Cutaneous macular amyloidosis


Normal Case/Contol

GWAS of 0032347

Sibling Case/Control

No sibling GWAS available 0032347


Case Control
191 460003

Phenotype Definition

A type of cutaneous amyloidosis that is characterized by hyperpigmented patches with indefinite margins composed of grayish brown macules, often with a reticulated or rippled appearance. Lesions may present as a hyperpigmented patch composed of small brown macules in a rippled or reticulated pattern. [PMID:26981113]

Phenotype Comment

Two types of keratotic amyloidosis have been identified: macular and lichen amyloidosis, and the latter is more common. In keratotic amyloidosis, keratin depositions originating from basal keratinocyte are mainly CK5 positive.

Top SNP Information

Associated Diseases

ID Name Top Correlation