Statistics
| Case | Control |
|---|---|
| 15638 | 444556 |
Phenotype Definition
An abnormal connection between the gut and another hollow organ, such as the bladder, urethra, vagina, or other regions of the gastrointestinal tract. [HPO:probinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr16:86767505 | rs451300 | - | T>G | 2937 | 75399 | 26.44 | 2.718e-07 | 1.107 |
| chr12:25065729 | rs60503566 | BCAT1 | A>G | 3673 | 95494 | 26.06 | 3.302e-07 | 1.095 |
| chr12:25092929 | rs72640141 | BCAT1 | A>T | 3505 | 90832 | 25.92 | 3.558e-07 | 1.097 |
| chr18:47344725 | rs1942417 | AC090227.2 | C>A | 7641 | 204317 | 25.36 | 4.754e-07 | 1.069 |
| chr9:79246547 | rs11144986 | GCNT1 | T>C | 570 | 13012 | 24.66 | 6.831e-07 | 1.239 |
| chr2:86568446 | rs113998176 | - | G>A | 935 | 22406 | 24.18 | 8.78e-07 | 1.181 |
| chr9:79251004 | rs2067501 | GCNT1 | C>T | 489 | 11068 | 22.82 | 1.775e-06 | 1.248 |
| chr13:73461639 | rs61967073 | PIBF1 | C>T | 2338 | 72452 | 22.22 | 2.438e-06 | 0.9023 |
| chr2:120458052 | rs922619 | - | G>A | 14466 | 419242 | 21.9 | 2.867e-06 | 0.9488 |
| chr11:114918590 | rs36105682 | - | A>G | 2277 | 58240 | 21.54 | 3.472e-06 | 1.108 |
| chr23:78809754 | rs59936200 | - | G>A | 5794 | 150743 | 21.27 | 3.982e-06 | 1.072 |
| chr20:60968596 | rs1570027 | CABLES2 | A>G | 7210 | 212961 | 20.65 | 5.524e-06 | 0.9404 |
| chr15:33022090 | rs35330276 | GREM1 | G>A | 6574 | 175912 | 20.58 | 5.721e-06 | 1.066 |
| chr4:131925652 | rs62317717 | - | A>G | 4772 | 142859 | 20.39 | 6.327e-06 | 0.9307 |
| chr12:11895194 | rs2724641 | ETV6 | A>G | 857 | 20685 | 20.06 | 7.517e-06 | 1.171 |
| chr5:40831202 | rs192219 | RPL37 | C>T | 9714 | 263205 | 20.01 | 7.702e-06 | 1.056 |
| chr18:68607187 | rs79513401 | - | G>T | 815 | 26838 | 19.8 | 8.586e-06 | 0.8521 |
| chr6:168451501 | rs225761 | - | A>G | 7835 | 211081 | 19.79 | 8.626e-06 | 1.06 |
| chr5:136191651 | rs62387267 | - | G>A | 500 | 17192 | 19.74 | 8.865e-06 | 0.8165 |
| chr1:113721397 | rs946218 | - | A>G | 7424 | 199629 | 19.46 | 1.026e-05 | 1.061 |
| chr18:47344725 | rs1942417 | AC090227.2 | C>A | 7332 | 197297 | 27.23 | 1.803e-07 | 1.074 |
| chr18:46453463 | rs4939827 | SMAD7 | T>C | 14475 | 424203 | 24.25 | 8.456e-07 | 0.9447 |
| chr2:120458052 | rs922619 | - | G>A | 13320 | 390271 | 22.65 | 1.947e-06 | 0.9461 |
| chr2:86568446 | rs113998176 | - | G>A | 876 | 21308 | 21.09 | 4.392e-06 | 1.174 |
| chr8:2005649 | rs117874764 | MYOM2 | A>G | 489 | 11329 | 19.94 | 8.005e-06 | 1.231 |
| chr20:60968596 | rs1570027 | CABLES2 | A>G | 6741 | 201015 | 19.62 | 9.472e-06 | 0.9399 |
| chr5:40831202 | rs192219 | RPL37 | C>T | 9098 | 248524 | 19.55 | 9.823e-06 | 1.058 |
| chr1:113708305 | rs12127119 | - | T>C | 5256 | 141142 | 19.33 | 1.101e-05 | 1.07 |
| chr16:86767505 | rs451300 | - | T>G | 2487 | 64837 | 19.33 | 1.099e-05 | 1.098 |
| chr13:73461639 | rs61967073 | PIBF1 | C>T | 2293 | 71296 | 19.31 | 1.112e-05 | 0.9076 |
| chr15:33022090 | rs35330276 | GREM1 | G>A | 6115 | 165107 | 19.23 | 1.158e-05 | 1.066 |
| chr16:73996573 | rs2189610 | - | T>C | 10083 | 297249 | 19.12 | 1.229e-05 | 0.9476 |
| chr19:14625790 | rs7003 | DNAJB1 | G>A | 4332 | 131025 | 18.96 | 1.335e-05 | 0.9301 |
| chr12:25065729 | rs60503566 | BCAT1 | A>G | 3070 | 80972 | 18.87 | 1.397e-05 | 1.088 |
| chr1:113659065 | rs10541977 | LRIG2 | A>ACT | 5239 | 140884 | 18.81 | 1.445e-05 | 1.069 |
| chr7:23934657 | rs62468328 | - | A>C | 13865 | 383304 | 18.61 | 1.605e-05 | 1.051 |
| chr18:47375932 | rs488890 | MYO5B | C>G | 15572 | 431462 | 18.55 | 1.655e-05 | 1.051 |
| chr18:47374429 | rs530576 | MYO5B | A>G | 15569 | 431982 | 18.44 | 1.757e-05 | 1.051 |
| chr18:47310917 | rs2678716 | ACAA2 | T>G | 13582 | 396735 | 18.39 | 1.798e-05 | 0.9514 |
| chr1:113721397 | rs946218 | - | A>G | 7031 | 190845 | 18.36 | 1.833e-05 | 1.061 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr18:47344725 | rs1942417 | AC090227.2 | C>A | 7332 | 61832 | 25.86 | 3.679e-07 | 1.074 |
| chr2:120458052 | rs922619 | - | G>A | 13320 | 122562 | 23.37 | 1.338e-06 | 0.9433 |
| chr18:47310917 | rs2678716 | ACAA2 | T>G | 13582 | 124786 | 21.15 | 4.249e-06 | 0.9461 |
| chr18:68607187 | rs79513401 | - | G>T | 800 | 8412 | 20.46 | 6.083e-06 | 0.8442 |
| chr16:86767505 | rs451300 | - | T>G | 2487 | 20232 | 19.91 | 8.104e-06 | 1.104 |
| chr18:47375932 | rs488890 | MYO5B | C>G | 15572 | 135034 | 19.77 | 8.736e-06 | 1.054 |
| chr18:47374429 | rs530576 | MYO5B | A>G | 15569 | 135241 | 19.48 | 1.017e-05 | 1.054 |
| chr2:86568446 | rs113998176 | - | G>A | 876 | 6685 | 19.34 | 1.092e-05 | 1.174 |
| chr19:14625790 | rs7003 | DNAJB1 | G>A | 4332 | 41202 | 19.31 | 1.111e-05 | 0.9271 |
| chr20:11754341 | rs6134351 | - | C>A | 2332 | 22780 | 18.87 | 1.397e-05 | 0.9065 |
| chr10:3324968 | rs76759835 | - | C>T | 519 | 3791 | 18.47 | 1.726e-05 | 1.224 |
| chr21:44582440 | rs8127377 | - | G>A | 13346 | 122538 | 18.36 | 1.826e-05 | 0.9496 |
| chr6:31838713 | rs494620 | SLC44A4 | G>A | 12203 | 105340 | 18.25 | 1.936e-05 | 1.054 |
| chr19:14608008 | rs8104397 | - | T>G | 5789 | 54419 | 18.16 | 2.033e-05 | 0.9368 |
| chr10:83951341 | rs17729611 | NRG3 | G>A | 504 | 3682 | 17.85 | 2.393e-05 | 1.224 |
| chr10:98903609 | rs55656826 | SLIT1 | T>C | 3805 | 31686 | 17.85 | 2.392e-05 | 1.08 |
| chr9:10416736 | rs6474548 | PTPRD | A>G | 5734 | 53891 | 17.75 | 2.516e-05 | 0.9372 |
| chr8:2005649 | rs117874764 | MYOM2 | A>G | 489 | 3566 | 17.62 | 2.694e-05 | 1.226 |
| chr16:3880659 | rs12447449 | CREBBP | A>G | 1618 | 12954 | 17.57 | 2.768e-05 | 1.12 |
| chr17:42572299 | rs77247037 | GPATCH8 | C>T | 465 | 3382 | 17.28 | 3.219e-05 | 1.23 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|