Statistics
| Case | Control |
|---|---|
| 7984 | 452210 |
Phenotype Definition
An abnormality of the palm, that is, of the front of the hand. [HPO:probinson]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr5:1315660 | rs4975616 | - | A>G | 6757 | 404059 | 26.02 | 3.386e-07 | 0.9223 |
| chr6:28304841 | rs723475 | ZSCAN31 | T>G | 629 | 43653 | 25.09 | 5.463e-07 | 0.8149 |
| chr6:28302884 | rs1416919 | ZSCAN31 | T>G | 631 | 43729 | 24.92 | 5.991e-07 | 0.8157 |
| chr19:8269439 | rs72997309 | - | C>T | 1769 | 89967 | 24.84 | 6.231e-07 | 1.135 |
| chr6:28302113 | rs16893973 | ZSCAN31 | C>T | 631 | 43696 | 24.71 | 6.659e-07 | 0.8164 |
| chr6:28302278 | rs16893975 | ZSCAN31 | T>C | 631 | 43598 | 24.13 | 9.011e-07 | 0.8184 |
| chr21:19126079 | rs7276293 | - | T>C | 380 | 27792 | 24.04 | 9.44e-07 | 0.7746 |
| chr1:17476831 | rs12085482 | - | A>G | 103 | 9445 | 23.86 | 1.034e-06 | 0.6182 |
| chr5:9203914 | rs1805972 | SEMA5A | T>C | 515 | 36159 | 23.05 | 1.582e-06 | 0.8058 |
| chr5:163052317 | rs11949278 | - | T>C | 2294 | 143416 | 22.45 | 2.154e-06 | 0.8983 |
| chr15:98437293 | rs72754617 | - | G>A | 922 | 45098 | 22.39 | 2.229e-06 | 1.176 |
| chr12:76045936 | rs73187040 | - | G>A | 2869 | 151009 | 22.24 | 2.404e-06 | 1.103 |
| chr17:15364293 | rs2875140 | CDRT4 | G>A | 910 | 60388 | 22.02 | 2.698e-06 | 0.8513 |
| chr15:78723082 | rs2656057 | - | C>T | 192 | 15298 | 21.81 | 3.009e-06 | 0.7121 |
| chr5:152564299 | rs17501895 | - | C>T | 6172 | 368803 | 21.73 | 3.134e-06 | 0.9274 |
| chr16:82280093 | rs8051215 | - | T>C | 4772 | 287936 | 21.45 | 3.627e-06 | 0.9231 |
| chr8:78735245 | rs13249086 | - | C>T | 1251 | 62848 | 21.07 | 4.438e-06 | 1.146 |
| chr3:111515326 | rs58651217 | PLCXD2 | C>A | 358 | 25945 | 21.04 | 4.502e-06 | 0.7818 |
| chr6:28264681 | rs3800324 | PGBD1 | G>A | 649 | 44138 | 20.84 | 4.996e-06 | 0.8321 |
| chr6:28294888 | rs4711167 | ZSCAN31 | T>C | 654 | 44413 | 20.73 | 5.301e-06 | 0.833 |
| chr5:1315660 | rs4975616 | - | A>G | 6412 | 380814 | 24.54 | 7.291e-07 | 0.9225 |
| chr12:76045936 | rs73187040 | - | G>A | 2801 | 146346 | 22.28 | 2.36e-06 | 1.104 |
| chr12:58766772 | rs112106612 | - | C>T | 455 | 20803 | 21.17 | 4.208e-06 | 1.247 |
| chr2:2228745 | rs17247281 | MYT1L | C>G | 766 | 36966 | 20.18 | 7.066e-06 | 1.183 |
| chr5:24867580 | rs1353064 | - | C>T | 2799 | 146815 | 19.77 | 8.745e-06 | 1.098 |
| chr1:173190901 | rs115292553 | - | G>A | 230 | 9723 | 19.63 | 9.403e-06 | 1.345 |
| chr12:12031894 | rs2855712 | ETV6 | G>C | 5842 | 346387 | 19.58 | 9.652e-06 | 0.9292 |
| chr21:29495371 | rs75753005 | - | G>C | 524 | 24541 | 19.37 | 1.076e-05 | 1.218 |
| chr15:98437293 | rs72754617 | - | G>A | 893 | 43774 | 19.25 | 1.146e-05 | 1.165 |
| chr18:60004253 | rs7237982 | TNFRSF11A | A>G | 3999 | 213245 | 19.21 | 1.174e-05 | 1.084 |
| chr6:28302884 | rs1416919 | ZSCAN31 | T>G | 533 | 36362 | 19.03 | 1.286e-05 | 0.8242 |
| chr6:28302113 | rs16893973 | ZSCAN31 | C>T | 533 | 36331 | 18.88 | 1.394e-05 | 0.8249 |
| chr3:93965012 | rs66877608 | - | G>C | 1709 | 106614 | 18.87 | 1.397e-05 | 0.8939 |
| chr5:1322087 | rs401681 | CLPTM1L | C>T | 6725 | 396773 | 18.87 | 1.398e-05 | 0.9321 |
| chr19:8269439 | rs72997309 | - | C>T | 1692 | 86592 | 18.69 | 1.538e-05 | 1.119 |
| chr6:80965108 | rs117964117 | BCKDHB | T>C | 657 | 43926 | 18.67 | 1.552e-05 | 0.8408 |
| chr6:28304841 | rs723475 | ZSCAN31 | T>G | 533 | 36292 | 18.58 | 1.631e-05 | 0.8261 |
| chr19:52973262 | rs1112889 | ZNF578 | A>G | 602 | 28661 | 18.53 | 1.676e-05 | 1.198 |
| chr18:73494104 | rs17224239 | - | C>T | 2098 | 108683 | 18.52 | 1.679e-05 | 1.107 |
| chr1:212913168 | rs2271148 | NSL1 | T>C | 1385 | 70200 | 18.44 | 1.753e-05 | 1.13 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr12:12031894 | rs2855712 | ETV6 | G>C | 5842 | 65182 | 22.9 | 1.71e-06 | 0.9211 |
| chr3:93965012 | rs66877608 | - | G>C | 1709 | 20156 | 21.51 | 3.528e-06 | 0.8835 |
| chr12:58766772 | rs112106612 | - | C>T | 455 | 3852 | 21.36 | 3.807e-06 | 1.261 |
| chr19:52973262 | rs1112889 | ZNF578 | A>G | 602 | 5253 | 21.33 | 3.87e-06 | 1.224 |
| chr5:1315660 | rs4975616 | - | A>G | 6412 | 71110 | 20.64 | 5.549e-06 | 0.9262 |
| chr19:41333441 | rs4803378 | AC008537.1 | G>A | 274 | 3831 | 20.21 | 6.925e-06 | 0.7537 |
| chr2:119888630 | rs78780094 | - | C>T | 662 | 5870 | 19.72 | 8.977e-06 | 1.204 |
| chr1:173190901 | rs115292553 | - | G>A | 230 | 1794 | 19.64 | 9.354e-06 | 1.365 |
| chr19:52938361 | rs11084161 | ZNF534 | A>C | 608 | 5354 | 19.59 | 9.611e-06 | 1.213 |
| chr1:176824051 | rs2223488 | - | G>A | 493 | 4252 | 19.4 | 1.062e-05 | 1.237 |
| chr13:50656582 | rs2066575 | - | T>A | 4185 | 41689 | 19.34 | 1.095e-05 | 1.086 |
| chr19:36448842 | rs4806238 | - | C>T | 449 | 3829 | 19.09 | 1.248e-05 | 1.247 |
| chr15:98437293 | rs72754617 | - | G>A | 893 | 8152 | 19.0 | 1.304e-05 | 1.171 |
| chr19:52941618 | rs1366258 | ZNF534 | C>A | 577 | 5068 | 18.92 | 1.361e-05 | 1.214 |
| chr5:24867580 | rs1353064 | - | C>T | 2799 | 27439 | 18.86 | 1.407e-05 | 1.1 |
| chr12:76045936 | rs73187040 | - | G>A | 2801 | 27488 | 18.79 | 1.457e-05 | 1.099 |
| chr9:16779009 | rs6475079 | BNC2 | G>A | 1408 | 13306 | 18.56 | 1.646e-05 | 1.135 |
| chr6:164466266 | rs117308245 | - | G>A | 384 | 3238 | 18.47 | 1.727e-05 | 1.264 |
| chr6:80965108 | rs117964117 | BCKDHB | T>C | 657 | 8244 | 18.47 | 1.729e-05 | 0.8371 |
| chr2:2228745 | rs17247281 | MYT1L | C>G | 766 | 6923 | 18.46 | 1.736e-05 | 1.182 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: L720 | Epidermal cyst | 1/20 |