Statistics
| Case | Control |
|---|---|
| 23399 | 436795 |
Phenotype Definition
A benign or malignant neoplasm (tumour) originating in the vascular system. [HPO:probinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr23:64367019 | rs7064929 | - | G>A | 1053 | 16513 | 24.46 | 7.581e-07 | 1.173 |
| chr6:31557791 | rs11575839 | NCR3 | G>A | 1313 | 21261 | 24.34 | 8.082e-07 | 1.153 |
| chr6:31546980 | rs3093671 | - | G>A | 1221 | 19700 | 23.78 | 1.079e-06 | 1.157 |
| chr7:120173630 | rs802374 | KCND2 | G>A | 768 | 17055 | 23.58 | 1.2e-06 | 0.835 |
| chr23:150891499 | rs13047 | FATE1 | A>C | 2724 | 45538 | 23.05 | 1.577e-06 | 1.103 |
| chr16:6114071 | rs8045590 | RBFOX1 | A>C | 6492 | 114082 | 22.52 | 2.084e-06 | 1.067 |
| chr13:73921973 | rs7988001 | - | T>C | 5852 | 115393 | 22.09 | 2.608e-06 | 0.9351 |
| chr19:34094912 | rs12983481 | - | T>C | 13374 | 257724 | 22.08 | 2.618e-06 | 0.9524 |
| chr1:235076889 | rs72754144 | - | T>C | 9260 | 179960 | 21.68 | 3.228e-06 | 0.9465 |
| chr23:40306474 | rs59151655 | - | T>G | 904 | 14160 | 21.12 | 4.313e-06 | 1.173 |
| chr23:19209307 | rs960190 | - | T>C | 1479 | 24002 | 21.04 | 4.495e-06 | 1.133 |
| chr25:524669 | rs6645166 | - | G>A | 16079 | 307966 | 21.02 | 4.541e-06 | 0.955 |
| chr1:151104078 | rs4971004 | - | C>T | 19314 | 368706 | 20.9 | 4.829e-06 | 0.9577 |
| chr1:240249915 | rs1341816 | FMN2 | T>C | 7581 | 148074 | 20.79 | 5.119e-06 | 0.9433 |
| chr4:6304469 | rs1046325 | WFS1 | A>G | 4107 | 71310 | 20.21 | 6.925e-06 | 1.078 |
| chr2:144442150 | rs6708276 | ARHGAP15 | A>G | 17416 | 333090 | 20.08 | 7.41e-06 | 0.9577 |
| chr13:19653666 | rs12430571 | - | A>G | 4565 | 90497 | 20.06 | 7.51e-06 | 0.9312 |
| chr8:132002356 | rs79539044 | ADCY8 | C>T | 634 | 9828 | 20.05 | 7.556e-06 | 1.202 |
| chr6:31489644 | rs3132454 | - | A>G | 17538 | 317333 | 19.77 | 8.718e-06 | 1.044 |
| chr18:72342869 | rs3794944 | ZNF407 | T>G | 7894 | 153897 | 19.51 | 1.002e-05 | 0.9459 |
| chr6:396321 | rs12203592 | IRF4 | C>T | 10535 | 188380 | 23.43 | 1.294e-06 | 1.057 |
| chr18:72264473 | rs7505334 | - | T>C | 9590 | 187059 | 22.31 | 2.324e-06 | 0.946 |
| chr2:144442150 | rs6708276 | ARHGAP15 | A>G | 16556 | 318406 | 21.8 | 3.024e-06 | 0.9547 |
| chr5:56273400 | rs7736675 | - | C>T | 9257 | 180632 | 21.44 | 3.651e-06 | 0.9464 |
| chr18:72263590 | rs6566816 | - | A>G | 9601 | 187160 | 21.44 | 3.646e-06 | 0.9471 |
| chr6:31489644 | rs3132454 | - | A>G | 16394 | 297122 | 21.3 | 3.929e-06 | 1.047 |
| chr7:219031 | rs67904661 | FAM20C | A>G | 13805 | 249174 | 21.14 | 4.26e-06 | 1.049 |
| chr18:72342869 | rs3794944 | ZNF407 | T>G | 7386 | 144977 | 20.83 | 5.024e-06 | 0.9424 |
| chr5:56225769 | rs189695 | MIER3 | C>T | 11102 | 215286 | 20.68 | 5.425e-06 | 0.9506 |
| chr25:524669 | rs6645166 | - | G>A | 15281 | 293802 | 20.32 | 6.558e-06 | 0.9544 |
| chr8:132002356 | rs79539044 | ADCY8 | C>T | 613 | 9501 | 20.23 | 6.872e-06 | 1.207 |
| chr13:73921973 | rs7988001 | - | T>C | 5499 | 108721 | 20.05 | 7.54e-06 | 0.9362 |
| chr1:240249915 | rs1341816 | FMN2 | T>C | 7103 | 139350 | 20.03 | 7.609e-06 | 0.9426 |
| chr8:114801369 | rs75707456 | - | A>G | 1089 | 23277 | 19.69 | 9.12e-06 | 0.8701 |
| chr1:151104078 | rs4971004 | - | C>T | 18494 | 354245 | 19.65 | 9.313e-06 | 0.9579 |
| chr9:124867491 | rs117821317 | - | G>A | 1477 | 24566 | 19.03 | 1.288e-05 | 1.126 |
| chr19:34094912 | rs12983481 | - | T>C | 12613 | 243580 | 19.01 | 1.302e-05 | 0.9545 |
| chr7:12058208 | rs6956188 | - | G>A | 15719 | 284892 | 18.96 | 1.335e-05 | 1.045 |
| chr7:83792154 | rs73179366 | SEMA3A | C>T | 6926 | 135760 | 18.93 | 1.357e-05 | 0.9436 |
| chr2:144496336 | rs55886108 | ARHGAP15 | C>T | 17629 | 337954 | 18.78 | 1.467e-05 | 0.9584 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:31489644 | rs3132454 | - | A>G | 16394 | 179805 | 21.68 | 3.221e-06 | 1.048 |
| chr5:56273400 | rs7736675 | - | C>T | 9257 | 109389 | 20.82 | 5.052e-06 | 0.9463 |
| chr18:72264473 | rs7505334 | - | T>C | 9590 | 113158 | 20.48 | 6.02e-06 | 0.9474 |
| chr6:131763378 | rs2608903 | - | T>C | 18396 | 202208 | 20.15 | 7.15e-06 | 1.046 |
| chr23:9917545 | rs17321225 | - | C>T | 1612 | 16156 | 20.07 | 7.456e-06 | 1.127 |
| chr18:72263590 | rs6566816 | - | A>G | 9601 | 113210 | 19.52 | 9.948e-06 | 0.9487 |
| chr19:34094912 | rs12983481 | - | T>C | 12613 | 147666 | 19.51 | 1.002e-05 | 0.9532 |
| chr18:72342869 | rs3794944 | ZNF407 | T>G | 7386 | 87727 | 19.41 | 1.053e-05 | 0.9435 |
| chr7:219031 | rs67904661 | FAM20C | A>G | 13805 | 151040 | 19.37 | 1.077e-05 | 1.048 |
| chr25:524669 | rs6645166 | - | G>A | 15281 | 177989 | 19.18 | 1.192e-05 | 0.955 |
| chr7:148335417 | rs73158206 | - | T>C | 1900 | 23784 | 19.07 | 1.258e-05 | 0.8992 |
| chr5:56225769 | rs189695 | MIER3 | C>T | 11102 | 130263 | 19.05 | 1.273e-05 | 0.9518 |
| chr1:247863666 | rs12144246 | - | G>A | 5884 | 62942 | 18.7 | 1.532e-05 | 1.065 |
| chr3:2770970 | rs71311721 | CNTN4 | C>T | 4095 | 43268 | 18.69 | 1.538e-05 | 1.077 |
| chr2:144442150 | rs6708276 | ARHGAP15 | A>G | 16556 | 192489 | 18.57 | 1.635e-05 | 0.9574 |
| chr3:163312168 | rs73161816 | - | C>A | 3680 | 38784 | 18.3 | 1.888e-05 | 1.08 |
| chr12:27693851 | rs306657 | PPFIBP1 | A>T | 22326 | 257822 | 18.1 | 2.097e-05 | 0.9597 |
| chr7:94316261 | rs77235809 | - | T>G | 1073 | 13869 | 18.08 | 2.117e-05 | 0.8726 |
| chr8:132002356 | rs79539044 | ADCY8 | C>T | 613 | 5793 | 18.08 | 2.114e-05 | 1.199 |
| chr13:73921973 | rs7988001 | - | T>C | 5499 | 65698 | 17.95 | 2.271e-05 | 0.9386 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: E349 | Endocrine disorder, unspecified | 1/20 |
| ICD: M75 | Shoulder lesions | 2/20 |
| ICD: R590 | Localised enlarged lymph nodes | 2/20 |