Statistics
| Case | Control |
|---|---|
| 588 | 459606 |
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr13:64440625 | rs824764 | - | T>C | 114 | 55746 | 26.12 | 3.215e-07 | 1.645 |
| chr10:79959893 | rs55719594 | - | A>G | 291 | 177344 | 25.12 | 5.396e-07 | 1.402 |
| chr19:17256466 | rs17533868 | MYO9B | C>T | 74 | 33381 | 23.31 | 1.376e-06 | 1.772 |
| chr3:18332730 | rs75288358 | TBC1D5 | T>C | 115 | 59123 | 21.48 | 3.57e-06 | 1.569 |
| chr3:45205644 | rs6441893 | - | A>G | 73 | 33541 | 21.41 | 3.703e-06 | 1.736 |
| chr13:30473863 | rs74810548 | - | G>A | 65 | 28827 | 21.18 | 4.174e-06 | 1.784 |
| chr20:5312885 | rs77742798 | - | A>G | 30 | 10373 | 20.94 | 4.733e-06 | 2.278 |
| chr9:1784127 | rs72681779 | - | C>T | 64 | 28562 | 20.6 | 5.65e-06 | 1.777 |
| chr17:26993430 | rs78138983 | SUPT6H | A>G | 41 | 16011 | 20.39 | 6.323e-06 | 2.02 |
| chr4:162083069 | rs75413278 | - | C>T | 39 | 15124 | 20.17 | 7.083e-06 | 2.047 |
| chr12:71016157 | rs74343147 | PTPRB | C>T | 33 | 12026 | 20.03 | 7.634e-06 | 2.163 |
| chr17:25874456 | rs2945387 | KSR1 | A>G | 542 | 361359 | 19.89 | 8.203e-06 | 1.289 |
| chr5:149604397 | rs77905546 | CAMK2A | G>T | 38 | 14669 | 19.88 | 8.237e-06 | 2.054 |
| chr20:15586096 | rs454571 | MACROD2 | A>C | 31 | 11072 | 19.85 | 8.38e-06 | 2.205 |
| chr9:108096748 | rs113909391 | SLC44A1 | A>G | 63 | 28376 | 19.77 | 8.725e-06 | 1.764 |
| chr18:42329076 | rs17783459 | SETBP1 | C>A | 197 | 113876 | 19.77 | 8.753e-06 | 1.41 |
| chr9:29826163 | rs16915329 | - | G>A | 34 | 12598 | 19.63 | 9.382e-06 | 2.124 |
| chr3:45178457 | rs113816614 | CDCP1 | T>G | 70 | 32577 | 19.43 | 1.043e-05 | 1.71 |
| chr4:189150656 | rs6553184 | - | G>A | 525 | 349322 | 19.26 | 1.141e-05 | 1.285 |
| chr5:17043421 | rs114740114 | - | T>C | 52 | 22441 | 19.08 | 1.253e-05 | 1.84 |
| chr20:5312885 | rs77742798 | - | A>G | 30 | 8956 | 30.27 | 3.757e-08 | 2.664 |
| chr10:79959893 | rs55719594 | - | A>G | 282 | 170035 | 26.99 | 2.04e-07 | 1.429 |
| chr13:30473863 | rs74810548 | - | G>A | 65 | 28298 | 23.23 | 1.435e-06 | 1.834 |
| chr4:162083069 | rs75413278 | - | C>T | 39 | 14804 | 21.93 | 2.821e-06 | 2.109 |
| chr18:42329076 | rs17783459 | SETBP1 | C>A | 193 | 110706 | 21.41 | 3.71e-06 | 1.437 |
| chr9:1784127 | rs72681779 | - | C>T | 63 | 27950 | 21.26 | 4.012e-06 | 1.803 |
| chr3:18332730 | rs75288358 | TBC1D5 | T>C | 112 | 57966 | 21.01 | 4.565e-06 | 1.572 |
| chr13:31631135 | rs117183292 | - | G>A | 95 | 47563 | 20.08 | 7.425e-06 | 1.609 |
| chr13:80946323 | rs9669948 | - | A>G | 231 | 232485 | 20.03 | 7.609e-06 | 0.7209 |
| chr17:25874456 | rs2945387 | KSR1 | A>G | 514 | 343877 | 19.79 | 8.625e-06 | 1.298 |
| chr8:95329159 | rs76436483 | - | G>A | 82 | 39868 | 19.56 | 9.763e-06 | 1.651 |
| chr4:43785765 | rs78786285 | - | C>A | 51 | 21808 | 19.55 | 9.794e-06 | 1.866 |
| chr9:8816665 | rs7872026 | PTPRD | C>T | 475 | 314706 | 19.17 | 1.195e-05 | 1.297 |
| chr5:149604397 | rs77905546 | CAMK2A | G>T | 37 | 14455 | 19.09 | 1.244e-05 | 2.045 |
| chr11:59748393 | rs116920273 | OOSP4B | G>T | 54 | 23931 | 18.36 | 1.831e-05 | 1.802 |
| chr20:14353801 | rs6079407 | MACROD2 | G>A | 57 | 25662 | 18.24 | 1.952e-05 | 1.773 |
| chr4:28948442 | rs116435495 | - | C>T | 45 | 18698 | 18.13 | 2.068e-05 | 1.893 |
| chr19:17256466 | rs17533868 | MYO9B | C>T | 67 | 31697 | 18.07 | 2.128e-05 | 1.699 |
| chr3:143425979 | rs73152889 | SLC9A9 | C>T | 228 | 136898 | 18.05 | 2.148e-05 | 1.367 |
| chr18:3284477 | rs1662799 | - | A>T | 373 | 241380 | 17.93 | 2.297e-05 | 1.303 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr3:192055252 | rs4687324 | FGF12 | T>C | 15 | 35 | 21.26 | 4.009e-06 | 0.2607 |
| chr9:93684866 | rs12375897 | - | C>T | 11 | 30 | 20.95 | 4.721e-06 | 0.2245 |
| chr8:125376734 | rs72711187 | TMEM65 | A>G | 2 | 17 | 20.79 | 5.136e-06 | 0.0729 |
| chr18:23361294 | rs7235649 | - | A>G | 363 | 305 | 20.29 | 6.643e-06 | 0.6445 |
| chr7:2028968 | rs34809719 | MAD1L1 | G>T | 259 | 104 | 19.47 | 1.024e-05 | 1.744 |
| chr1:233176596 | rs6424271 | PCNX2 | T>C | 75 | 90 | 19.31 | 1.11e-05 | 0.492 |
| chr19:5857756 | rs55677519 | - | G>A | 219 | 82 | 19.16 | 1.2e-05 | 1.827 |
| chr1:84992110 | rs186360 | SPATA1 | A>G | 616 | 314 | 18.99 | 1.316e-05 | 1.511 |
| chr4:131283821 | rs1022077 | - | T>C | 507 | 242 | 18.87 | 1.399e-05 | 1.531 |
| chr1:216803207 | rs11117635 | ESRRG | C>A | 241 | 216 | 18.56 | 1.65e-05 | 0.628 |
| chr21:18170787 | rs2205285 | - | G>A | 32 | 50 | 18.1 | 2.094e-05 | 0.3856 |
| chr14:26994833 | rs8004600 | NOVA1 | G>T | 170 | 163 | 18.08 | 2.115e-05 | 0.5985 |
| chr20:14353801 | rs6079407 | MACROD2 | G>A | 57 | 9 | 18.0 | 2.207e-05 | 4.137 |
| chr9:2359640 | rs10114018 | - | T>C | 334 | 279 | 17.85 | 2.389e-05 | 0.657 |
| chr16:54861911 | rs76413428 | - | G>A | 87 | 21 | 17.76 | 2.51e-05 | 2.735 |
| chr6:23376983 | rs9366497 | - | G>A | 358 | 295 | 17.67 | 2.631e-05 | 0.6621 |
| chr7:10298689 | rs17162825 | - | A>G | 170 | 60 | 17.6 | 2.73e-05 | 1.925 |
| chr12:29798156 | rs11050338 | TMTC1 | C>T | 327 | 143 | 17.56 | 2.78e-05 | 1.608 |
| chr7:104280259 | rs117315756 | LHFPL3 | A>G | 16 | 33 | 17.46 | 2.935e-05 | 0.2959 |
| chr10:54442734 | rs1000219 | - | G>T | 414 | 330 | 17.2 | 3.369e-05 | 0.672 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: I071 | Tricuspid insufficiency | 9/20 |
| ID | Name | Top Correlation |
|---|