Case | Control |
---|---|
22032 | 438162 |
The presence of a hernia of the vagina. [HPO:probinson]
Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
---|---|---|---|---|---|---|---|---|
chr15:48426484 | rs1426654 | SLC24A5 | A>G | 853 | 26673 | 162.6 | 3.097e-37 | 0.6414 |
chr5:33951693 | rs16891982 | SLC45A2 | G>C | 2492 | 64566 | 156.5 | 6.445e-36 | 0.7695 |
chr25:2692710 | rs2259750 | - | A>G | 7609 | 175262 | 151.8 | 7.06e-35 | 0.8534 |
chr23:71628912 | rs3012642 | AL133500.1 | A>G | 916 | 21808 | 145.3 | 1.869e-33 | 0.6649 |
chr5:33958959 | rs28777 | SLC45A2 | A>C | 2098 | 54894 | 140.8 | 1.764e-32 | 0.7638 |
chr15:48392165 | rs1834640 | - | A>G | 1055 | 30569 | 136.1 | 1.85e-31 | 0.6923 |
chr23:128718936 | rs2362937 | OCRL | T>C | 796 | 19155 | 132.5 | 1.136e-30 | 0.6588 |
chr25:154986418 | rs142918084 | - | C>G | 1976 | 30973 | 128.7 | 8.021e-30 | 1.308 |
chr1:159174683 | rs2814778 | ACKR1 | T>C | 591 | 18786 | 120.4 | 5.159e-28 | 0.6329 |
chr19:42393286 | rs717225 | ARHGEF1 | A>G | 694 | 21249 | 118.5 | 1.318e-27 | 0.6569 |
chr5:54280007 | rs1508890 | ESM1 | C>A | 561 | 17855 | 114.4 | 1.084e-26 | 0.6329 |
chr2:136407479 | rs1446585 | R3HDM1 | A>G | 11544 | 254854 | 110.7 | 7.018e-26 | 0.8907 |
chr19:42392441 | rs16975619 | ARHGEF1 | T>C | 630 | 19380 | 110.3 | 8.61e-26 | 0.6538 |
chr10:31515132 | rs2484990 | - | C>T | 752 | 22340 | 110.2 | 8.799e-26 | 0.677 |
chr6:136480972 | rs9483910 | PDE7B | C>T | 684 | 20686 | 109.9 | 1.047e-25 | 0.6652 |
chr2:66725070 | rs12995572 | MEIS1 | G>C | 918 | 26233 | 108.8 | 1.756e-25 | 0.7032 |
chr5:33951116 | rs35397 | SLC45A2 | T>G | 3608 | 86500 | 107.9 | 2.788e-25 | 0.8321 |
chr10:31495974 | rs1250307 | - | A>G | 743 | 22029 | 107.8 | 2.964e-25 | 0.6783 |
chr13:72463541 | rs1460465 | - | A>G | 482 | 15642 | 107.4 | 3.702e-25 | 0.6205 |
chr25:2691012 | rs142162416 | - | A>G | 2366 | 38738 | 107.4 | 3.611e-25 | 1.252 |
chr25:154986418 | rs142918084 | - | C>G | 1902 | 28799 | 139.1 | 4.147e-32 | 1.33 |
chr25:2692710 | rs2259750 | - | A>G | 7271 | 161331 | 105.9 | 7.761e-25 | 0.8733 |
chr25:155013081 | rs146997510 | - | T>A | 928 | 25221 | 90.76 | 1.622e-21 | 0.7258 |
chr25:2691012 | rs142162416 | - | A>G | 2329 | 38111 | 88.58 | 4.89e-21 | 1.229 |
chr25:2661556 | rs73188900 | - | A>C | 605 | 17509 | 84.69 | 3.492e-20 | 0.6831 |
chr25:2682149 | rs311128 | - | C>T | 2557 | 42504 | 82.03 | 1.341e-19 | 1.209 |
chr25:2685254 | rs311142 | - | C>T | 16262 | 342131 | 81.29 | 1.947e-19 | 0.9128 |
chr25:2644302 | rs1136470 | - | C>T | 6658 | 119156 | 80.64 | 2.713e-19 | 1.131 |
chr25:154999134 | rs6642320 | - | G>A | 16320 | 307043 | 78.0 | 1.031e-18 | 1.095 |
chr25:154935282 | rs112437556 | - | C>T | 1692 | 27129 | 76.9 | 1.798e-18 | 1.251 |
chr25:2645366 | rs311083 | - | C>G | 15250 | 321306 | 75.83 | 3.086e-18 | 0.9143 |
chr25:2679949 | rs311121 | - | G>T | 6877 | 123911 | 75.28 | 4.078e-18 | 1.124 |
chr25:154998312 | rs306885 | - | T>G | 21774 | 414665 | 74.37 | 6.471e-18 | 1.088 |
chr25:155104608 | rs5940618 | - | G>A | 8264 | 178769 | 69.12 | 9.26e-17 | 0.9012 |
chr25:155183483 | rs73237015 | - | G>A | 8763 | 161179 | 64.01 | 1.236e-15 | 1.103 |
chr25:155016369 | rs28425172 | - | T>C | 19406 | 403064 | 63.7 | 1.447e-15 | 0.9244 |
chr25:2676160 | rs312232 | - | C>T | 10224 | 189374 | 63.43 | 1.666e-15 | 1.097 |
chr2:20878105 | rs9306894 | GDF7 | A>G | 16435 | 310887 | 61.01 | 5.684e-15 | 1.082 |
chr25:2677358 | rs66607823 | - | A>G | 5008 | 89488 | 60.54 | 7.199e-15 | 1.127 |
chr25:155058865 | rs73234550 | - | G>A | 1159 | 28852 | 58.16 | 2.414e-14 | 0.7936 |
Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
---|---|---|---|---|---|---|---|---|
chr15:48426484 | rs1426654 | SLC24A5 | A>G | 853 | 2313 | 202.6 | 5.697e-46 | 0.5659 |
chr23:71628912 | rs3012642 | AL133500.1 | A>G | 916 | 2066 | 190.2 | 2.871e-43 | 0.578 |
chr23:64367019 | rs7064929 | - | G>A | 717 | 1701 | 181.0 | 2.904e-41 | 0.5506 |
chr23:128718936 | rs2362937 | OCRL | T>C | 796 | 1808 | 169.1 | 1.148e-38 | 0.5754 |
chr1:159174683 | rs2814778 | ACKR1 | T>C | 591 | 1673 | 164.0 | 1.505e-37 | 0.5441 |
chr15:48392165 | rs1834640 | - | A>G | 1055 | 2576 | 159.2 | 1.676e-36 | 0.629 |
chr19:42393286 | rs717225 | ARHGEF1 | A>G | 694 | 1852 | 153.3 | 3.342e-35 | 0.5772 |
chr5:33951693 | rs16891982 | SLC45A2 | G>C | 2492 | 5185 | 153.1 | 3.591e-35 | 0.7334 |
chr6:136480972 | rs9483910 | PDE7B | C>T | 684 | 1822 | 150.1 | 1.62e-34 | 0.5782 |
chr23:106146349 | rs5962774 | MORC4 | T>C | 417 | 1095 | 149.4 | 2.29e-34 | 0.4995 |
chr19:42392441 | rs16975619 | ARHGEF1 | T>C | 630 | 1704 | 147.1 | 7.42e-34 | 0.5694 |
chr8:145639681 | rs1871534 | SLC39A4 | G>C | 564 | 1569 | 146.7 | 9.1e-34 | 0.5538 |
chr13:72441665 | rs3759505 | - | C>T | 511 | 1458 | 145.8 | 1.442e-33 | 0.5403 |
chr23:63423664 | rs5964740 | AMER1 | C>T | 1083 | 2205 | 141.8 | 1.076e-32 | 0.6408 |
chr23:128902863 | rs859585 | XPNPEP2 | G>A | 1810 | 3355 | 141.7 | 1.124e-32 | 0.7019 |
chr23:63410110 | rs61730681 | AMER1 | T>C | 1084 | 2204 | 140.5 | 2.096e-32 | 0.6422 |
chr5:147863034 | rs9325101 | HTR4 | A>G | 507 | 1434 | 139.9 | 2.841e-32 | 0.5454 |
chr5:33958959 | rs28777 | SLC45A2 | A>C | 2098 | 4418 | 138.5 | 5.761e-32 | 0.7268 |
chr19:42391425 | rs28521795 | ARHGEF1 | G>A | 598 | 1610 | 137.3 | 1.034e-31 | 0.572 |
chr19:42392310 | rs2288509 | ARHGEF1 | C>T | 549 | 1511 | 136.8 | 1.331e-31 | 0.5602 |
chr12:114673421 | rs1247943 | - | A>G | 21230 | 30850 | 46.32 | 1.004e-11 | 1.087 |
chr12:114666099 | rs2555009 | - | G>A | 21214 | 30834 | 45.06 | 1.91e-11 | 1.086 |
chr25:2685254 | rs311142 | - | C>T | 16262 | 26028 | 44.92 | 2.051e-11 | 0.9185 |
chr25:154986418 | rs142918084 | - | C>G | 1902 | 2398 | 39.52 | 3.254e-10 | 1.218 |
chr12:114673774 | rs2555015 | - | T>C | 20479 | 32377 | 38.22 | 6.315e-10 | 0.9268 |
chr12:114685571 | rs1270884 | - | G>A | 21903 | 31995 | 37.64 | 8.514e-10 | 1.078 |
chr25:2661556 | rs73188900 | - | A>C | 605 | 1233 | 36.42 | 1.588e-09 | 0.7401 |
chr2:20878105 | rs9306894 | GDF7 | A>G | 16435 | 23795 | 34.91 | 3.448e-09 | 1.078 |
chr25:2692710 | rs2259750 | - | A>G | 7271 | 11931 | 32.59 | 1.137e-08 | 0.9107 |
chr25:2691012 | rs142162416 | - | A>G | 2329 | 3042 | 31.94 | 1.59e-08 | 1.173 |
chr12:114683214 | rs34388546 | - | C>T | 7897 | 12892 | 31.08 | 2.47e-08 | 0.9156 |
chr12:114677491 | rs2555014 | - | G>T | 18396 | 29027 | 29.82 | 4.735e-08 | 0.9343 |
chr16:51488129 | rs12325192 | - | C>T | 8283 | 13473 | 29.64 | 5.196e-08 | 0.9188 |
chr2:119313837 | rs72826310 | - | T>C | 5375 | 7455 | 29.32 | 6.138e-08 | 1.109 |
chr2:119369740 | rs72828753 | - | C>T | 5109 | 7076 | 28.59 | 8.944e-08 | 1.11 |
chr4:126975454 | rs7678854 | - | C>T | 9818 | 14031 | 27.4 | 1.652e-07 | 1.081 |
chr25:2644302 | rs1136470 | - | C>T | 6658 | 9350 | 27.37 | 1.681e-07 | 1.095 |
chr25:154999134 | rs6642320 | - | G>A | 16320 | 23791 | 26.18 | 3.104e-07 | 1.069 |
chr12:114637848 | rs4767234 | - | A>C | 17338 | 27355 | 26.04 | 3.343e-07 | 0.938 |
chr2:119437365 | rs72830772 | - | G>A | 5057 | 7027 | 25.5 | 4.423e-07 | 1.104 |