Vaginal hernia

0100672

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Sex Split

Interactive Plot

Statistics

Case	Control
22032	438162

Phenotype Definition

The presence of a hernia of the vagina. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr15:48426484	rs1426654	SLC24A5	A>G	853	26673	162.6	3.097e-37	0.6414
chr5:33951693	rs16891982	SLC45A2	G>C	2492	64566	156.5	6.445e-36	0.7695
chr25:2692710	rs2259750	-	A>G	7609	175262	151.8	7.06e-35	0.8534
chr23:71628912	rs3012642	AL133500.1	A>G	916	21808	145.3	1.869e-33	0.6649
chr5:33958959	rs28777	SLC45A2	A>C	2098	54894	140.8	1.764e-32	0.7638
chr15:48392165	rs1834640	-	A>G	1055	30569	136.1	1.85e-31	0.6923
chr23:128718936	rs2362937	OCRL	T>C	796	19155	132.5	1.136e-30	0.6588
chr25:154986418	rs142918084	-	C>G	1976	30973	128.7	8.021e-30	1.308
chr1:159174683	rs2814778	ACKR1	T>C	591	18786	120.4	5.159e-28	0.6329
chr19:42393286	rs717225	ARHGEF1	A>G	694	21249	118.5	1.318e-27	0.6569
chr5:54280007	rs1508890	ESM1	C>A	561	17855	114.4	1.084e-26	0.6329
chr2:136407479	rs1446585	R3HDM1	A>G	11544	254854	110.7	7.018e-26	0.8907
chr19:42392441	rs16975619	ARHGEF1	T>C	630	19380	110.3	8.61e-26	0.6538
chr10:31515132	rs2484990	-	C>T	752	22340	110.2	8.799e-26	0.677
chr6:136480972	rs9483910	PDE7B	C>T	684	20686	109.9	1.047e-25	0.6652
chr2:66725070	rs12995572	MEIS1	G>C	918	26233	108.8	1.756e-25	0.7032
chr5:33951116	rs35397	SLC45A2	T>G	3608	86500	107.9	2.788e-25	0.8321
chr10:31495974	rs1250307	-	A>G	743	22029	107.8	2.964e-25	0.6783
chr13:72463541	rs1460465	-	A>G	482	15642	107.4	3.702e-25	0.6205
chr25:2691012	rs142162416	-	A>G	2366	38738	107.4	3.611e-25	1.252
chr25:154986418	rs142918084	-	C>G	1902	28799	139.1	4.147e-32	1.33
chr25:2692710	rs2259750	-	A>G	7271	161331	105.9	7.761e-25	0.8733
chr25:155013081	rs146997510	-	T>A	928	25221	90.76	1.622e-21	0.7258
chr25:2691012	rs142162416	-	A>G	2329	38111	88.58	4.89e-21	1.229
chr25:2661556	rs73188900	-	A>C	605	17509	84.69	3.492e-20	0.6831
chr25:2682149	rs311128	-	C>T	2557	42504	82.03	1.341e-19	1.209
chr25:2685254	rs311142	-	C>T	16262	342131	81.29	1.947e-19	0.9128
chr25:2644302	rs1136470	-	C>T	6658	119156	80.64	2.713e-19	1.131
chr25:154999134	rs6642320	-	G>A	16320	307043	78.0	1.031e-18	1.095
chr25:154935282	rs112437556	-	C>T	1692	27129	76.9	1.798e-18	1.251
chr25:2645366	rs311083	-	C>G	15250	321306	75.83	3.086e-18	0.9143
chr25:2679949	rs311121	-	G>T	6877	123911	75.28	4.078e-18	1.124
chr25:154998312	rs306885	-	T>G	21774	414665	74.37	6.471e-18	1.088
chr25:155104608	rs5940618	-	G>A	8264	178769	69.12	9.26e-17	0.9012
chr25:155183483	rs73237015	-	G>A	8763	161179	64.01	1.236e-15	1.103
chr25:155016369	rs28425172	-	T>C	19406	403064	63.7	1.447e-15	0.9244
chr25:2676160	rs312232	-	C>T	10224	189374	63.43	1.666e-15	1.097
chr2:20878105	rs9306894	GDF7	A>G	16435	310887	61.01	5.684e-15	1.082
chr25:2677358	rs66607823	-	A>G	5008	89488	60.54	7.199e-15	1.127
chr25:155058865	rs73234550	-	G>A	1159	28852	58.16	2.414e-14	0.7936

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr15:48426484	rs1426654	SLC24A5	A>G	853	2313	202.6	5.697e-46	0.5659
chr23:71628912	rs3012642	AL133500.1	A>G	916	2066	190.2	2.871e-43	0.578
chr23:64367019	rs7064929	-	G>A	717	1701	181.0	2.904e-41	0.5506
chr23:128718936	rs2362937	OCRL	T>C	796	1808	169.1	1.148e-38	0.5754
chr1:159174683	rs2814778	ACKR1	T>C	591	1673	164.0	1.505e-37	0.5441
chr15:48392165	rs1834640	-	A>G	1055	2576	159.2	1.676e-36	0.629
chr19:42393286	rs717225	ARHGEF1	A>G	694	1852	153.3	3.342e-35	0.5772
chr5:33951693	rs16891982	SLC45A2	G>C	2492	5185	153.1	3.591e-35	0.7334
chr6:136480972	rs9483910	PDE7B	C>T	684	1822	150.1	1.62e-34	0.5782
chr23:106146349	rs5962774	MORC4	T>C	417	1095	149.4	2.29e-34	0.4995
chr19:42392441	rs16975619	ARHGEF1	T>C	630	1704	147.1	7.42e-34	0.5694
chr8:145639681	rs1871534	SLC39A4	G>C	564	1569	146.7	9.1e-34	0.5538
chr13:72441665	rs3759505	-	C>T	511	1458	145.8	1.442e-33	0.5403
chr23:63423664	rs5964740	AMER1	C>T	1083	2205	141.8	1.076e-32	0.6408
chr23:128902863	rs859585	XPNPEP2	G>A	1810	3355	141.7	1.124e-32	0.7019
chr23:63410110	rs61730681	AMER1	T>C	1084	2204	140.5	2.096e-32	0.6422
chr5:147863034	rs9325101	HTR4	A>G	507	1434	139.9	2.841e-32	0.5454
chr5:33958959	rs28777	SLC45A2	A>C	2098	4418	138.5	5.761e-32	0.7268
chr19:42391425	rs28521795	ARHGEF1	G>A	598	1610	137.3	1.034e-31	0.572
chr19:42392310	rs2288509	ARHGEF1	C>T	549	1511	136.8	1.331e-31	0.5602
chr12:114673421	rs1247943	-	A>G	21230	30850	46.32	1.004e-11	1.087
chr12:114666099	rs2555009	-	G>A	21214	30834	45.06	1.91e-11	1.086
chr25:2685254	rs311142	-	C>T	16262	26028	44.92	2.051e-11	0.9185
chr25:154986418	rs142918084	-	C>G	1902	2398	39.52	3.254e-10	1.218
chr12:114673774	rs2555015	-	T>C	20479	32377	38.22	6.315e-10	0.9268
chr12:114685571	rs1270884	-	G>A	21903	31995	37.64	8.514e-10	1.078
chr25:2661556	rs73188900	-	A>C	605	1233	36.42	1.588e-09	0.7401
chr2:20878105	rs9306894	GDF7	A>G	16435	23795	34.91	3.448e-09	1.078
chr25:2692710	rs2259750	-	A>G	7271	11931	32.59	1.137e-08	0.9107
chr25:2691012	rs142162416	-	A>G	2329	3042	31.94	1.59e-08	1.173
chr12:114683214	rs34388546	-	C>T	7897	12892	31.08	2.47e-08	0.9156
chr12:114677491	rs2555014	-	G>T	18396	29027	29.82	4.735e-08	0.9343
chr16:51488129	rs12325192	-	C>T	8283	13473	29.64	5.196e-08	0.9188
chr2:119313837	rs72826310	-	T>C	5375	7455	29.32	6.138e-08	1.109
chr2:119369740	rs72828753	-	C>T	5109	7076	28.59	8.944e-08	1.11
chr4:126975454	rs7678854	-	C>T	9818	14031	27.4	1.652e-07	1.081
chr25:2644302	rs1136470	-	C>T	6658	9350	27.37	1.681e-07	1.095
chr25:154999134	rs6642320	-	G>A	16320	23791	26.18	3.104e-07	1.069
chr12:114637848	rs4767234	-	A>C	17338	27355	26.04	3.343e-07	0.938
chr2:119437365	rs72830772	-	G>A	5057	7027	25.5	4.423e-07	1.104

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: N393	Stress incontinence	8/20
ICD: N811	Cystocele	8/20
ICD: N812	Incomplete uterovaginal prolapse	8/20
ICD: N813	Complete uterovaginal prolapse	1/20
ICD: N815	Vaginal enterocele	3/20
ICD: N816	Rectocele	12/20

ID	Name	Top Correlation
ICD-10: K561	Intussusception	0/20
ICD-10: K623	Rectal prolapse	0/20
ICD-10: M544	Lumbago with sciatica	0/20
ICD-10: N329	Bladder disorder, unspecified	0/20
ICD-10: N750	Cyst of Bartholin's gland	0/20
ICD-10: N814	Uterovaginal prolapse, unspecified	0/20
ICD-10: N818	Other female genital prolapse	0/20
ICD-10: N819	Female genital prolapse, unspecified	0/20
ICD-10: N842	Polyp of vagina	0/20
ICD-10: N993	Prolapse of vaginal vault after hysterectomy	0/20

Vaginal hernia

0100672

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ