Statistics
| Case | Control |
|---|---|
| 6759 | 453435 |
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr14:94844947 | rs28929474 | SERPINA1 | C>T | 378 | 17970 | 46.64 | 8.546e-12 | 1.43 |
| chr6:31322980 | rs1131500 | HLA-B | C>T | 4070 | 296709 | 36.52 | 1.508e-09 | 0.8931 |
| chr6:31322911 | Affx-28452375 | HLA-B | C>T | 4059 | 295420 | 34.37 | 4.562e-09 | 0.8963 |
| chr14:94838142 | rs112635299 | - | G>T | 368 | 18596 | 30.87 | 2.765e-08 | 1.343 |
| chr15:78857939 | rs55853698 | CHRNA5 | T>G | 4943 | 312467 | 30.39 | 3.533e-08 | 1.103 |
| chr15:78857986 | rs55781567 | CHRNA5 | C>G | 5003 | 316312 | 30.37 | 3.563e-08 | 1.102 |
| chr15:78894339 | rs1051730 | CHRNA3 | G>A | 4899 | 309243 | 29.91 | 4.524e-08 | 1.102 |
| chr15:78878541 | rs951266 | CHRNA5 | G>A | 4884 | 308692 | 29.39 | 5.904e-08 | 1.101 |
| chr15:78868636 | rs72740964 | CHRNA5 | G>A | 4821 | 304454 | 29.39 | 5.929e-08 | 1.102 |
| chr15:78806023 | rs8034191 | HYKK | T>C | 4971 | 314446 | 29.0 | 7.242e-08 | 1.1 |
| chr15:78814046 | rs10519203 | HYKK | A>G | 5043 | 319366 | 28.58 | 9.003e-08 | 1.099 |
| chr15:78882925 | rs16969968 | CHRNA5 | G>A | 4875 | 308514 | 27.59 | 1.496e-07 | 1.098 |
| chr15:78873993 | rs7180002 | CHRNA5 | A>T | 4881 | 308607 | 27.58 | 1.505e-07 | 1.098 |
| chr15:78896129 | rs1317286 | CHRNA3 | A>G | 4968 | 315119 | 27.06 | 1.967e-07 | 1.096 |
| chr15:78802869 | rs9788721 | HYKK | T>C | 5124 | 325485 | 27.05 | 1.98e-07 | 1.096 |
| chr15:78867482 | rs17486278 | CHRNA5 | A>C | 4963 | 314955 | 26.92 | 2.12e-07 | 1.096 |
| chr15:78783277 | rs11858836 | IREB2 | G>A | 4698 | 297697 | 26.66 | 2.424e-07 | 1.097 |
| chr6:50608564 | rs9357665 | - | C>T | 3940 | 247370 | 26.36 | 2.841e-07 | 1.102 |
| chr15:78911672 | rs4243084 | CHRNA3 | G>C | 5002 | 317708 | 26.13 | 3.189e-07 | 1.095 |
| chr15:78826180 | rs931794 | HYKK | A>G | 5022 | 319006 | 26.01 | 3.401e-07 | 1.094 |
| chr14:94844947 | rs28929474 | SERPINA1 | C>T | 378 | 17814 | 47.74 | 4.86e-12 | 1.437 |
| chr14:94838142 | rs112635299 | - | G>T | 368 | 18418 | 31.98 | 1.559e-08 | 1.351 |
| chr15:78857939 | rs55853698 | CHRNA5 | T>G | 4809 | 302634 | 29.72 | 4.98e-08 | 1.104 |
| chr15:78868636 | rs72740964 | CHRNA5 | G>A | 4698 | 295168 | 29.31 | 6.181e-08 | 1.104 |
| chr15:78894339 | rs1051730 | CHRNA3 | G>A | 4754 | 298826 | 28.94 | 7.446e-08 | 1.103 |
| chr15:78878541 | rs951266 | CHRNA5 | G>A | 4741 | 298331 | 28.52 | 9.262e-08 | 1.102 |
| chr15:78802869 | rs9788721 | HYKK | T>C | 4880 | 307697 | 28.03 | 1.196e-07 | 1.1 |
| chr15:78867482 | rs17486278 | CHRNA5 | A>C | 4752 | 299469 | 27.91 | 1.27e-07 | 1.101 |
| chr15:78826180 | rs931794 | HYKK | A>G | 4821 | 303868 | 27.89 | 1.285e-07 | 1.1 |
| chr6:31322980 | rs1131500 | HLA-B | C>T | 3691 | 266356 | 27.86 | 1.305e-07 | 0.9022 |
| chr15:78911672 | rs4243084 | CHRNA3 | G>C | 4822 | 304051 | 27.57 | 1.511e-07 | 1.1 |
| chr15:78857986 | rs55781567 | CHRNA5 | C>G | 4799 | 302576 | 27.56 | 1.524e-07 | 1.1 |
| chr15:78882925 | rs16969968 | CHRNA5 | G>A | 4750 | 299194 | 27.32 | 1.727e-07 | 1.1 |
| chr15:78806023 | rs8034191 | HYKK | T>C | 4802 | 302727 | 27.14 | 1.891e-07 | 1.099 |
| chr15:78873993 | rs7180002 | CHRNA5 | A>T | 4739 | 298246 | 26.89 | 2.153e-07 | 1.099 |
| chr15:78896129 | rs1317286 | CHRNA3 | A>G | 4779 | 301504 | 26.74 | 2.326e-07 | 1.098 |
| chr6:31322911 | Affx-28452375 | HLA-B | C>T | 3685 | 265487 | 26.4 | 2.774e-07 | 0.9049 |
| chr15:78898723 | rs12914385 | CHRNA3 | C>T | 5442 | 345411 | 26.36 | 2.835e-07 | 1.095 |
| chr15:78783277 | rs11858836 | IREB2 | G>A | 4579 | 288787 | 26.34 | 2.86e-07 | 1.099 |
| chr15:78814046 | rs10519203 | HYKK | A>G | 4816 | 304132 | 25.88 | 3.625e-07 | 1.096 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr14:94844947 | rs28929474 | SERPINA1 | C>T | 378 | 14114 | 47.96 | 4.347e-12 | 1.439 |
| chr14:94838142 | rs112635299 | - | G>T | 368 | 14600 | 32.09 | 1.474e-08 | 1.353 |
| chr15:78857939 | rs55853698 | CHRNA5 | T>G | 4809 | 240029 | 30.27 | 3.751e-08 | 1.105 |
| chr15:78868636 | rs72740964 | CHRNA5 | G>A | 4698 | 234113 | 29.85 | 4.67e-08 | 1.105 |
| chr15:78894339 | rs1051730 | CHRNA3 | G>A | 4754 | 236999 | 29.54 | 5.482e-08 | 1.104 |
| chr15:78878541 | rs951266 | CHRNA5 | G>A | 4741 | 236636 | 28.99 | 7.27e-08 | 1.103 |
| chr15:78867482 | rs17486278 | CHRNA5 | A>C | 4752 | 237499 | 28.48 | 9.472e-08 | 1.102 |
| chr15:78911672 | rs4243084 | CHRNA3 | G>C | 4822 | 241060 | 28.41 | 9.806e-08 | 1.101 |
| chr15:78826180 | rs931794 | HYKK | A>G | 4821 | 241010 | 28.37 | 1.003e-07 | 1.101 |
| chr15:78802869 | rs9788721 | HYKK | T>C | 4880 | 244153 | 28.16 | 1.114e-07 | 1.101 |
| chr6:31322980 | rs1131500 | HLA-B | C>T | 3691 | 211450 | 28.11 | 1.146e-07 | 0.9017 |
| chr15:78857986 | rs55781567 | CHRNA5 | C>G | 4799 | 239979 | 28.11 | 1.148e-07 | 1.101 |
| chr15:78882925 | rs16969968 | CHRNA5 | G>A | 4750 | 237283 | 27.89 | 1.283e-07 | 1.101 |
| chr15:78806023 | rs8034191 | HYKK | T>C | 4802 | 240162 | 27.44 | 1.62e-07 | 1.1 |
| chr15:78873993 | rs7180002 | CHRNA5 | A>T | 4739 | 236550 | 27.41 | 1.647e-07 | 1.1 |
| chr15:78896129 | rs1317286 | CHRNA3 | A>G | 4779 | 239121 | 27.31 | 1.736e-07 | 1.1 |
| chr15:78898723 | rs12914385 | CHRNA3 | C>T | 5442 | 273949 | 26.94 | 2.103e-07 | 1.096 |
| chr6:31322911 | Affx-28452375 | HLA-B | C>T | 3685 | 210813 | 26.65 | 2.44e-07 | 0.9043 |
| chr15:78911181 | rs8040868 | CHRNA3 | T>C | 5583 | 281714 | 26.26 | 2.986e-07 | 1.095 |
| chr15:78814046 | rs10519203 | HYKK | A>G | 4816 | 241270 | 26.19 | 3.089e-07 | 1.097 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: J439 | Emphysema, unspecified | 17/20 |