Neoplasm of the respiratory system

0100606

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

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Interactive Plot

Statistics

Case	Control
10304	449890

Phenotype Definition

A tumor (abnormal growth of tissue) of the respiratory system. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr5:33951693	rs16891982	SLC45A2	G>C	1083	65975	113.5	1.696e-26	0.7165
chr5:33958959	rs28777	SLC45A2	A>C	937	56055	86.19	1.635e-20	0.7323
chr5:147863034	rs9325101	HTR4	A>G	213	16527	67.85	1.764e-16	0.5693
chr5:33951116	rs35397	SLC45A2	T>G	1643	88465	65.47	5.899e-16	0.8111
chr6:136480972	rs9483910	PDE7B	C>T	305	21065	60.18	8.656e-15	0.6396
chr5:33955326	rs35390	SLC45A2	A>C	683	40464	57.68	3.078e-14	0.7432
chr15:48426484	rs1426654	SLC24A5	A>G	424	27102	56.78	4.869e-14	0.6904
chr5:33955673	rs35391	SLC45A2	C>T	685	40295	54.97	1.225e-13	0.7487
chr5:9203914	rs1805972	SEMA5A	T>C	603	36071	54.12	1.887e-13	0.7369
chr5:148191544	rs2895794	-	G>C	273	18850	53.6	2.453e-13	0.6405
chr23:102201216	rs725570	-	A>G	252	18718	47.56	5.337e-12	0.6456
chr1:236085940	rs12038310	-	C>T	213	15063	46.53	9.035e-12	0.6258
chr16:28995057	rs11859822	SPNS1	T>C	478	28958	46.31	1.008e-11	0.729
chr5:33999671	rs34678	AMACR	A>G	376	23688	46.25	1.04e-11	0.7013
chr15:29223282	rs8026324	APBA2	T>A	717	40959	46.01	1.175e-11	0.7717
chr5:83128858	rs7709612	-	A>G	141	10953	44.83	2.153e-11	0.5701
chr9:10063634	rs445608	PTPRD	G>A	343	21778	43.78	3.672e-11	0.6969
chr14:33956209	rs1012023	NPAS3	C>A	553	32507	43.77	3.69e-11	0.7509
chr9:137925543	rs7027926	-	G>A	245	16575	43.67	3.881e-11	0.654
chr15:78783277	rs11858836	IREB2	G>A	7076	295319	43.04	5.363e-11	1.101
chr6:32155581	rs204993	PBX2	A>G	6940	285803	33.98	5.573e-09	1.091
chr6:31127562	rs1150765	TCF19	C>T	5687	232492	33.48	7.21e-09	1.096
chr6:31138107	rs1062630	POU5F1	G>A	5535	226561	32.92	9.591e-09	1.096
chr6:31147194	rs3130457	POU5F1	T>C	5599	228841	31.86	1.653e-08	1.094
chr6:32205942	rs6901158	-	C>T	3637	145737	31.44	2.057e-08	1.109
chr15:78783277	rs11858836	IREB2	G>A	6931	286435	30.98	2.606e-08	1.087
chr6:31125978	rs3130455	CCHCR1	A>T	5331	217495	30.59	3.192e-08	1.093
chr6:32148031	rs1062070	RNF5	A>G	4367	176816	30.41	3.498e-08	1.1
chr6:31143652	rs887465	POU5F1	C>G	5570	228115	30.36	3.584e-08	1.091
chr6:32147696	rs3130349	RNF5	G>A	4407	178500	30.31	3.686e-08	1.099
chr6:32345689	rs2894254	-	T>G	2914	115660	29.46	5.696e-08	1.116
chr15:78802869	rs9788721	HYKK	T>C	7364	305213	29.15	6.702e-08	1.083
chr6:32151934	rs3131300	AGER	A>G	4374	177589	28.93	7.51e-08	1.097
chr6:32290208	rs9268235	TSBP1	C>T	2955	117538	28.82	7.951e-08	1.114
chr6:32261252	rs7775397	TSBP1	T>G	2922	116200	28.57	9.032e-08	1.114
chr6:32310863	rs2849018	TSBP1	T>C	2923	116267	28.3	1.041e-07	1.113
chr6:31122482	rs130076	CCHCR1	G>A	5276	216077	28.25	1.067e-07	1.09
chr6:32325562	rs2395149	TSBP1	G>A	2918	116134	28.07	1.172e-07	1.113
chr6:31112737	rs130079	CCHCR1	C>A	5632	231420	27.94	1.253e-07	1.087
chr15:78806023	rs8034191	HYKK	T>C	7238	300291	27.83	1.328e-07	1.081

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr6:31127562	rs1150765	TCF19	C>T	5687	128445	32.14	1.435e-08	1.095
chr6:31138107	rs1062630	POU5F1	G>A	5535	125069	31.61	1.887e-08	1.095
chr6:31147194	rs3130457	POU5F1	T>C	5599	126517	29.89	4.582e-08	1.091
chr6:32155581	rs204993	PBX2	A>G	6940	158346	29.44	5.774e-08	1.085
chr6:32205942	rs6901158	-	C>T	3637	80675	28.85	7.828e-08	1.106
chr6:31125978	rs3130455	CCHCR1	A>T	5331	120225	28.72	8.372e-08	1.091
chr6:31143652	rs887465	POU5F1	C>G	5570	126108	28.48	9.458e-08	1.089
chr15:78783277	rs11858836	IREB2	G>A	6931	158419	28.36	1.01e-07	1.084
chr6:32147696	rs3130349	RNF5	G>A	4407	98803	27.64	1.46e-07	1.096
chr6:32148031	rs1062070	RNF5	A>G	4367	97913	27.49	1.582e-07	1.096
chr15:78802869	rs9788721	HYKK	T>C	7364	168687	27.34	1.709e-07	1.081
chr6:31122482	rs130076	CCHCR1	G>A	5276	119467	26.5	2.634e-07	1.088
chr6:31112737	rs130079	CCHCR1	C>A	5632	127901	26.4	2.774e-07	1.086
chr6:32151934	rs3131300	AGER	A>G	4374	98300	26.33	2.876e-07	1.093
chr6:31190303	rs3130517	-	T>C	6500	148230	26.28	2.96e-07	1.082
chr15:78806023	rs8034191	HYKK	T>C	7238	165985	25.96	3.494e-07	1.079
chr6:32345689	rs2894254	-	T>G	2914	64167	25.91	3.58e-07	1.11
chr6:31177094	rs3130953	-	G>A	6508	148598	25.7	3.987e-07	1.081
chr15:78857986	rs55781567	CHRNA5	C>G	7226	165818	25.68	4.036e-07	1.078
chr6:32290208	rs9268235	TSBP1	C>T	2955	65200	25.47	4.482e-07	1.108

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: C349	Bronchus or lung, unspecified	2/20
ICD: C450	Mesothelioma of pleura	1/20
ICD: C780	Secondary malignant neoplasm of lung	7/20
ICD: J920	Pleural plaque with presence of asbestos	2/20
ICD: J929	Pleural plaque without asbestos	2/20

ID	Name	Top Correlation
ICD-10: C329	Larynx, unspecified	0/20
ICD-10: C459	Mesothelioma, unspecified	0/20
ICD-10: C782	Secondary malignant neoplasm of pleura	0/20
ICD-10: C830	Small cell (diffuse)	0/20
ICD-10: C833	Large cell (diffuse)	0/20
ICD-10: C851	B-cell lymphoma, unspecified	0/20
ICD-10: D140	Middle ear, nasal cavity and accessory sinuses	0/20
ICD-10: D370	Lip, oral cavity and pharynx	0/20
ICD-10: D381	Trachea, bronchus and lung	0/20
ICD-10: J370	Chronic laryngitis	0/20
ICD-10: J387	Other diseases of larynx	0/20
ICD-10: J948	Other specified pleural conditions	0/20
ICD-10: J984	Other disorders of lung	0/20

Neoplasm of the respiratory system

0100606

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ