Case | Control |
---|---|
4885 | 455309 |
Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
---|---|---|---|---|---|---|---|---|
chr5:33951693 | rs16891982 | SLC45A2 | G>C | 488 | 66570 | 67.71 | 1.892e-16 | 0.6832 |
chr5:33958959 | rs28777 | SLC45A2 | A>C | 424 | 56568 | 51.09 | 8.805e-13 | 0.7018 |
chr5:33951116 | rs35397 | SLC45A2 | T>G | 753 | 89355 | 40.15 | 2.352e-10 | 0.7862 |
chr15:78783277 | rs11858836 | IREB2 | G>A | 3424 | 298971 | 38.34 | 5.946e-10 | 1.14 |
chr5:33955326 | rs35390 | SLC45A2 | A>C | 306 | 40841 | 36.26 | 1.722e-09 | 0.7053 |
chr12:12477531 | rs4763815 | - | C>T | 270 | 36780 | 35.77 | 2.217e-09 | 0.6919 |
chr15:78806023 | rs8034191 | HYKK | T>C | 3596 | 315821 | 35.44 | 2.631e-09 | 1.132 |
chr15:78857939 | rs55853698 | CHRNA5 | T>G | 3574 | 313836 | 35.42 | 2.66e-09 | 1.132 |
chr6:136480972 | rs9483910 | PDE7B | C>T | 135 | 21235 | 35.03 | 3.253e-09 | 0.6011 |
chr5:33955673 | rs35391 | SLC45A2 | C>T | 307 | 40673 | 34.75 | 3.748e-09 | 0.7108 |
chr17:5845873 | rs16955272 | AC007846.2 | G>A | 123 | 19739 | 34.61 | 4.039e-09 | 0.5891 |
chr15:78868636 | rs72740964 | CHRNA5 | G>A | 3487 | 305788 | 34.46 | 4.357e-09 | 1.132 |
chr15:78882925 | rs16969968 | CHRNA5 | G>A | 3528 | 309861 | 34.35 | 4.607e-09 | 1.131 |
chr15:78802869 | rs9788721 | HYKK | T>C | 3710 | 326899 | 33.56 | 6.909e-09 | 1.128 |
chr12:50324973 | rs611484 | - | G>A | 342 | 44197 | 33.1 | 8.741e-09 | 0.7287 |
chr1:862124 | rs13303101 | SAMD11 | G>A | 262 | 35242 | 32.34 | 1.294e-08 | 0.7009 |
chr15:78878541 | rs951266 | CHRNA5 | G>A | 3520 | 310056 | 32.28 | 1.332e-08 | 1.127 |
chr15:28335820 | rs4778138 | OCA2 | A>G | 1205 | 133570 | 31.98 | 1.556e-08 | 0.8402 |
chr15:78896129 | rs1317286 | CHRNA3 | A>G | 3586 | 316501 | 31.28 | 2.232e-08 | 1.124 |
chr13:72441665 | rs3759505 | - | C>T | 101 | 16614 | 31.17 | 2.363e-08 | 0.5752 |
chr15:78802869 | rs9788721 | HYKK | T>C | 3587 | 308990 | 32.66 | 1.1e-08 | 1.128 |
chr15:78783277 | rs11858836 | IREB2 | G>A | 3360 | 290006 | 29.31 | 6.175e-08 | 1.123 |
chr15:78806023 | rs8034191 | HYKK | T>C | 3512 | 304017 | 28.47 | 9.508e-08 | 1.12 |
chr15:78857939 | rs55853698 | CHRNA5 | T>G | 3506 | 303937 | 27.48 | 1.589e-07 | 1.118 |
chr15:78826180 | rs931794 | HYKK | A>G | 3520 | 305169 | 27.31 | 1.734e-07 | 1.117 |
chr15:78896129 | rs1317286 | CHRNA3 | A>G | 3491 | 302792 | 26.82 | 2.229e-07 | 1.116 |
chr15:78814046 | rs10519203 | HYKK | A>G | 3517 | 305431 | 26.66 | 2.429e-07 | 1.116 |
chr15:78882925 | rs16969968 | CHRNA5 | G>A | 3464 | 300480 | 26.37 | 2.813e-07 | 1.115 |
chr15:78868636 | rs72740964 | CHRNA5 | G>A | 3423 | 296443 | 26.32 | 2.897e-07 | 1.116 |
chr15:78878541 | rs951266 | CHRNA5 | G>A | 3451 | 299621 | 25.87 | 3.644e-07 | 1.114 |
chr15:78867482 | rs17486278 | CHRNA5 | A>C | 3465 | 300756 | 25.85 | 3.691e-07 | 1.114 |
chr15:78857986 | rs55781567 | CHRNA5 | C>G | 3500 | 303875 | 25.82 | 3.741e-07 | 1.114 |
chr7:91187760 | rs12536116 | - | A>C | 764 | 84859 | 25.72 | 3.942e-07 | 0.8255 |
chr15:78898723 | rs12914385 | CHRNA3 | C>T | 3967 | 346886 | 25.52 | 4.375e-07 | 1.11 |
chr15:78894339 | rs1051730 | CHRNA3 | G>A | 3451 | 300129 | 25.17 | 5.254e-07 | 1.113 |
chr2:45983392 | rs1468041 | PRKCE | G>T | 153 | 9521 | 24.99 | 5.763e-07 | 1.503 |
chr15:78873993 | rs7180002 | CHRNA5 | A>T | 3445 | 299540 | 24.5 | 7.445e-07 | 1.111 |
chr7:89897703 | rs17863057 | CFAP69 | A>C | 391 | 28532 | 23.97 | 9.778e-07 | 1.289 |
chr15:78911672 | rs4243084 | CHRNA3 | G>C | 3505 | 305368 | 23.41 | 1.31e-06 | 1.108 |
chr17:29243402 | rs117870634 | ADAP2 | A>G | 169 | 22705 | 23.26 | 1.417e-06 | 0.6883 |
Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
---|---|---|---|---|---|---|---|---|
chr5:33951693 | rs16891982 | SLC45A2 | G>C | 488 | 2368 | 42.33 | 7.714e-11 | 0.7184 |
chr5:33958959 | rs28777 | SLC45A2 | A>C | 424 | 1990 | 28.77 | 8.171e-08 | 0.7464 |
chr12:12477531 | rs4763815 | - | C>T | 270 | 1342 | 26.29 | 2.932e-07 | 0.7079 |
chr5:127265136 | rs9327457 | CCDC192 | C>T | 174 | 934 | 25.96 | 3.479e-07 | 0.6559 |
chr12:50324973 | rs611484 | - | G>A | 342 | 1617 | 24.17 | 8.825e-07 | 0.7431 |
chr3:16991193 | rs77425173 | PLCL2 | G>A | 498 | 1381 | 23.7 | 1.123e-06 | 1.297 |
chr8:95175763 | rs28521190 | CDH17 | G>T | 179 | 937 | 23.44 | 1.29e-06 | 0.6729 |
chr9:74195202 | rs117762156 | - | G>A | 352 | 930 | 23.39 | 1.325e-06 | 1.359 |
chr8:14533608 | rs73202815 | SGCZ | A>G | 831 | 2452 | 23.17 | 1.483e-06 | 1.223 |
chr13:65485756 | rs1588684 | - | G>A | 2720 | 8840 | 22.73 | 1.864e-06 | 1.13 |
chr17:5845873 | rs16955272 | AC007846.2 | G>A | 123 | 691 | 22.63 | 1.963e-06 | 0.6284 |
chr12:33458768 | rs13377955 | - | C>A | 500 | 2230 | 22.53 | 2.065e-06 | 0.7861 |
chr1:1221138 | rs11260578 | SCNN1D | G>A | 209 | 1059 | 22.2 | 2.461e-06 | 0.6985 |
chr10:108242222 | rs10884325 | - | A>G | 731 | 3122 | 22.16 | 2.513e-06 | 0.8181 |
chr2:45983392 | rs1468041 | PRKCE | G>T | 155 | 352 | 22.06 | 2.648e-06 | 1.572 |
chr2:77627190 | rs13407647 | LRRTM4 | C>T | 158 | 837 | 21.94 | 2.814e-06 | 0.6656 |
chr1:211250618 | rs113408573 | KCNH1 | C>T | 151 | 342 | 21.77 | 3.067e-06 | 1.576 |
chr17:29243402 | rs117870634 | ADAP2 | A>G | 169 | 879 | 21.36 | 3.816e-06 | 0.6775 |
chr15:28327835 | rs4778137 | OCA2 | C>G | 2863 | 11041 | 21.32 | 3.885e-06 | 0.8915 |
chr7:155086997 | rs34031777 | - | A>G | 4470 | 16816 | 20.85 | 4.957e-06 | 0.9017 |
chr3:17150697 | rs55641789 | - | A>G | 1793 | 5551 | 23.29 | 1.394e-06 | 1.156 |
chr17:29243402 | rs117870634 | ADAP2 | A>G | 169 | 863 | 21.4 | 3.722e-06 | 0.6768 |
chr3:16991193 | rs77425173 | PLCL2 | G>A | 491 | 1354 | 20.87 | 4.908e-06 | 1.279 |
chr18:41867582 | rs17769286 | - | G>C | 1141 | 4576 | 20.64 | 5.55e-06 | 0.852 |
chr1:211250618 | rs113408573 | KCNH1 | C>T | 148 | 333 | 20.11 | 7.316e-06 | 1.557 |
chr2:45983392 | rs1468041 | PRKCE | G>T | 153 | 348 | 19.79 | 8.643e-06 | 1.539 |
chr5:127265136 | rs9327457 | CCDC192 | C>T | 122 | 653 | 19.55 | 9.787e-06 | 0.6468 |
chr10:79362803 | rs57526643 | KCNMA1 | C>T | 945 | 3827 | 19.4 | 1.059e-05 | 0.8449 |
chr1:27050453 | rs114693082 | ARID1A | G>A | 247 | 622 | 19.38 | 1.073e-05 | 1.396 |
chr7:91187760 | rs12536116 | - | A>C | 764 | 3146 | 18.76 | 1.486e-05 | 0.8336 |
chr9:140758025 | rs72767001 | EHMT1 | A>G | 1965 | 6189 | 18.64 | 1.582e-05 | 1.133 |
chr16:52807290 | rs61131526 | - | G>A | 59 | 371 | 18.32 | 1.869e-05 | 0.5525 |
chr17:28793630 | rs76570178 | CPD | A>G | 245 | 1146 | 18.11 | 2.086e-05 | 0.739 |
chr18:67346440 | rs12604978 | DOK6 | A>C | 4461 | 16387 | 18.11 | 2.081e-05 | 0.9065 |
chr5:150432153 | rs2112635 | TNIP1 | T>C | 3189 | 10368 | 18.01 | 2.197e-05 | 1.111 |
chr7:11294325 | rs77616119 | - | G>A | 97 | 202 | 17.86 | 2.38e-05 | 1.68 |
chr13:65485756 | rs1588684 | - | G>A | 2685 | 8652 | 17.65 | 2.653e-05 | 1.115 |
chr11:121491307 | rs10892760 | SORL1 | C>A | 4707 | 15594 | 17.59 | 2.747e-05 | 1.101 |
chr7:89897703 | rs17863057 | CFAP69 | A>C | 391 | 1069 | 17.57 | 2.769e-05 | 1.287 |
chr9:4080699 | rs3925024 | GLIS3 | T>C | 2281 | 7281 | 17.56 | 2.791e-05 | 1.121 |