Statistics
| Case | Control |
|---|---|
| 3548 | 456646 |
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr15:78802869 | rs9788721 | HYKK | T>C | 2743 | 327866 | 33.16 | 8.492e-09 | 1.149 |
| chr15:78806023 | rs8034191 | HYKK | T>C | 2654 | 316763 | 33.07 | 8.903e-09 | 1.15 |
| chr15:78783277 | rs11858836 | IREB2 | G>A | 2521 | 299874 | 32.82 | 1.012e-08 | 1.152 |
| chr15:78857939 | rs55853698 | CHRNA5 | T>G | 2632 | 314778 | 31.32 | 2.193e-08 | 1.146 |
| chr8:114195035 | rs62519807 | CSMD3 | T>C | 523 | 54255 | 29.73 | 4.963e-08 | 1.281 |
| chr15:78826180 | rs931794 | HYKK | A>G | 2677 | 321351 | 29.33 | 6.115e-08 | 1.141 |
| chr5:33951693 | rs16891982 | SLC45A2 | G>C | 392 | 66666 | 29.05 | 7.048e-08 | 0.756 |
| chr15:78814046 | rs10519203 | HYKK | A>G | 2676 | 321733 | 28.99 | 7.293e-08 | 1.14 |
| chr15:78898723 | rs12914385 | CHRNA3 | C>T | 2993 | 361965 | 28.84 | 7.85e-08 | 1.136 |
| chr15:78868636 | rs72740964 | CHRNA5 | G>A | 2560 | 306715 | 28.31 | 1.036e-07 | 1.14 |
| chr15:78882925 | rs16969968 | CHRNA5 | G>A | 2590 | 310799 | 28.19 | 1.1e-07 | 1.139 |
| chr15:78857986 | rs55781567 | CHRNA5 | C>G | 2650 | 318665 | 27.88 | 1.291e-07 | 1.137 |
| chr15:78878541 | rs951266 | CHRNA5 | G>A | 2587 | 310989 | 27.05 | 1.978e-07 | 1.136 |
| chr15:78774271 | rs8042238 | IREB2 | T>C | 2704 | 382455 | 26.58 | 2.535e-07 | 0.8826 |
| chr6:33373953 | rs111461772 | KIFC1 | C>A | 449 | 46393 | 26.3 | 2.93e-07 | 1.284 |
| chr15:78754000 | rs1964678 | IREB2 | G>A | 2692 | 380478 | 26.12 | 3.202e-07 | 0.8835 |
| chr15:78894339 | rs1051730 | CHRNA3 | G>A | 2586 | 311556 | 25.77 | 3.847e-07 | 1.132 |
| chr15:78873993 | rs7180002 | CHRNA5 | A>T | 2581 | 310907 | 25.77 | 3.846e-07 | 1.132 |
| chr10:13207277 | rs10906317 | MCM10 | G>C | 2844 | 345115 | 25.29 | 4.924e-07 | 1.128 |
| chr15:78789488 | rs13180 | IREB2 | T>C | 2715 | 382533 | 25.0 | 5.747e-07 | 0.8861 |
| chr15:78802869 | rs9788721 | HYKK | T>C | 2641 | 309936 | 33.49 | 7.166e-09 | 1.153 |
| chr15:78806023 | rs8034191 | HYKK | T>C | 2586 | 304943 | 29.65 | 5.176e-08 | 1.144 |
| chr15:78783277 | rs11858836 | IREB2 | G>A | 2470 | 290896 | 28.39 | 9.911e-08 | 1.143 |
| chr15:78857939 | rs55853698 | CHRNA5 | T>G | 2579 | 304864 | 28.01 | 1.207e-07 | 1.14 |
| chr15:78826180 | rs931794 | HYKK | A>G | 2588 | 306101 | 27.6 | 1.494e-07 | 1.139 |
| chr15:78814046 | rs10519203 | HYKK | A>G | 2587 | 306361 | 27.5 | 1.568e-07 | 1.139 |
| chr8:114195035 | rs62519807 | CSMD3 | T>C | 510 | 52556 | 26.68 | 2.405e-07 | 1.269 |
| chr15:78898723 | rs12914385 | CHRNA3 | C>T | 2917 | 347936 | 26.67 | 2.415e-07 | 1.133 |
| chr15:78857986 | rs55781567 | CHRNA5 | C>G | 2573 | 304802 | 26.47 | 2.677e-07 | 1.136 |
| chr15:78882925 | rs16969968 | CHRNA5 | G>A | 2541 | 301403 | 25.12 | 5.376e-07 | 1.133 |
| chr15:78868636 | rs72740964 | CHRNA5 | G>A | 2511 | 297355 | 25.01 | 5.709e-07 | 1.133 |
| chr15:78878541 | rs951266 | CHRNA5 | G>A | 2532 | 300540 | 24.56 | 7.196e-07 | 1.131 |
| chr15:78867482 | rs17486278 | CHRNA5 | A>C | 2541 | 301680 | 24.46 | 7.601e-07 | 1.131 |
| chr15:78894339 | rs1051730 | CHRNA3 | G>A | 2533 | 301047 | 23.93 | 1e-06 | 1.129 |
| chr15:78896129 | rs1317286 | CHRNA3 | A>G | 2554 | 303729 | 23.7 | 1.125e-06 | 1.128 |
| chr15:78911672 | rs4243084 | CHRNA3 | G>C | 2573 | 306300 | 23.26 | 1.417e-06 | 1.127 |
| chr15:78873993 | rs7180002 | CHRNA5 | A>T | 2526 | 300459 | 23.17 | 1.482e-06 | 1.127 |
| chr6:33373953 | rs111461772 | KIFC1 | C>A | 445 | 45884 | 23.02 | 1.601e-06 | 1.266 |
| chr16:11422899 | rs2002751 | RMI2 | C>G | 223 | 20914 | 22.85 | 1.748e-06 | 1.385 |
| chr10:13207277 | rs10906317 | MCM10 | G>C | 2748 | 329051 | 22.8 | 1.793e-06 | 1.124 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr8:114195035 | rs62519807 | CSMD3 | T>C | 510 | 5774 | 26.36 | 2.835e-07 | 1.278 |
| chr15:78802869 | rs9788721 | HYKK | T>C | 2641 | 34580 | 26.06 | 3.307e-07 | 1.139 |
| chr15:78806023 | rs8034191 | HYKK | T>C | 2586 | 34019 | 22.9 | 1.71e-06 | 1.13 |
| chr16:11422899 | rs2002751 | RMI2 | C>G | 223 | 2291 | 22.4 | 2.209e-06 | 1.399 |
| chr8:115317442 | rs1588904 | - | T>C | 3308 | 44049 | 22.26 | 2.385e-06 | 1.127 |
| chr15:78857939 | rs55853698 | CHRNA5 | T>G | 2579 | 33991 | 21.79 | 3.046e-06 | 1.127 |
| chr10:13207277 | rs10906317 | MCM10 | G>C | 2748 | 36394 | 21.6 | 3.364e-06 | 1.125 |
| chr15:78826180 | rs931794 | HYKK | A>G | 2588 | 34144 | 21.06 | 4.448e-06 | 1.124 |
| chr15:78857986 | rs55781567 | CHRNA5 | C>G | 2573 | 33950 | 20.96 | 4.678e-06 | 1.124 |
| chr15:78814046 | rs10519203 | HYKK | A>G | 2587 | 34177 | 20.94 | 4.747e-06 | 1.124 |
| chr15:78898723 | rs12914385 | CHRNA3 | C>T | 2917 | 38779 | 20.49 | 5.988e-06 | 1.12 |
| chr8:115399781 | rs186013 | - | T>C | 3363 | 45004 | 20.44 | 6.162e-06 | 1.12 |
| chr17:54150021 | rs6505033 | ANKFN1 | G>C | 1664 | 21367 | 20.4 | 6.289e-06 | 1.14 |
| chr10:19948256 | rs11815338 | MALRD1 | G>A | 66 | 1634 | 20.26 | 6.763e-06 | 0.5709 |
| chr12:68624149 | rs11570905 | - | T>C | 198 | 2024 | 19.99 | 7.802e-06 | 1.4 |
| chr15:78783277 | rs11858836 | IREB2 | G>A | 2470 | 32574 | 19.96 | 7.922e-06 | 1.122 |
| chr6:169369886 | rs9455812 | - | G>A | 680 | 8173 | 19.64 | 9.343e-06 | 1.204 |
| chr6:77345229 | rs2504435 | - | G>A | 155 | 1528 | 19.62 | 9.465e-06 | 1.455 |
| chr7:97406264 | rs6465617 | - | T>C | 938 | 15288 | 19.49 | 1.01e-05 | 0.8527 |
| chr8:115354322 | rs2357362 | - | T>C | 2835 | 37729 | 19.43 | 1.043e-05 | 1.117 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: C349 | Bronchus or lung, unspecified | 14/20 |
| ICD: J984 | Other disorders of lung | 1/20 |
| ID | Name | Top Correlation |
|---|---|---|
| ICD-10: D381 | Trachea, bronchus and lung | 0/20 |