Neoplasm of the respiratory system

0100606

Female ^ⓘ

Male ^ⓘ

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Statistics

Female Case	Female Control	% Female
4334	245523	42%

Male Case	Male Control	% Male
5970	204367	58%

Phenotype Definition

A tumor (abnormal growth of tissue) of the respiratory system. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr5:33951693	rs16891982	SLC45A2	G>C	494	35713	27.34	1.704e-07	0.7842
chr23:102201216	rs725570	-	A>G	157	13402	25.13	5.364e-07	0.6682
chr2:37833444	rs13430233	-	G>A	384	17284	23.59	1.189e-06	1.291
chr5:148191544	rs2895794	-	G>C	116	10413	23.37	1.339e-06	0.6373
chr6:32205942	rs6901158	-	C>T	1607	82731	22.91	1.694e-06	1.142
chr16:18160867	rs76649197	-	T>G	453	20902	22.59	2.006e-06	1.26
chr8:56344186	rs13439780	XKR4	C>T	273	20839	22.55	2.049e-06	0.7462
chr1:5773754	rs12074462	-	A>G	92	8616	22.42	2.196e-06	0.6103
chr6:31138107	rs1062630	POU5F1	G>A	2434	129177	22.42	2.188e-06	1.12
chr6:31125978	rs3130455	CCHCR1	A>T	2319	122395	21.71	3.175e-06	1.12
chr3:77042793	rs73106483	ROBO2	C>G	266	11516	21.7	3.19e-06	1.339
chr8:17567050	rs17633964	MTUS1	T>C	232	18033	21.56	3.432e-06	0.7337
chr5:132432075	rs72801465	HSPA4	G>A	618	29650	21.55	3.448e-06	1.216
chr6:31143511	rs887466	POU5F1	G>A	3088	189907	21.53	3.479e-06	0.9014
chr4:89287096	rs4693957	-	G>A	865	57786	21.34	3.854e-06	0.8469
chr16:18109185	rs238838	-	T>C	445	20649	21.16	4.231e-06	1.253
chr6:31269173	rs9366778	HLA-B	G>A	3146	193526	21.11	4.328e-06	0.9027
chr12:29872567	rs12582196	TMTC1	C>T	180	14516	21.04	4.505e-06	0.7077
chr18:58950357	rs11665042	-	A>G	2152	113439	21.04	4.494e-06	1.121
chr6:32147696	rs3130349	RNF5	G>A	1934	101314	20.92	4.793e-06	1.126
chr18:58950357	rs11665042	-	A>G	2100	108256	23.65	1.155e-06	1.131
chr2:98997682	rs3754900	CNGA3	T>C	1026	50659	21.18	4.187e-06	1.167
chr2:37833444	rs13430233	-	G>A	379	17036	20.7	5.366e-06	1.273
chr6:32205942	rs6901158	-	C>T	1558	79373	20.39	6.309e-06	1.136
chr11:91994044	rs16917259	-	T>C	1274	80960	20.11	7.293e-06	0.8719
chr1:10463961	rs115789191	PGD	T>C	150	12185	19.9	8.144e-06	0.6923
chr1:84129373	rs78831648	-	G>T	115	4303	19.74	8.872e-06	1.521
chr3:77042793	rs73106483	ROBO2	C>G	261	11246	19.71	8.992e-06	1.325
chr18:58987231	rs12967139	-	A>G	2976	157534	19.56	9.762e-06	1.106
chr6:31143511	rs887466	POU5F1	G>A	2953	178333	19.06	1.266e-05	0.905
chr22:17984525	rs78771124	CECR2	C>A	113	9589	18.82	1.437e-05	0.6634
chr11:91979120	rs12577025	-	G>A	1808	111873	18.42	1.77e-05	0.8919
chr6:31062667	rs2517448	-	C>T	3122	188070	18.39	1.799e-05	0.9077
chr16:18160867	rs76649197	-	T>G	443	20521	18.34	1.852e-05	1.235
chr5:132432075	rs72801465	HSPA4	G>A	611	29247	18.33	1.859e-05	1.199
chr18:6505881	rs8091102	-	G>A	504	23665	18.33	1.857e-05	1.219
chr4:12294682	rs28502675	-	G>T	2050	106893	18.22	1.971e-05	1.115
chr6:32151934	rs3131300	AGER	A>G	1869	96911	18.19	2.002e-05	1.119
chr1:5773754	rs12074462	-	A>G	61	5913	18.06	2.139e-05	0.5814
chr6:32147696	rs3130349	RNF5	G>A	1878	97400	18.05	2.146e-05	1.118

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr5:33951693	rs16891982	SLC45A2	G>C	589	30262	92.3	7.441e-22	0.6657
chr5:33958959	rs28777	SLC45A2	A>C	503	25649	74.92	4.907e-18	0.6734
chr5:33951116	rs35397	SLC45A2	T>G	916	40513	55.47	9.474e-14	0.7726
chr6:136480972	rs9483910	PDE7B	C>T	140	9089	55.46	9.539e-14	0.5339
chr5:147863034	rs9325101	HTR4	A>G	100	7056	51.3	7.941e-13	0.492
chr5:33955326	rs35390	SLC45A2	A>C	378	18695	46.58	8.774e-12	0.6989
chr8:34790660	rs6982495	-	C>T	148	8996	46.37	9.803e-12	0.571
chr5:33955673	rs35391	SLC45A2	C>T	378	18610	45.29	1.702e-11	0.7024
chr10:31512098	rs2484992	-	C>T	170	9898	45.09	1.878e-11	0.5961
chr10:31515132	rs2484990	-	C>T	172	9970	44.9	2.077e-11	0.5985
chr16:17200685	rs8046024	XYLT1	C>T	142	8652	44.78	2.203e-11	0.57
chr16:17200759	rs8044934	XYLT1	G>A	140	8544	44.54	2.495e-11	0.5687
chr10:31495974	rs1250307	-	A>G	170	9836	43.95	3.37e-11	0.6
chr5:100978551	rs6895527	-	A>G	180	10271	43.45	4.357e-11	0.61
chr11:61144707	rs1377458	-	T>C	147	8777	42.97	5.557e-11	0.5817
chr8:145639681	rs1871534	SLC39A4	G>C	121	7604	42.74	6.262e-11	0.5525
chr6:38681447	rs7774234	-	T>C	84	5871	41.77	1.029e-10	0.4974
chr21:32375769	rs2833191	-	A>G	1425	58562	41.59	1.125e-10	0.8323
chr8:16105860	rs10888117	MSR1	C>A	214	11576	41.4	1.243e-10	0.6414
chr5:33999671	rs34678	AMACR	A>G	188	10443	40.98	1.539e-10	0.6248
chr6:53181705	rs13208390	ELOVL5	T>G	229	5723	22.21	2.446e-06	1.376
chr2:25655371	rs78433554	DTNB	C>A	135	6899	21.95	2.804e-06	0.6659
chr16:455646	rs873477	NME4	A>G	5046	164304	21.04	4.501e-06	1.09
chr6:32155581	rs204993	PBX2	A>G	4027	129829	20.73	5.28e-06	1.094
chr6:30121460	rs2022065	TRIM10	C>T	3314	121342	20.66	5.483e-06	0.9101
chr6:28325201	rs6921919	ZKSCAN3	C>G	3087	98450	19.91	8.119e-06	1.099
chr14:32194024	rs4981892	NUBPL	G>A	843	24822	19.87	8.278e-06	1.176
chr5:141044179	rs62380786	ARAP3	C>T	1143	34457	19.59	9.605e-06	1.15
chr1:32036927	rs9425884	-	T>C	5674	185755	19.58	9.623e-06	1.086
chr6:41451841	rs11965261	-	A>G	1603	49493	19.27	1.135e-05	1.127
chr6:5618987	rs11962015	FARS2	G>A	1995	74719	19.14	1.214e-05	0.897
chr1:168370260	rs2268544	-	A>G	316	13811	19.13	1.224e-05	0.7776
chr23:70459753	rs1803001	ZMYM3	A>G	452	12650	18.87	1.399e-05	1.241
chr6:28325308	rs6922111	ZKSCAN3	C>T	3079	98469	18.75	1.492e-05	1.096
chr13:65287791	rs11843599	-	C>T	1880	70573	18.72	1.515e-05	0.8957
chr6:32109979	rs204999	-	A>G	3882	125476	18.66	1.564e-05	1.089
chr19:17902177	rs11672054	-	G>A	1337	51137	18.61	1.603e-05	0.8809
chr6:32158319	rs176095	-	A>G	3241	103933	18.52	1.683e-05	1.094
chr7:96027768	rs2107285	-	T>C	3723	120056	18.5	1.702e-05	1.09
chr19:52016530	rs12463300	-	A>G	676	27155	18.45	1.745e-05	0.842

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: C349	Bronchus or lung, unspecified	2/20
ICD: C450	Mesothelioma of pleura	1/20
ICD: C780	Secondary malignant neoplasm of lung	7/20
ICD: J920	Pleural plaque with presence of asbestos	2/20
ICD: J929	Pleural plaque without asbestos	2/20

ID	Name	Top Correlation
ICD-10: C329	Larynx, unspecified	0/20
ICD-10: C459	Mesothelioma, unspecified	0/20
ICD-10: C782	Secondary malignant neoplasm of pleura	0/20
ICD-10: C830	Small cell (diffuse)	0/20
ICD-10: C833	Large cell (diffuse)	0/20
ICD-10: C851	B-cell lymphoma, unspecified	0/20
ICD-10: D140	Middle ear, nasal cavity and accessory sinuses	0/20
ICD-10: D370	Lip, oral cavity and pharynx	0/20
ICD-10: D381	Trachea, bronchus and lung	0/20
ICD-10: J370	Chronic laryngitis	0/20
ICD-10: J387	Other diseases of larynx	0/20
ICD-10: J948	Other specified pleural conditions	0/20
ICD-10: J984	Other disorders of lung	0/20

Neoplasm of the respiratory system

0100606

Female ⓘ

Male ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Female Show Male

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Female ^ⓘ

Male ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ