Statistics
| Case | Control |
|---|---|
| 7984 | 452210 |
Phenotype Definition
An abnormality of the skin of the palm, that is, the skin of the front of the hand. []
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr5:1315660 | rs4975616 | - | A>G | 6757 | 404059 | 26.02 | 3.386e-07 | 0.9223 |
| chr6:28304841 | rs723475 | ZSCAN31 | T>G | 629 | 43653 | 25.09 | 5.463e-07 | 0.8149 |
| chr6:28302884 | rs1416919 | ZSCAN31 | T>G | 631 | 43729 | 24.92 | 5.991e-07 | 0.8157 |
| chr19:8269439 | rs72997309 | - | C>T | 1769 | 89967 | 24.84 | 6.231e-07 | 1.135 |
| chr6:28302113 | rs16893973 | ZSCAN31 | C>T | 631 | 43696 | 24.71 | 6.659e-07 | 0.8164 |
| chr6:28302278 | rs16893975 | ZSCAN31 | T>C | 631 | 43598 | 24.13 | 9.011e-07 | 0.8184 |
| chr21:19126079 | rs7276293 | - | T>C | 380 | 27792 | 24.04 | 9.44e-07 | 0.7746 |
| chr1:17476831 | rs12085482 | - | A>G | 103 | 9445 | 23.86 | 1.034e-06 | 0.6182 |
| chr5:9203914 | rs1805972 | SEMA5A | T>C | 515 | 36159 | 23.05 | 1.582e-06 | 0.8058 |
| chr5:163052317 | rs11949278 | - | T>C | 2294 | 143416 | 22.45 | 2.154e-06 | 0.8983 |
| chr15:98437293 | rs72754617 | - | G>A | 922 | 45098 | 22.39 | 2.229e-06 | 1.176 |
| chr12:76045936 | rs73187040 | - | G>A | 2869 | 151009 | 22.24 | 2.404e-06 | 1.103 |
| chr17:15364293 | rs2875140 | CDRT4 | G>A | 910 | 60388 | 22.02 | 2.698e-06 | 0.8513 |
| chr15:78723082 | rs2656057 | - | C>T | 192 | 15298 | 21.81 | 3.009e-06 | 0.7121 |
| chr5:152564299 | rs17501895 | - | C>T | 6172 | 368803 | 21.73 | 3.134e-06 | 0.9274 |
| chr16:82280093 | rs8051215 | - | T>C | 4772 | 287936 | 21.45 | 3.627e-06 | 0.9231 |
| chr8:78735245 | rs13249086 | - | C>T | 1251 | 62848 | 21.07 | 4.438e-06 | 1.146 |
| chr3:111515326 | rs58651217 | PLCXD2 | C>A | 358 | 25945 | 21.04 | 4.502e-06 | 0.7818 |
| chr6:28264681 | rs3800324 | PGBD1 | G>A | 649 | 44138 | 20.84 | 4.996e-06 | 0.8321 |
| chr6:28294888 | rs4711167 | ZSCAN31 | T>C | 654 | 44413 | 20.73 | 5.301e-06 | 0.833 |
| chr5:1315660 | rs4975616 | - | A>G | 6412 | 380814 | 24.54 | 7.291e-07 | 0.9225 |
| chr12:76045936 | rs73187040 | - | G>A | 2801 | 146346 | 22.28 | 2.36e-06 | 1.104 |
| chr12:58766772 | rs112106612 | - | C>T | 455 | 20803 | 21.17 | 4.208e-06 | 1.247 |
| chr2:2228745 | rs17247281 | MYT1L | C>G | 766 | 36966 | 20.18 | 7.066e-06 | 1.183 |
| chr5:24867580 | rs1353064 | - | C>T | 2799 | 146815 | 19.77 | 8.745e-06 | 1.098 |
| chr1:173190901 | rs115292553 | - | G>A | 230 | 9723 | 19.63 | 9.403e-06 | 1.345 |
| chr12:12031894 | rs2855712 | ETV6 | G>C | 5842 | 346387 | 19.58 | 9.652e-06 | 0.9292 |
| chr21:29495371 | rs75753005 | - | G>C | 524 | 24541 | 19.37 | 1.076e-05 | 1.218 |
| chr15:98437293 | rs72754617 | - | G>A | 893 | 43774 | 19.25 | 1.146e-05 | 1.165 |
| chr18:60004253 | rs7237982 | TNFRSF11A | A>G | 3999 | 213245 | 19.21 | 1.174e-05 | 1.084 |
| chr6:28302884 | rs1416919 | ZSCAN31 | T>G | 533 | 36362 | 19.03 | 1.286e-05 | 0.8242 |
| chr6:28302113 | rs16893973 | ZSCAN31 | C>T | 533 | 36331 | 18.88 | 1.394e-05 | 0.8249 |
| chr3:93965012 | rs66877608 | - | G>C | 1709 | 106614 | 18.87 | 1.397e-05 | 0.8939 |
| chr5:1322087 | rs401681 | CLPTM1L | C>T | 6725 | 396773 | 18.87 | 1.398e-05 | 0.9321 |
| chr19:8269439 | rs72997309 | - | C>T | 1692 | 86592 | 18.69 | 1.538e-05 | 1.119 |
| chr6:80965108 | rs117964117 | BCKDHB | T>C | 657 | 43926 | 18.67 | 1.552e-05 | 0.8408 |
| chr6:28304841 | rs723475 | ZSCAN31 | T>G | 533 | 36292 | 18.58 | 1.631e-05 | 0.8261 |
| chr19:52973262 | rs1112889 | ZNF578 | A>G | 602 | 28661 | 18.53 | 1.676e-05 | 1.198 |
| chr18:73494104 | rs17224239 | - | C>T | 2098 | 108683 | 18.52 | 1.679e-05 | 1.107 |
| chr1:212913168 | rs2271148 | NSL1 | T>C | 1385 | 70200 | 18.44 | 1.753e-05 | 1.13 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:31242731 | rs12199223 | HLA-B | T>A | 1416 | 2601 | 56.72 | 5.026e-14 | 0.7698 |
| chr6:31289714 | rs28894993 | HLA-B | G>T | 1485 | 2713 | 54.98 | 1.22e-13 | 0.7772 |
| chr6:31251924 | rs12189871 | HLA-B | C>T | 1475 | 2690 | 53.97 | 2.031e-13 | 0.7784 |
| chr6:31316699 | rs28732138 | HLA-B | G>A | 1473 | 2681 | 53.58 | 2.478e-13 | 0.7789 |
| chr6:31087060 | rs13201757 | PSORS1C1 | C>T | 1656 | 2919 | 43.47 | 4.302e-11 | 0.8066 |
| chr6:31090078 | rs6913137 | PSORS1C1 | T>G | 1680 | 2951 | 42.15 | 8.468e-11 | 0.8102 |
| chr6:31094120 | rs3778640 | PSORS1C1 | G>C | 1592 | 2811 | 41.94 | 9.407e-11 | 0.8067 |
| chr6:31095003 | rs6931921 | PSORS1C1 | G>C | 1558 | 2754 | 41.41 | 1.233e-10 | 0.8062 |
| chr6:31093190 | rs6909321 | PSORS1C1 | G>A | 1587 | 2801 | 41.39 | 1.248e-10 | 0.8076 |
| chr6:31094803 | rs17196961 | PSORS1C1 | G>T | 1593 | 2797 | 39.74 | 2.908e-10 | 0.8113 |
| chr6:31004521 | rs28732082 | - | G>A | 1020 | 1871 | 37.93 | 7.332e-10 | 0.7803 |
| chr6:31001177 | rs28732080 | MUC22 | T>C | 944 | 1748 | 37.75 | 8.022e-10 | 0.7741 |
| chr6:31001143 | rs13210132 | MUC22 | A>G | 944 | 1748 | 37.68 | 8.354e-10 | 0.7743 |
| chr6:31274555 | rs10484554 | HLA-B | C>T | 1991 | 3406 | 37.29 | 1.016e-09 | 0.8312 |
| chr6:31244082 | rs13203895 | HLA-B | C>T | 1991 | 3404 | 37.22 | 1.053e-09 | 0.8314 |
| chr15:50785016 | rs148783236 | USP8 | A>G | 1993 | 3405 | 36.7 | 1.38e-09 | 0.8325 |
| chr6:31236201 | rs12207404 | - | G>A | 1901 | 3262 | 36.69 | 1.383e-09 | 0.8292 |
| chr6:31252925 | rs12191877 | HLA-B | C>T | 1960 | 3351 | 36.66 | 1.406e-09 | 0.8315 |
| chr6:31003701 | rs28894977 | - | T>C | 1015 | 1848 | 36.59 | 1.46e-09 | 0.783 |
| chr6:31245534 | rs10456057 | HLA-B | A>G | 1985 | 3385 | 35.89 | 2.084e-09 | 0.8339 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: L720 | Epidermal cyst | 1/20 |