4.179e-06 | 1.266 |
| chr6:31412961 | Affx-28456540 | - | C>T | 6134 | 453914 | 20.65 | 5.513e-06 | 0.924 |
| chr6:31367865 | rs2523454 | MICA | G>A | 4746 | 318686 | 20.52 | 5.915e-06 | 1.086 |
| chr1:240666644 | rs16840259 | GREM2 | T>G | 1424 | 112950 | 20.08 | 7.426e-06 | 0.8814 |
| chr11:105190484 | rs79269987 | CARD18 | G>A | 509 | 43812 | 20.03 | 7.606e-06 | 0.8162 |
| chr23:79509262 | rs4826173 | - | A>G | 2911 | 230172 | 19.88 | 8.245e-06 | 0.906 |
| chr17:71463117 | rs4789644 | SDK2 | C>A | 723 | 43526 | 19.8 | 8.602e-06 | 1.187 |
| chr9:27335339 | rs10967899 | MOB3B | A>G | 5015 | 337813 | 19.69 | 9.127e-06 | 1.083 |
| chr6:31364707 | rs2251396 | - | G>A | 4642 | 311650 | 19.47 | 1.022e-05 | 1.084 |
| chr6:22321910 | rs12189716 | - | G>A | 189 | 9739 | 19.1 | 1.242e-05 | 1.38 |
| chr5:117799448 | rs76528319 | - | T>G | 734 | 44415 | 18.8 | 1.454e-05 | 1.18 |
| chr9:90494280 | rs62578206 | - | T>C | 4049 | 303633 | 18.78 | 1.47e-05 | 0.9214 |
| chr7:100353022 | rs141969527 | ZAN | G>A | 251 | 23277 | 18.59 | 1.617e-05 | 0.7593 |
| chr13:42162573 | rs77738023 | VWA8 | A>G | 714 | 43221 | 18.41 | 1.778e-05 | 1.181 |
| chr23:79698593 | rs1113265 | TENT5D | G>C | 2857 | 225158 | 18.24 | 1.943e-05 | 0.9094 |
| chr2:119474615 | rs114211048 | - | C>A | 422 | 23459 | 24.89 | 6.075e-07 | 1.282 |
| chr5:117745699 | rs75164146 | - | G>A | 542 | 31123 | 24.04 | 9.452e-07 | 1.242 |
| chr6:31369151 | rs2523451 | MICA | G>A | 4670 | 311357 | 23.34 | 1.356e-06 | 1.094 |
| chr9:90494280 | rs62578206 | - | T>C | 3873 | 291382 | 21.2 | 4.138e-06 | 0.9147 |
| chr11:105190484 | rs79269987 | CARD18 | G>A | 497 | 43031 | 21.12 | 4.322e-06 | 0.8097 |
| chr6:31367865 | rs2523454 | MICA | G>A | 4611 | 309184 | 20.13 | 7.246e-06 | 1.087 |
| chr6:106007241 | rs79182871 | - | C>T | 390 | 21984 | 20.0 | 7.739e-06 | 1.26 |
| chr11:105088232 | rs77821781 | CARD18 | G>A | 451 | 39168 | 19.55 | 9.786e-06 | 0.8083 |
| chr7:100353022 | rs141969527 | ZAN | G>A | 246 | 22873 | 18.81 | 1.443e-05 | 0.7559 |
| chr5:10307254 | rs55919919 | CMBL | C>T | 278 | 15198 | 18.59 | 1.624e-05 | 1.301 |
| chr5:117799448 | rs76528319 | - | T>G | 660 | 39578 | 18.53 | 1.671e-05 | 1.189 |
| chr9:8873805 | rs72704342 | PTPRD | T>C | 267 | 14522 | 18.44 | 1.753e-05 | 1.306 |
| chr20:56058239 | rs73182662 | - | A>G | 1695 | 108713 | 18.44 | 1.755e-05 | 1.119 |
| chr8:34678632 | rs78591047 | - | G>C | 757 | 45995 | 18.3 | 1.89e-05 | 1.175 |
| chr2:99767073 | rs139891421 | TSGA10 | G>A | 237 | 12728 | 18.09 | 2.108e-05 | 1.324 |
| chr23:79509262 | rs4826173 | - | A>G | 2552 | 202167 | 18.0 | 2.21e-05 | 0.9058 |
| chr9:27335339 | rs10967899 | MOB3B | A>G | 4693 | 315835 | 17.81 | 2.444e-05 | 1.082 |
| chr8:34236992 | rs2609653 | - | T>C | 886 | 54587 | 17.76 | 2.502e-05 | 1.159 |
| chr6:31412961 | Affx-28456540 | - | C>T | 5716 | 421637 | 17.65 | 2.65e-05 | 0.9275 |
| chr6:31364707 | rs2251396 | - | G>A | 4478 | 300847 | 17.56 | 2.781e-05 | 1.081 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr3:118015581 | rs16828198 | - | T>C | 559 | 508 | 25.62 | 4.151e-07 | 1.37 |
| chr4:62994611 | rs115373922 | - | C>T | 233 | 178 | 23.67 | 1.143e-06 | 1.621 |
| chr12:10880420 | rs117896918 | - | G>A | 268 | 217 | 21.59 | 3.374e-06 | 1.53 |
| chr10:112562342 | rs11195330 | RBM20 | A>G | 4016 | 4545 | 20.53 | 5.877e-06 | 1.125 |
| chr3:28366936 | rs76430272 | AZI2 | G>C | 691 | 671 | 20.17 | 7.103e-06 | 1.283 |
| chr2:149529949 | rs76918096 | EPC2 | G>C | 529 | 500 | 18.7 | 1.528e-05 | 1.315 |
| chr3:42845531 | rs116420319 | AC006059.2 | G>A | 165 | 306 | 18.62 | 1.595e-05 | 0.659 |
| chr9:136519021 | rs3025416 | DBH | C>T | 1976 | 2730 | 18.35 | 1.84e-05 | 0.8709 |
| chr21:46101939 | rs9984476 | TSPEAR | C>T | 1993 | 2744 | 18.18 | 2.009e-05 | 0.8718 |
| chr18:77074487 | rs73003815 | ATP9B | C>A | 177 | 322 | 18.0 | 2.21e-05 | 0.6718 |
| chr21:46105641 | rs2838635 | TSPEAR | C>G | 6003 | 6973 | 18.0 | 2.211e-05 | 1.107 |
| chr9:138271005 | rs62573677 | - | C>T | 2710 | 3668 | 17.95 | 2.262e-05 | 0.8855 |
| chr10:71230112 | rs17569363 | TSPAN15 | A>G | 5754 | 7472 | 17.89 | 2.346e-05 | 0.904 |
| chr12:125321531 | rs10846754 | SCARB1 | G>A | 2663 | 3603 | 17.87 | 2.367e-05 | 0.8851 |
| chr3:132129458 | rs75530476 | - | G>A | 594 | 575 | 17.78 | 2.483e-05 | 1.286 |
| chr23:115358425 | rs12835631 | - | A>G | 373 | 348 | 17.69 | 2.602e-05 | 1.374 |
| chr16:30557392 | rs56311083 | - | C>A | 1472 | 1568 | 17.45 | 2.955e-05 | 1.174 |
| chr14:78360902 | rs56266371 | ADCK1 | A>G | 211 | 170 | 17.4 | 3.023e-05 | 1.537 |
| chr15:40703609 | rs4924466 | IVD | G>A | 841 | 855 | 16.83 | 4.091e-05 | 1.228 |
| chr11:61183554 | rs80264062 | CPSF7 | C>G | 987 | 1018 | 16.81 | 4.127e-05 | 1.209 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|