Statistics
| Female Case | Female Control | % Female |
|---|---|---|
| 137 | 249720 | 35% |
| Male Case | Male Control | % Male |
|---|---|---|
| 256 | 210081 | 65% |
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr4:174609693 | rs13132889 | - | T>G | 34 | 25430 | 28.31 | 1.033e-07 | 2.549 |
| chr2:56909573 | rs6732353 | - | C>T | 16 | 8431 | 28.13 | 1.135e-07 | 3.597 |
| chr11:76727237 | rs116973760 | ACER3 | A>G | 15 | 7611 | 26.82 | 2.238e-07 | 3.609 |
| chr13:19836289 | rs75256132 | - | C>T | 38 | 30429 | 26.06 | 3.315e-07 | 2.363 |
| chr1:194040018 | rs17550167 | - | G>A | 38 | 30738 | 25.3 | 4.895e-07 | 2.335 |
| chr5:76303699 | rs1035887 | - | C>T | 28 | 20072 | 25.08 | 5.5e-07 | 2.605 |
| chr8:66226442 | rs13277843 | - | C>T | 116 | 137195 | 25.05 | 5.575e-07 | 1.795 |
| chr13:98302186 | rs6491359 | - | A>C | 24 | 16037 | 24.9 | 6.024e-07 | 2.768 |
| chr3:87403681 | rs34759995 | - | A>G | 103 | 119622 | 24.88 | 6.109e-07 | 1.822 |
| chr13:108819705 | rs182303318 | - | G>A | 14 | 7118 | 24.74 | 6.545e-07 | 3.579 |
| chr12:6325952 | rs74881391 | CD9 | C>T | 13 | 6454 | 23.87 | 1.033e-06 | 3.649 |
| chr13:19894363 | rs78719366 | - | G>A | 37 | 30763 | 23.53 | 1.23e-06 | 2.29 |
| chr1:194884655 | rs78702938 | - | A>G | 12 | 5796 | 23.25 | 1.42e-06 | 3.756 |
| chr16:82920788 | rs76581745 | CDH13 | G>A | 12 | 5900 | 22.72 | 1.877e-06 | 3.707 |
| chr3:87404425 | rs4859062 | - | G>A | 62 | 62555 | 22.37 | 2.252e-06 | 1.94 |
| chr5:74491956 | rs59620469 | ANKRD31 | T>C | 15 | 8404 | 22.24 | 2.403e-06 | 3.257 |
| chr11:87986666 | rs12804675 | - | C>A | 48 | 44623 | 22.15 | 2.527e-06 | 2.066 |
| chr8:66278139 | rs10087366 | - | G>A | 95 | 110568 | 21.55 | 3.456e-06 | 1.767 |
| chr1:177274735 | rs35735655 | - | G>A | 16 | 9487 | 21.3 | 3.92e-06 | 3.085 |
| chr3:86988351 | rs116104226 | VGLL3 | G>A | 14 | 7725 | 21.2 | 4.147e-06 | 3.287 |
| chr11:76727237 | rs116973760 | ACER3 | A>G | 15 | 7454 | 29.54 | 5.49e-08 | 3.827 |
| chr5:76303699 | rs1035887 | - | C>T | 28 | 19437 | 29.14 | 6.72e-08 | 2.804 |
| chr16:25620784 | rs11863473 | - | G>A | 10 | 4085 | 26.97 | 2.071e-07 | 4.588 |
| chr12:6325952 | rs74881391 | CD9 | C>T | 13 | 6270 | 26.62 | 2.471e-07 | 3.899 |
| chr13:108819705 | rs182303318 | - | G>A | 14 | 7033 | 26.5 | 2.632e-07 | 3.731 |
| chr1:194884655 | rs78702938 | - | A>G | 12 | 5589 | 26.19 | 3.095e-07 | 4.04 |
| chr4:3943571 | rs73076826 | - | G>A | 11 | 4957 | 25.36 | 4.749e-07 | 4.168 |
| chr8:66226442 | rs13277843 | - | C>T | 104 | 124320 | 24.71 | 6.659e-07 | 1.84 |
| chr13:19836289 | rs75256132 | - | C>T | 36 | 29903 | 24.47 | 7.532e-07 | 2.36 |
| chr1:194040018 | rs17550167 | - | G>A | 34 | 28449 | 22.54 | 2.056e-06 | 2.328 |
| chr19:39663768 | rs35655056 | PAK4 | G>A | 18 | 11505 | 22.38 | 2.237e-06 | 3.0 |
| chr13:19894363 | rs78719366 | - | G>A | 35 | 30250 | 21.97 | 2.765e-06 | 2.283 |
| chr4:68410616 | rs115071032 | CENPC | C>T | 26 | 19905 | 21.63 | 3.309e-06 | 2.524 |
| chr3:87403681 | rs34759995 | - | A>G | 90 | 108100 | 21.49 | 3.55e-06 | 1.804 |
| chr2:59487982 | rs116918026 | - | C>T | 11 | 5321 | 21.3 | 3.932e-06 | 3.758 |
| chr4:40555815 | rs6839162 | RBM47 | G>C | 7 | 2642 | 21.27 | 3.982e-06 | 4.924 |
| chr7:47016392 | rs17172798 | - | C>A | 13 | 7150 | 21.22 | 4.085e-06 | 3.425 |
| chr10:125965713 | rs186468774 | - | G>T | 12 | 6356 | 21.0 | 4.589e-06 | 3.552 |
| chr3:127533724 | rs13075440 | MGLL | A>G | 87 | 103637 | 20.99 | 4.62e-06 | 1.803 |
| chr6:150161242 | rs11968879 | AL355312.6 | G>A | 8 | 3349 | 20.89 | 4.875e-06 | 4.473 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr8:30039023 | rs55810013 | DCTN6 | A>G | 85 | 39834 | 28.27 | 1.054e-07 | 1.855 |
| chr15:84527793 | rs117825563 | ADAMTSL3 | G>A | 20 | 5381 | 26.76 | 2.3e-07 | 3.068 |
| chr10:2458392 | rs115301761 | - | C>A | 20 | 5630 | 24.58 | 7.147e-07 | 2.939 |
| chr13:108470281 | rs77741808 | FAM155A | G>A | 18 | 4949 | 23.21 | 1.452e-06 | 3.005 |
| chr8:30089070 | rs2958746 | - | T>C | 79 | 38352 | 22.95 | 1.663e-06 | 1.777 |
| chr11:104160529 | rs11226274 | - | G>A | 294 | 193551 | 22.43 | 2.177e-06 | 1.501 |
| chr1:18709012 | rs78978085 | - | C>T | 19 | 5549 | 21.65 | 3.279e-06 | 2.831 |
| chr10:2458524 | rs79887572 | - | A>G | 20 | 6030 | 21.58 | 3.399e-06 | 2.761 |
| chr11:12485824 | rs61875564 | PARVA | A>G | 21 | 6475 | 21.3 | 3.922e-06 | 2.686 |
| chr14:33740086 | rs243308 | NPAS3 | C>T | 150 | 86534 | 21.09 | 4.384e-06 | 1.547 |
| chr6:92712489 | rs79102072 | - | G>A | 28 | 9929 | 20.58 | 5.716e-06 | 2.351 |
| chr22:33512106 | rs137307 | - | T>C | 110 | 59476 | 20.53 | 5.882e-06 | 1.614 |
| chr3:96178193 | rs7638197 | - | A>G | 74 | 36365 | 20.34 | 6.466e-06 | 1.745 |
| chr1:27332637 | rs151266984 | TENT5B | T>G | 19 | 5749 | 20.19 | 7.02e-06 | 2.739 |
| chr18:22547450 | rs78409076 | - | C>T | 24 | 8050 | 20.11 | 7.32e-06 | 2.474 |
| chr2:141650242 | rs12463802 | LRP1B | C>A | 260 | 169294 | 19.85 | 8.369e-06 | 1.46 |
| chr23:111503884 | rs145947939 | - | A>G | 14 | 3692 | 19.78 | 8.668e-06 | 3.181 |
| chr3:2743968 | rs115967245 | CNTN4 | A>C | 16 | 4498 | 19.66 | 9.254e-06 | 2.928 |
| chr14:81094189 | rs61981711 | CEP128 | T>C | 17 | 4944 | 19.64 | 9.358e-06 | 2.845 |
| chr8:30004493 | rs2341177 | LEPROTL1 | A>G | 73 | 36167 | 19.53 | 9.89e-06 | 1.732 |
| chr15:84527793 | rs117825563 | ADAMTSL3 | G>A | 20 | 5293 | 28.48 | 9.461e-08 | 3.173 |
| chr1:18709012 | rs78978085 | - | C>T | 19 | 5466 | 23.06 | 1.572e-06 | 2.923 |
| chr6:83053175 | rs76817065 | - | A>G | 30 | 10615 | 22.91 | 1.698e-06 | 2.396 |
| chr11:12485824 | rs61875564 | PARVA | A>G | 21 | 6386 | 22.72 | 1.878e-06 | 2.771 |
| chr6:92712489 | rs79102072 | - | G>A | 28 | 9729 | 22.51 | 2.092e-06 | 2.444 |
| chr6:110621332 | rs118099471 | METTL24 | C>T | 20 | 6003 | 22.21 | 2.444e-06 | 2.803 |
| chr21:23063411 | rs117612052 | - | C>T | 16 | 4303 | 22.09 | 2.598e-06 | 3.109 |
| chr6:82856248 | rs77113892 | - | C>T | 25 | 8382 | 21.74 | 3.12e-06 | 2.52 |
| chr10:89885149 | rs79044284 | - | A>G | 38 | 15240 | 21.37 | 3.794e-06 | 2.143 |
| chr22:33512106 | rs137307 | - | T>C | 103 | 55386 | 21.21 | 4.114e-06 | 1.653 |
| chr3:55326585 | rs73069561 | - | G>A | 37 | 14663 | 21.08 | 4.408e-06 | 2.151 |
| chr23:111503884 | rs145947939 | - | A>G | 14 | 3618 | 21.06 | 4.445e-06 | 3.295 |
| chr4:44700454 | rs77375257 | GUF1 | G>A | 28 | 10025 | 20.84 | 4.981e-06 | 2.367 |
| chr8:80951882 | rs118182320 | AC036214.3 | C>T | 16 | 4483 | 20.45 | 6.134e-06 | 2.989 |
| chr6:34940258 | rs78029704 | ANKS1A | T>C | 28 | 10088 | 20.42 | 6.221e-06 | 2.348 |
| chr8:30018355 | rs116975008 | LEPROTL1 | C>T | 19 | 5789 | 20.42 | 6.215e-06 | 2.757 |
| chr13:47726116 | rs77371590 | - | A>C | 22 | 7175 | 20.34 | 6.476e-06 | 2.582 |
| chr14:33740086 | rs243308 | NPAS3 | C>T | 140 | 81521 | 20.33 | 6.519e-06 | 1.559 |
| chr11:104160529 | rs11226274 | - | G>A | 273 | 183330 | 20.22 | 6.901e-06 | 1.493 |
| chr7:149934619 | rs112367402 | - | G>A | 34 | 13335 | 20.14 | 7.179e-06 | 2.177 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: D140 | Middle ear, nasal cavity and accessory sinuses | 3/20 |
| ID | Name | Top Correlation |
|---|