Neoplasm of the large intestine

0100834

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Links

Sex Split

Interactive Plot

Statistics

Case	Control
36878	423316

Phenotype Definition

The presence of a neoplasm of the large intestine. [HPO:probinson]

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr5:33951693	rs16891982	SLC45A2	G>C	4316	62742	211.2	7.676e-48	0.7906
chr5:33958959	rs28777	SLC45A2	A>C	3657	53335	182.6	1.339e-41	0.7896
chr18:46453463	rs4939827	SMAD7	T>C	35822	440281	178.2	1.171e-40	0.9043
chr15:48426484	rs1426654	SLC24A5	A>G	1623	25903	156.0	8.437e-36	0.7249
chr20:60968596	rs1570027	CABLES2	A>G	16004	204167	155.0	1.387e-35	0.8914
chr15:33022090	rs35330276	GREM1	G>A	15668	166818	147.0	7.887e-34	1.12
chr20:60921044	rs4925386	LAMA5	C>T	23652	294579	142.7	6.846e-33	0.9075
chr20:60958651	rs11699160	-	T>C	26847	332844	142.7	6.991e-33	0.9102
chr15:48392165	rs1834640	-	A>G	1947	29677	136.5	1.532e-31	0.7588
chr5:33955326	rs35390	SLC45A2	A>C	2653	38494	124.4	6.793e-29	0.7966
chr5:33955673	rs35391	SLC45A2	C>T	2642	38338	123.9	8.837e-29	0.7966
chr20:60920700	rs6143035	LAMA5	T>C	17711	222685	123.9	9.03e-29	0.9057
chr5:33951116	rs35397	SLC45A2	T>G	6278	83830	118.8	1.173e-27	0.8618
chr1:159174683	rs2814778	ACKR1	T>C	1129	18248	116.7	3.418e-27	0.7173
chr5:147671850	rs7724380	-	G>A	1200	18983	107.9	2.859e-25	0.7331
chr20:60899182	rs11698080	LAMA5	C>T	15804	198259	106.9	4.746e-25	0.9081
chr9:117110112	Affx-52344420	AKNA	T>TG	818	13761	106.4	6.12e-25	0.69
chr6:3185712	rs7754077	-	C>T	1101	17571	105.0	1.198e-24	0.7266
chr20:60898244	rs57627107	LAMA5	A>G	16478	206554	104.8	1.363e-24	0.9106
chr5:147863034	rs9325101	HTR4	A>G	969	15771	104.4	1.64e-24	0.7126
chr15:33022090	rs35330276	GREM1	G>A	14953	156269	148.6	3.576e-34	1.124
chr20:60968596	rs1570027	CABLES2	A>G	15326	192430	147.8	5.211e-34	0.8916
chr18:46453463	rs4939827	SMAD7	T>C	33637	405041	135.5	2.592e-31	0.9141
chr15:32994756	rs4779584	-	C>T	15136	159039	133.0	8.897e-31	1.116
chr20:60920700	rs6143035	LAMA5	T>C	16898	209677	126.1	2.882e-29	0.9027
chr20:60899182	rs11698080	LAMA5	C>T	15112	186988	108.1	2.586e-25	0.9056
chr20:60898244	rs57627107	LAMA5	A>G	15758	194877	106.6	5.425e-25	0.9079
chr20:60921044	rs4925386	LAMA5	C>T	22025	268044	103.3	2.91e-24	0.9184
chr20:60958651	rs11699160	-	T>C	24964	302654	102.3	4.692e-24	0.9212
chr15:33066195	rs75798403	FMN1	C>A	10422	109347	88.13	6.125e-21	1.109
chr15:32992658	rs28399071	-	G>A	7596	78495	84.38	4.085e-20	1.123
chr8:117630683	rs16892766	-	A>C	6480	66632	77.71	1.196e-18	1.127
chr20:60986019	rs2236200	RBBP8NL	A>C	18118	220187	73.68	9.194e-18	0.9264
chr11:111171709	rs3802842	COLCA2	A>C	23314	254829	72.77	1.458e-17	1.073
chr11:111165009	rs7103178	-	T>C	23358	255435	71.73	2.474e-17	1.073
chr20:60899206	rs2427283	LAMA5	T>C	21865	263456	68.87	1.05e-16	0.9326
chr8:117640315	rs11986063	-	C>T	7031	73355	64.13	1.166e-15	1.111
chr18:46453754	rs35352860	SMAD7	C>T	18771	226752	62.79	2.305e-15	0.9326
chr8:128413305	rs6983267	POU5F1B	G>T	34461	408300	61.71	3.985e-15	0.9413
chr20:60894470	rs2297588	LAMA5	C>T	22416	269044	60.56	7.12e-15	0.9371

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds ratio
chr20:60968596	rs1570027	CABLES2	A>G	15326	51421	136.4	1.661e-31	0.8859
chr15:33022090	rs35330276	GREM1	G>A	14953	41349	131.8	1.665e-30	1.13
chr20:60920700	rs6143035	LAMA5	T>C	16898	55955	114.6	9.463e-27	0.8982
chr15:32994756	rs4779584	-	C>T	15136	42166	114.1	1.249e-26	1.12
chr18:46453463	rs4939827	SMAD7	T>C	33637	107679	110.1	9.469e-26	0.9144
chr20:60921044	rs4925386	LAMA5	C>T	22025	71645	101.9	5.912e-24	0.911
chr20:60958651	rs11699160	-	T>C	24964	80738	95.89	1.214e-22	0.9161
chr20:60898244	rs57627107	LAMA5	A>G	15758	51963	93.88	3.347e-22	0.905
chr20:60899182	rs11698080	LAMA5	C>T	15112	49721	88.76	4.46e-21	0.9059
chr8:117630683	rs16892766	-	A>C	6480	17383	85.45	2.382e-20	1.151
chr15:33066195	rs75798403	FMN1	C>A	10422	29006	74.8	5.208e-18	1.112
chr15:32992658	rs28399071	-	G>A	7596	20810	71.67	2.543e-17	1.127
chr20:60986019	rs2236200	RBBP8NL	A>C	18118	58805	71.26	3.137e-17	0.9205
chr8:117640315	rs11986063	-	C>T	7031	19215	68.6	1.207e-16	1.129
chr20:60899206	rs2427283	LAMA5	T>C	21865	70223	63.36	1.72e-15	0.9289
chr11:111171709	rs3802842	COLCA2	A>C	23314	67647	62.82	2.261e-15	1.075
chr11:111165009	rs7103178	-	T>C	23358	67819	61.77	3.853e-15	1.075
chr18:46453754	rs35352860	SMAD7	C>T	18771	60415	56.24	6.409e-14	0.9298
chr15:33005875	rs1534594	-	C>T	35701	105472	53.7	2.33e-13	1.064
chr10:8701219	rs10795668	-	G>A	23154	73852	50.81	1.017e-12	0.9371

Associated Diseases ^ⓘ

ID	Name	Top Correlation
ICD: C787	Secondary malignant neoplasm of liver	5/20
ICD: D122	Ascending colon	1/20
ICD: D125	Sigmoid colon	7/20
ICD: D126	Colon, unspecified	3/20
ICD: D128	Rectum	7/20
ICD: K621	Rectal polyp	12/20
ICD: K635	Polyp of colon	14/20
ICD: M88	Paget's disease of bone [osteitis deformans]	1/20

ID	Name	Top Correlation
ICD-10: C182	Ascending colon	0/20
ICD-10: C185	Splenic flexure	0/20
ICD-10: C187	Sigmoid colon	0/20
ICD-10: C189	Colon, unspecified	0/20
ICD-10: C19	Malignant neoplasm of rectosigmoid junction	0/20
ICD-10: C211	Anal canal	0/20
ICD-10: C770	Lymph nodes of head, face and neck	0/20
ICD-10: C778	Lymph nodes of multiple regions	0/20
ICD-10: C779	Lymph node, unspecified	0/20
ICD-10: C781	Secondary malignant neoplasm of mediastinum	0/20
ICD-10: C796	Secondary malignant neoplasm of ovary	0/20
ICD-10: D374	Colon	0/20
ICD-10: D375	Rectum	0/20
ICD-10: F430	Acute stress reaction	0/20

Neoplasm of the large intestine

0100834

Normal Case/Contol ⓘ

Sibling Case/Control ⓘ

Links

Statistics

Phenotype Definition

Top SNP Information Show Normal Table Show Sibling SNP

Associated Diseases ⓘ Shared SNP diseases No shared SNP diseases

Normal Case/Contol ^ⓘ

Sibling Case/Control ^ⓘ

Top SNP Information

Associated Diseases ^ⓘ