Neoplasm of the central nervous system

0100006

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Sex Split

Interactive Plot

Statistics

Case	Control
16788	443406

Phenotype Definition

A neoplasm of the central nervous system. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr22:19327744	rs1210701	HIRA	G>A	1985	45679	34.05	5.374e-09	1.147
chr22:19309389	rs9604954	-	G>A	1981	45623	33.2	8.298e-09	1.146
chr6:396321	rs12203592	IRF4	C>T	7832	193373	32.76	1.042e-08	1.078
chr22:19381507	rs5748177	HIRA	C>T	2211	51385	32.29	1.327e-08	1.136
chr23:106146349	rs5962774	MORC4	T>C	511	10515	28.96	7.393e-08	1.278
chr6:421281	rs62389423	-	G>A	6402	157634	28.56	9.074e-08	1.078
chr23:71628912	rs3012642	AL133500.1	A>G	981	21743	27.0	2.034e-07	1.188
chr14:49519533	rs55658248	-	G>T	3392	81524	26.5	2.641e-07	1.099
chr10:30240144	rs11007831	-	A>G	471	9742	25.52	4.37e-07	1.27
chr18:9536315	rs14336	RALBP1	A>C	580	12287	25.4	4.652e-07	1.24
chr18:33902503	rs487239	FHOD3	G>T	11751	295912	25.38	4.718e-07	1.06
chr1:85893389	rs17388437	DDAH1	T>C	2163	50938	25.2	5.162e-07	1.12
chr6:38636199	rs7739414	-	T>C	17215	438412	25.18	5.209e-07	1.056
chr10:49451051	rs1623017	FRMPD2	C>A	747	16253	25.08	5.499e-07	1.208
chr4:38197487	rs2380958	-	A>G	12584	317656	24.85	6.202e-07	1.058
chr2:30011868	rs4666273	ALK	G>C	740	16125	24.65	6.862e-07	1.207
chr10:21782842	rs5011832	-	T>C	13106	331770	23.98	9.729e-07	1.056
chr19:19258385	rs2238664	MEF2B	A>G	1798	42012	23.83	1.051e-06	1.128
chr5:83292653	rs6452558	EDIL3	G>A	1433	33032	23.65	1.158e-06	1.143
chr8:286684	rs73173360	-	C>T	2838	67977	23.44	1.292e-06	1.101
chr6:396321	rs12203592	IRF4	C>T	7729	191186	40.05	2.473e-10	1.087
chr6:421281	rs62389423	-	G>A	6304	155561	33.8	6.114e-09	1.086
chr4:38197487	rs2380958	-	A>G	11580	293694	26.83	2.216e-07	1.063
chr6:38636199	rs7739414	-	T>C	15921	408421	24.44	7.666e-07	1.057
chr10:21782842	rs5011832	-	T>C	12333	314407	23.82	1.057e-06	1.058
chr18:73985827	rs17349912	-	G>A	5687	141725	22.58	2.013e-06	1.073
chr10:21834536	rs7098100	MLLT10	G>A	11763	299605	22.46	2.144e-06	1.057
chr19:13927028	rs72995377	ZSWIM4	G>A	1328	39875	22.17	2.496e-06	0.8746
chr10:21957229	rs2183271	MLLT10	T>C	12297	312967	22.03	2.682e-06	1.056
chr3:49599902	rs80031977	BSN	T>C	1193	27540	21.66	3.255e-06	1.15
chr4:34348295	rs13132619	-	C>T	1063	24375	20.98	4.63e-06	1.157
chr3:48732846	rs61740999	IP6K2	G>A	1227	28437	20.81	5.084e-06	1.145
chr18:33902503	rs487239	FHOD3	G>T	10629	270254	20.79	5.134e-06	1.056
chr1:85893389	rs17388437	DDAH1	T>C	1989	47506	20.69	5.402e-06	1.113
chr1:98020955	rs17100624	DPYD	C>T	4734	117387	20.68	5.425e-06	1.075
chr1:77072458	rs2647389	ST6GALNAC3	T>C	5130	127674	20.63	5.584e-06	1.073
chr3:49740450	rs76100153	RNF123	C>T	1185	27419	20.56	5.77e-06	1.147
chr11:114925475	rs77722073	-	C>T	3536	86881	20.49	6.002e-06	1.086
chr7:103601362	rs7792642	RELN	C>T	11843	302354	20.44	6.166e-06	1.054
chr4:38199716	rs4833000	-	G>A	7135	179513	20.34	6.469e-06	1.063

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr2:221986879	rs73993864	-	G>T	1515	12059	25.2	5.167e-07	0.8694
chr6:38636199	rs7739414	-	T>C	15921	107660	24.53	7.302e-07	1.06
chr4:34348295	rs13132619	-	C>T	1063	6320	23.84	1.048e-06	1.179
chr4:38197487	rs2380958	-	A>G	11580	77591	23.55	1.215e-06	1.061
chr4:34390786	rs34906739	-	C>T	1207	7304	21.67	3.242e-06	1.159
chr13:30294932	rs117822967	-	C>T	469	2595	21.63	3.302e-06	1.264
chr8:2936213	rs34464519	CSMD1	A>G	2047	12827	21.16	4.232e-06	1.119
chr7:130951809	rs73153433	MKLN1	C>T	3654	23592	20.9	4.831e-06	1.09
chr18:73985827	rs17349912	-	G>A	5687	37395	20.86	4.929e-06	1.074
chr1:85893389	rs17388437	DDAH1	T>C	1989	12473	20.76	5.211e-06	1.12
chr19:13927028	rs72995377	ZSWIM4	G>A	1328	10535	20.52	5.902e-06	0.8741
chr16:78997549	rs71398117	WWOX	A>G	1088	6589	19.34	1.096e-05	1.157
chr8:286684	rs73173360	-	C>T	2549	16237	19.21	1.171e-05	1.102
chr11:114925475	rs77722073	-	C>T	3536	22907	19.16	1.203e-05	1.087
chr2:221987040	rs7604236	-	A>G	2016	15533	19.15	1.209e-05	0.8987
chr2:57730190	rs17048858	-	T>G	2457	15652	18.86	1.405e-05	1.103
chr8:72928677	rs34010392	-	T>C	1717	10730	18.55	1.654e-05	1.122
chr14:44461056	rs71412934	-	G>C	1869	14443	18.48	1.719e-05	0.897
chr4:74925367	rs76446141	-	C>T	883	5281	18.28	1.904e-05	1.17
chr9:8945265	rs58837186	PTPRD	C>T	6266	46045	18.15	2.042e-05	0.9383

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: C693	Choroid	2/20
ICD: D320	Cerebral meninges	1/20
ICD: D630	Anaemia in neoplastic disease	1/20
ICD: M5499	Dorsalgia, unspecified (Site unspecified)	2/20
ICD: R42	Dizziness and giddiness	1/20

ID	Name	Top Correlation
ICD-10: A415	Septicaemia due to other Gram-negative organisms	0/20
ICD-10: C719	Brain, unspecified	0/20
ICD-10: C793	Secondary malignant neoplasm of brain and cerebral meninges	0/20
ICD-10: D329	Meninges, unspecified	0/20
ICD-10: D370	Lip, oral cavity and pharynx	0/20
ICD-10: D432	Brain, unspecified	0/20
ICD-10: D758	Other specified diseases of blood and blood-forming organs	0/20
ICD-10: H050	Acute inflammation of orbit	0/20
ICD-10: H332	Serous retinal detachment	0/20
ICD-10: H531	Subjective visual disturbances	0/20
ICD-10: K862	Cyst of pancreas	0/20
ICD-10: M548	Other dorsalgia	0/20
ICD-10: M5490	Dorsalgia, unspecified (Multiple sites in spine)	0/20
ICD-10: M5494	Dorsalgia, unspecified (Thoracic region)	0/20
ICD-10: M5496	Dorsalgia, unspecified (Lumbar region)	0/20
ICD-10: R521	Chronic intractable pain	0/20
ICD-10: Y433	Other antineoplastic drugs	0/20

Neoplasm of the central nervous system

0100006

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ