Statistics
| Case | Control |
|---|---|
| 283 | 459911 |
Phenotype Definition
A tumor (abnormal growth of tissue) of the inner ear. [HPO:probinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr18:42371293 | rs74901749 | SETBP1 | G>A | 48 | 37982 | 27.45 | 1.609e-07 | 2.16 |
| chr19:1620536 | rs72989732 | TCF3 | G>A | 68 | 60677 | 27.38 | 1.671e-07 | 1.939 |
| chr15:75276450 | rs75677561 | SCAMP5 | C>T | 61 | 54790 | 23.95 | 9.908e-07 | 1.916 |
| chr6:151123175 | rs9397024 | PLEKHG1 | C>T | 122 | 286997 | 23.41 | 1.306e-06 | 0.6147 |
| chr15:75359949 | rs78166596 | PPCDC | A>G | 45 | 36997 | 23.02 | 1.606e-06 | 2.071 |
| chr16:86069722 | rs4843893 | - | G>A | 35 | 26447 | 22.52 | 2.075e-06 | 2.238 |
| chr12:1684934 | rs7976513 | WNT5B | G>A | 54 | 47549 | 22.39 | 2.229e-06 | 1.941 |
| chr6:101124541 | rs76717114 | ASCC3 | C>T | 37 | 29067 | 22.26 | 2.38e-06 | 2.185 |
| chr1:204189357 | rs61817031 | PLEKHA6 | C>T | 24 | 15668 | 22.21 | 2.449e-06 | 2.578 |
| chr2:79397366 | rs4459759 | - | G>A | 60 | 55379 | 21.55 | 3.45e-06 | 1.863 |
| chr2:9348667 | rs34254156 | ASAP2 | G>A | 221 | 279119 | 21.24 | 4.055e-06 | 1.476 |
| chr3:18022860 | rs11128873 | TBC1D5 | C>T | 24 | 15958 | 21.09 | 4.391e-06 | 2.52 |
| chr4:155163784 | rs138768083 | DCHS2 | TCA>T | 34 | 26047 | 20.99 | 4.619e-06 | 2.201 |
| chr11:95964519 | rs7938889 | MAML2 | T>C | 216 | 450773 | 20.94 | 4.73e-06 | 0.6771 |
| chr12:89460898 | rs117804681 | - | G>A | 19 | 11466 | 20.73 | 5.29e-06 | 2.767 |
| chr10:68600251 | rs77912242 | CTNNA3 | T>C | 56 | 51228 | 20.6 | 5.664e-06 | 1.873 |
| chr4:42115801 | rs75033291 | BEND4 | G>A | 19 | 11544 | 20.42 | 6.217e-06 | 2.748 |
| chr2:96802289 | rs75674705 | ASTL | G>T | 17 | 9813 | 20.33 | 6.514e-06 | 2.887 |
| chr7:107510785 | rs62467989 | - | C>T | 17 | 9887 | 20.17 | 7.094e-06 | 2.876 |
| chr5:180626242 | rs76492548 | TRIM7 | G>A | 61 | 57509 | 20.14 | 7.192e-06 | 1.818 |
| chr19:1620536 | rs72989732 | TCF3 | G>A | 66 | 58362 | 26.75 | 2.319e-07 | 1.945 |
| chr15:75276450 | rs75677561 | SCAMP5 | C>T | 61 | 53927 | 24.7 | 6.704e-07 | 1.938 |
| chr20:46577479 | rs73913246 | - | T>C | 29 | 19503 | 24.39 | 7.857e-07 | 2.486 |
| chr3:24488168 | rs78574410 | THRB | T>C | 18 | 9854 | 23.62 | 1.171e-06 | 3.028 |
| chr6:151123175 | rs9397024 | PLEKHG1 | C>T | 109 | 260879 | 23.53 | 1.229e-06 | 0.5995 |
| chr15:75359949 | rs78166596 | PPCDC | A>G | 45 | 36501 | 23.47 | 1.266e-06 | 2.089 |
| chr18:42371293 | rs74901749 | SETBP1 | G>A | 45 | 36603 | 23.23 | 1.436e-06 | 2.081 |
| chr6:101124541 | rs76717114 | ASCC3 | C>T | 37 | 28487 | 23.13 | 1.512e-06 | 2.22 |
| chr20:41420095 | rs17811401 | PTPRT | T>C | 22 | 13634 | 22.7 | 1.891e-06 | 2.706 |
| chr16:86069722 | rs4843893 | - | G>A | 34 | 25519 | 21.84 | 2.956e-06 | 2.238 |
| chr3:18022860 | rs11128873 | TBC1D5 | C>T | 24 | 15666 | 21.65 | 3.274e-06 | 2.551 |
| chr2:79397366 | rs4459759 | - | G>A | 59 | 53829 | 21.55 | 3.454e-06 | 1.875 |
| chr8:2971378 | rs6558722 | CSMD1 | C>G | 208 | 255290 | 21.12 | 4.325e-06 | 1.497 |
| chr15:75149330 | rs17336243 | SCAMP2 | C>T | 72 | 69809 | 21.07 | 4.427e-06 | 1.771 |
| chr7:107510785 | rs62467989 | - | C>T | 17 | 9654 | 20.89 | 4.876e-06 | 2.928 |
| chr3:114959731 | rs72947771 | - | G>A | 18 | 10641 | 20.72 | 5.303e-06 | 2.842 |
| chr4:42115801 | rs75033291 | BEND4 | G>A | 19 | 11406 | 20.63 | 5.571e-06 | 2.764 |
| chr14:105430886 | rs117572554 | AHNAK2 | C>T | 28 | 19954 | 20.46 | 6.105e-06 | 2.343 |
| chr1:204189357 | rs61817031 | PLEKHA6 | C>T | 23 | 15177 | 20.41 | 6.262e-06 | 2.531 |
| chr1:210732325 | rs4845053 | HHAT | G>C | 26 | 18214 | 19.99 | 7.781e-06 | 2.389 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr19:1620536 | rs72989732 | TCF3 | G>A | 66 | 3562 | 26.76 | 2.309e-07 | 1.956 |
| chr20:41420095 | rs17811401 | PTPRT | T>C | 22 | 772 | 26.22 | 3.045e-07 | 2.935 |
| chr20:46577479 | rs73913246 | - | T>C | 29 | 1167 | 25.28 | 4.955e-07 | 2.549 |
| chr15:75276450 | rs75677561 | SCAMP5 | C>T | 61 | 3319 | 24.01 | 9.577e-07 | 1.931 |
| chr15:75359949 | rs78166596 | PPCDC | A>G | 45 | 2210 | 23.93 | 9.983e-07 | 2.117 |
| chr3:114959731 | rs72947771 | - | G>A | 18 | 621 | 22.46 | 2.149e-06 | 2.994 |
| chr6:151123175 | rs9397024 | PLEKHG1 | C>T | 109 | 15878 | 22.39 | 2.23e-06 | 0.6058 |
| chr3:24488168 | rs78574410 | THRB | T>C | 18 | 613 | 22.34 | 2.284e-06 | 2.984 |
| chr8:2971378 | rs6558722 | CSMD1 | C>G | 208 | 15527 | 22.22 | 2.435e-06 | 1.516 |
| chr16:86069722 | rs4843893 | - | G>A | 34 | 1551 | 21.94 | 2.81e-06 | 2.259 |
| chr15:75149330 | rs17336243 | SCAMP2 | C>T | 72 | 4220 | 21.93 | 2.829e-06 | 1.799 |
| chr18:42371293 | rs74901749 | SETBP1 | G>A | 45 | 2289 | 21.5 | 3.542e-06 | 2.038 |
| chr1:210732325 | rs4845053 | HHAT | G>C | 26 | 1075 | 21.46 | 3.608e-06 | 2.483 |
| chr2:79397366 | rs4459759 | - | G>A | 59 | 3296 | 21.28 | 3.967e-06 | 1.877 |
| chr1:204189357 | rs61817031 | PLEKHA6 | C>T | 23 | 913 | 20.87 | 4.922e-06 | 2.582 |
| chr1:234234578 | rs74196827 | SLC35F3 | G>A | 37 | 1775 | 20.83 | 5.028e-06 | 2.149 |
| chr3:18022860 | rs11128873 | TBC1D5 | C>T | 24 | 981 | 20.16 | 7.139e-06 | 2.498 |
| chr6:90627287 | rs56331762 | GJA10 | A>G | 98 | 6371 | 20.02 | 7.658e-06 | 1.642 |
| chr5:180626242 | rs76492548 | TRIM7 | G>A | 60 | 3427 | 19.9 | 8.168e-06 | 1.831 |
| chr2:9348667 | rs34254156 | ASAP2 | G>A | 213 | 16453 | 19.53 | 9.888e-06 | 1.468 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: F320 | Mild depressive episode | 1/20 |
| ICD: G519 | Disorder of facial nerve, unspecified | 1/20 |
| ID | Name | Top Correlation |
|---|