Statistics
| Case | Control |
|---|---|
| 8661 | 451533 |
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr5:33951693 | rs16891982 | SLC45A2 | G>C | 844 | 66214 | 132.2 | 1.321e-30 | 0.6667 |
| chr18:46453463 | rs4939827 | SMAD7 | T>C | 7989 | 468114 | 125.4 | 4.202e-29 | 0.8437 |
| chr15:48426484 | rs1426654 | SLC24A5 | A>G | 261 | 27265 | 123.4 | 1.154e-28 | 0.5053 |
| chr15:48392165 | rs1834640 | - | A>G | 344 | 31280 | 101.1 | 8.915e-24 | 0.5806 |
| chr5:33958959 | rs28777 | SLC45A2 | A>C | 733 | 56259 | 100.8 | 1.024e-23 | 0.6846 |
| chr1:159174683 | rs2814778 | ACKR1 | T>C | 178 | 19199 | 91.96 | 8.859e-22 | 0.4913 |
| chr8:10557760 | rs57041981 | RP1L1 | A>G | 148 | 16500 | 84.04 | 4.86e-20 | 0.4757 |
| chr6:3185712 | rs7754077 | - | C>T | 177 | 18495 | 82.99 | 8.242e-20 | 0.5074 |
| chr14:75011541 | rs934997 | LTBP2 | A>G | 163 | 17493 | 82.85 | 8.861e-20 | 0.4942 |
| chr11:111125512 | rs2001754 | C11orf53 | A>G | 6469 | 316179 | 80.42 | 3.026e-19 | 1.151 |
| chr6:100241479 | rs9495569 | - | A>G | 238 | 22465 | 79.46 | 4.924e-19 | 0.5617 |
| chr16:29035406 | rs74014848 | - | A>G | 224 | 21257 | 76.24 | 2.516e-18 | 0.5588 |
| chr12:3417813 | rs729914 | - | G>T | 148 | 15939 | 75.73 | 3.259e-18 | 0.4932 |
| chr8:145639681 | rs1871534 | SLC39A4 | G>C | 178 | 17967 | 75.0 | 4.716e-18 | 0.525 |
| chr5:33951116 | rs35397 | SLC45A2 | T>G | 1321 | 88787 | 74.83 | 5.14e-18 | 0.7799 |
| chr15:45491394 | rs1648299 | SHF | T>C | 164 | 16995 | 74.8 | 5.204e-18 | 0.5121 |
| chr11:111171709 | rs3802842 | COLCA2 | A>C | 5908 | 287789 | 73.57 | 9.696e-18 | 1.147 |
| chr2:66725070 | rs12995572 | MEIS1 | G>C | 311 | 26840 | 73.52 | 9.959e-18 | 0.6135 |
| chr17:29290106 | rs55861543 | - | C>T | 218 | 20541 | 72.28 | 1.863e-17 | 0.563 |
| chr16:129223 | rs710079 | MPG | C>T | 326 | 27716 | 72.17 | 1.971e-17 | 0.623 |
| chr18:46453463 | rs4939827 | SMAD7 | T>C | 7620 | 431058 | 95.87 | 1.229e-22 | 0.8595 |
| chr11:111171709 | rs3802842 | COLCA2 | A>C | 5722 | 272421 | 65.82 | 4.951e-16 | 1.141 |
| chr11:111165009 | rs7103178 | - | T>C | 5733 | 273060 | 65.39 | 6.157e-16 | 1.141 |
| chr8:128413305 | rs6983267 | POU5F1B | G>T | 7826 | 434935 | 61.19 | 5.172e-15 | 0.8865 |
| chr15:33022090 | rs35330276 | GREM1 | G>A | 3618 | 167604 | 60.83 | 6.218e-15 | 1.159 |
| chr15:32994756 | rs4779584 | - | C>T | 3675 | 170500 | 60.22 | 8.479e-15 | 1.157 |
| chr11:111125512 | rs2001754 | C11orf53 | A>G | 6317 | 304863 | 57.04 | 4.276e-14 | 1.128 |
| chr8:128407443 | rs10505477 | POU5F1B | A>G | 8002 | 443030 | 56.91 | 4.565e-14 | 0.8904 |
| chr20:60968596 | rs1570027 | CABLES2 | A>G | 3515 | 204241 | 52.87 | 3.561e-13 | 0.8706 |
| chr8:117630683 | rs16892766 | - | A>C | 1618 | 71494 | 47.04 | 6.958e-12 | 1.198 |
| chr18:46453754 | rs35352860 | SMAD7 | C>T | 4239 | 241284 | 45.26 | 1.722e-11 | 0.887 |
| chr8:128428638 | Affx-31548678 | POU5F1B | G>A | 6627 | 367869 | 42.42 | 7.367e-11 | 0.902 |
| chr15:33066195 | rs75798403 | FMN1 | C>A | 2539 | 117230 | 42.33 | 7.706e-11 | 1.152 |
| chr20:60920700 | rs6143035 | LAMA5 | T>C | 3901 | 222674 | 41.8 | 1.01e-10 | 0.8881 |
| chr8:117640315 | rs11986063 | - | C>T | 1751 | 78635 | 41.57 | 1.136e-10 | 1.178 |
| chr20:60921044 | rs4925386 | LAMA5 | C>T | 5079 | 284990 | 39.99 | 2.549e-10 | 0.899 |
| chr20:60958651 | rs11699160 | - | T>C | 5777 | 321841 | 39.19 | 3.854e-10 | 0.9031 |
| chr8:128424792 | rs7014346 | POU5F1B | G>A | 6830 | 336161 | 35.72 | 2.278e-09 | 1.098 |
| chr8:128428795 | Affx-31548681 | POU5F1B | A>G | 8969 | 446764 | 34.88 | 3.514e-09 | 1.095 |
| chr15:32992658 | rs28399071 | - | G>A | 1841 | 84250 | 33.67 | 6.523e-09 | 1.155 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr2:45449038 | rs10192473 | - | C>T | 2232 | 5051 | 22.74 | 1.852e-06 | 1.138 |
| chr13:26536373 | rs116573394 | ATP8A2 | A>C | 962 | 2889 | 22.26 | 2.378e-06 | 0.8346 |
| chr25:2487317 | rs4892816 | - | T>C | 331 | 1119 | 21.8 | 3.031e-06 | 0.7452 |
| chr10:24634956 | rs2484873 | KIAA1217 | G>A | 944 | 2001 | 21.76 | 3.097e-06 | 1.208 |
| chr9:20982515 | rs56069924 | FOCAD | G>C | 479 | 1542 | 21.67 | 3.24e-06 | 0.7815 |
| chr8:128413305 | rs6983267 | POU5F1B | G>T | 7826 | 20742 | 20.99 | 4.623e-06 | 0.9208 |
| chr12:30149270 | rs61924791 | - | C>T | 1232 | 2684 | 20.91 | 4.817e-06 | 1.177 |
| chr3:4628541 | rs4685771 | ITPR1 | C>T | 1279 | 3736 | 20.71 | 5.346e-06 | 0.8579 |
| chr9:20907871 | rs79938787 | FOCAD | G>A | 652 | 2019 | 20.61 | 5.627e-06 | 0.8119 |
| chr8:128407443 | rs10505477 | POU5F1B | A>G | 8002 | 21175 | 20.47 | 6.066e-06 | 0.9218 |
| chr3:4609210 | rs17040924 | ITPR1 | C>T | 492 | 1565 | 19.92 | 8.079e-06 | 0.7916 |
| chr13:81420012 | rs56352522 | - | T>C | 887 | 1893 | 18.82 | 1.435e-05 | 1.198 |
| chr10:62247057 | rs10761509 | ANK3 | C>T | 7559 | 18320 | 18.8 | 1.452e-05 | 1.082 |
| chr13:81309413 | rs7339155 | - | A>C | 918 | 1967 | 18.78 | 1.469e-05 | 1.194 |
| chr10:135339508 | rs6413423 | CYP2E1 | T>G | 264 | 903 | 18.73 | 1.502e-05 | 0.7377 |
| chr6:155746743 | rs117983021 | NOX3 | C>T | 424 | 835 | 18.44 | 1.75e-05 | 1.295 |
| chr25:1467404 | rs17879004 | - | A>C | 1600 | 4562 | 18.28 | 1.908e-05 | 0.8776 |
| chr12:86293828 | rs116965669 | - | A>C | 305 | 1017 | 17.93 | 2.296e-05 | 0.7571 |
| chr7:55128339 | rs1024748 | EGFR | T>G | 3424 | 8037 | 17.9 | 2.327e-05 | 1.101 |
| chr8:15875132 | rs56337232 | - | T>C | 235 | 811 | 17.84 | 2.405e-05 | 0.7305 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: D126 | Colon, unspecified | 9/20 |
| ICD: D128 | Rectum | 10/20 |
| ID | Name | Top Correlation |
|---|---|---|
| ICD-10: C189 | Colon, unspecified | 0/20 |
| ICD-10: C796 | Secondary malignant neoplasm of ovary | 0/20 |
| ICD-10: D374 | Colon | 0/20 |
| ICD-10: D375 | Rectum | 0/20 |