Normal Case/Contol

GWAS of 0100242

Sibling Case/Control

No sibling GWAS available 0100242


Case Control
38348 421846

Phenotype Definition

A connective tissue neoplasm formed by proliferation of mesodermal cells. Bone and soft tissue sarcomas are the main types of sarcoma. Sarcoma is usually highly malignant. [HPO:sdoelken]

Phenotype Comment

A sarcoma (from the Greek sarx meaning flesh) is a general term describing a malignant neoplasm, or cancer, that arises from transformed connective tissue cells such as bone, cartilage and fat cells, which originate from embryonic mesoderm. This is in contrast to carcinomas, which are of epithelial origin (breast, colon, pancreas, and others). However, due to an evolving understanding of tissue origin, the term sarcoma is sometimes applied to tumors now known to arise from epithelial tissue. The term soft tissue sarcoma is used to describe tumors of soft tissue, which includes elements that are in connective tissue, but not derived from it (such as muscles and blood vessels).

Top SNP Information

Associated Diseases

ID Name Top Correlation
ICD: D24 Benign neoplasm of breast 6/20
ICD: D250 Submucous leiomyoma of uterus 9/20
ICD: D252 Subserosal leiomyoma of uterus 6/20
ICD: D259 Leiomyoma of uterus, unspecified 15/20
ICD: K083 Retained dental root 10/20
ICD: L989 Disorder of skin and subcutaneous tissue, unspecified 2/20
ICD: M5496 Dorsalgia, unspecified (Lumbar region) 1/20
ICD: M5499 Dorsalgia, unspecified (Site unspecified) 8/20