Statistics
| Case | Control |
|---|---|
| 3392 | 456802 |
Phenotype Definition
A problem occurring during any phase of the male sexual response cycle that prevents the individual from experiencing satisfaction from the sexual activity [PMID:29532805]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr16:65762809 | rs4436778 | - | T>C | 249 | 24233 | 25.33 | 4.83e-07 | 1.384 |
| chr5:12383942 | rs7712169 | - | G>A | 230 | 22616 | 21.78 | 3.062e-06 | 1.368 |
| chr5:125371267 | rs3909300 | - | A>G | 1115 | 168532 | 21.07 | 4.421e-06 | 0.8606 |
| chr5:12121629 | rs72731063 | - | C>T | 222 | 21888 | 20.73 | 5.292e-06 | 1.364 |
| chr4:141001765 | rs114528260 | MAML3 | A>C | 426 | 45838 | 20.53 | 5.881e-06 | 1.255 |
| chr19:52376207 | rs9807842 | ZNF577 | G>A | 241 | 24163 | 20.03 | 7.623e-06 | 1.341 |
| chr23:142128914 | rs5908519 | - | A>G | 674 | 89860 | 19.58 | 9.652e-06 | 1.202 |
| chr19:52376126 | rs10407547 | ZNF577 | C>T | 240 | 24142 | 19.55 | 9.779e-06 | 1.337 |
| chr10:65593561 | rs2140390 | - | G>T | 1700 | 205962 | 19.47 | 1.021e-05 | 1.131 |
| chr7:10089086 | rs10257866 | - | G>A | 262 | 26707 | 19.41 | 1.053e-05 | 1.32 |
| chr20:7162079 | rs6054787 | - | G>A | 204 | 20102 | 19.13 | 1.22e-05 | 1.365 |
| chr5:17316288 | rs16869690 | - | A>G | 616 | 69304 | 19.0 | 1.306e-05 | 1.202 |
| chr20:7127831 | rs6054767 | - | C>G | 186 | 18094 | 18.82 | 1.435e-05 | 1.381 |
| chr18:45010992 | rs75982555 | - | G>A | 664 | 75313 | 18.8 | 1.455e-05 | 1.194 |
| chr2:170998316 | rs7563171 | - | C>A | 1644 | 199520 | 18.69 | 1.542e-05 | 1.129 |
| chr7:37940969 | rs7798083 | EPDR1 | T>C | 270 | 27814 | 18.61 | 1.606e-05 | 1.307 |
| chr5:41503149 | rs628092 | PLCXD3 | A>G | 594 | 66803 | 18.36 | 1.826e-05 | 1.202 |
| chr2:29387990 | rs3112921 | CLIP4 | A>G | 579 | 64895 | 18.32 | 1.866e-05 | 1.204 |
| chr5:39505889 | rs268092 | - | G>A | 200 | 19781 | 18.03 | 2.174e-05 | 1.356 |
| chr3:117084425 | rs2869782 | - | C>T | 452 | 49635 | 18.0 | 2.205e-05 | 1.23 |
| chr16:547297 | rs2301487 | RAB11FIP3 | T>C | 309 | 31893 | 22.48 | 2.119e-06 | 1.319 |
| chr10:65593561 | rs2140390 | - | G>T | 1631 | 198117 | 21.67 | 3.241e-06 | 1.142 |
| chr4:141001765 | rs114528260 | MAML3 | A>C | 415 | 44755 | 21.43 | 3.673e-06 | 1.265 |
| chr18:45010992 | rs75982555 | - | G>A | 625 | 71064 | 19.29 | 1.123e-05 | 1.203 |
| chr3:186953932 | rs72549154 | MASP1 | C>A | 302 | 31727 | 19.23 | 1.161e-05 | 1.295 |
| chr8:4952726 | rs76434540 | - | T>C | 122 | 24137 | 19.04 | 1.281e-05 | 0.6723 |
| chr23:154395148 | rs113038688 | - | C>T | 161 | 18195 | 18.99 | 1.317e-05 | 1.418 |
| chr8:40212182 | rs16889217 | - | T>C | 695 | 109292 | 18.63 | 1.591e-05 | 0.841 |
| chr5:125371267 | rs3909300 | - | A>G | 1058 | 160433 | 18.21 | 1.981e-05 | 0.8663 |
| chr22:34583078 | rs5999246 | - | G>A | 1149 | 173365 | 18.11 | 2.086e-05 | 0.8709 |
| chr22:34571858 | rs1489874 | - | A>G | 1215 | 182696 | 18.03 | 2.17e-05 | 0.8738 |
| chr19:12699336 | rs74636691 | ZNF490 | C>T | 430 | 47557 | 17.61 | 2.717e-05 | 1.233 |
| chr6:89926962 | rs1186902 | GABRR1 | T>C | 1921 | 238336 | 17.55 | 2.792e-05 | 1.12 |
| chr23:40450585 | rs9014 | ATP6AP2 | C>G | 428 | 55751 | 17.46 | 2.927e-05 | 1.237 |
| chr21:30882269 | rs112999462 | BACH1 | T>C | 261 | 27220 | 17.37 | 3.075e-05 | 1.302 |
| chr14:49974758 | rs76287881 | - | T>G | 195 | 19568 | 17.34 | 3.12e-05 | 1.354 |
| chr1:67165016 | rs17492406 | SGIP1 | C>T | 242 | 25036 | 17.26 | 3.259e-05 | 1.313 |
| chr1:179054692 | rs912758 | TOR3A | G>T | 2710 | 342627 | 17.14 | 3.479e-05 | 1.109 |
| chr14:82825294 | Affx-11008074 | - | G>T | 2699 | 341738 | 17.08 | 3.581e-05 | 1.109 |
| chr22:34620754 | rs753600 | - | C>T | 1057 | 159610 | 16.9 | 3.934e-05 | 0.8711 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr5:176165781 | rs74648291 | - | C>T | 421 | 1987 | 23.41 | 1.306e-06 | 1.306 |
| chr10:65593561 | rs2140390 | - | G>T | 1631 | 8850 | 21.8 | 3.024e-06 | 1.155 |
| chr19:12699336 | rs74636691 | ZNF490 | C>T | 430 | 2057 | 21.55 | 3.451e-06 | 1.288 |
| chr8:40212182 | rs16889217 | - | T>C | 695 | 4994 | 19.46 | 1.028e-05 | 0.8282 |
| chr4:141001765 | rs114528260 | MAML3 | A>C | 415 | 2004 | 19.06 | 1.268e-05 | 1.274 |
| chr2:138347431 | rs77701389 | THSD7B | G>T | 655 | 3322 | 18.99 | 1.312e-05 | 1.216 |
| chr5:12121629 | rs72731063 | - | C>T | 179 | 762 | 18.86 | 1.406e-05 | 1.438 |
| chr6:89926962 | rs1186902 | GABRR1 | T>C | 1921 | 10650 | 18.52 | 1.684e-05 | 1.134 |
| chr11:108368145 | rs56393920 | POGLUT3 | A>C | 1255 | 6757 | 18.42 | 1.776e-05 | 1.157 |
| chr3:186953932 | rs72549154 | MASP1 | C>A | 302 | 1409 | 18.01 | 2.199e-05 | 1.316 |
| chr10:22581581 | rs116940348 | - | G>A | 183 | 1535 | 17.96 | 2.253e-05 | 0.7155 |
| chr11:103349922 | rs144717489 | DYNC2H1 | G>C | 133 | 540 | 17.76 | 2.504e-05 | 1.505 |
| chr19:2610822 | rs8104096 | GNG7 | C>T | 1675 | 11172 | 17.64 | 2.672e-05 | 0.8807 |
| chr2:193640441 | rs17698772 | - | A>G | 177 | 1488 | 17.52 | 2.849e-05 | 0.7147 |
| chr2:134611730 | Affx-17867364 | - | G>T | 2449 | 15967 | 17.48 | 2.909e-05 | 0.8924 |
| chr9:14219691 | rs7048086 | NFIB | C>T | 119 | 474 | 17.46 | 2.931e-05 | 1.535 |
| chr20:5873431 | rs1287077 | - | G>C | 1860 | 12307 | 17.27 | 3.24e-05 | 0.8855 |
| chr3:54884622 | rs73063754 | CACNA2D3 | A>G | 133 | 543 | 17.17 | 3.41e-05 | 1.495 |
| chr17:14808988 | rs16950572 | - | T>C | 1904 | 10583 | 16.88 | 3.975e-05 | 1.128 |
| chr23:14301348 | rs148720499 | - | G>A | 192 | 722 | 16.87 | 4.001e-05 | 1.404 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: N484 | Impotence of organic origin | 1/20 |
| ICD: R208 | Other and unspecified disturbances of skin sensation | 6/20 |