Statistics
| Case | Control |
|---|---|
| 371 | 459823 |
Phenotype Definition
A hemangioma, a benign tumor of the vascular endothelial cells, that is located in the vulva. [PMID:29980161]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:32626249 | rs6928482 | - | T>C | 429 | 450025 | 31.54 | 1.957e-08 | 1.503 |
| chr6:32546696 | rs3208409 | HLA-DRB1 | G>A | 330 | 332696 | 29.46 | 5.721e-08 | 1.485 |
| chr6:32546879 | Affx-28486470 | HLA-DRB1 | A>G | 331 | 333132 | 29.05 | 7.053e-08 | 1.48 |
| chr6:32492866 | rs111834747 | HLA-DRB5 | C>T | 325 | 326886 | 28.85 | 7.827e-08 | 1.483 |
| chr6:32546557 | rs34839759 | HLA-DRB1 | C>G | 330 | 331260 | 28.78 | 8.092e-08 | 1.477 |
| chr6:32560934 | rs28366302 | - | G>C | 331 | 333664 | 28.7 | 8.448e-08 | 1.476 |
| chr6:32434349 | rs9268969 | - | C>T | 336 | 342493 | 27.42 | 1.635e-07 | 1.463 |
| chr6:32550550 | rs28724008 | HLA-DRB1 | C>G | 335 | 341127 | 26.93 | 2.104e-07 | 1.457 |
| chr6:32637016 | rs9274697 | - | A>G | 436 | 466408 | 26.66 | 2.427e-07 | 1.457 |
| chr6:32432835 | rs9268923 | - | C>T | 334 | 342001 | 26.5 | 2.631e-07 | 1.454 |
| chr6:32433167 | rs2395185 | - | G>T | 332 | 337879 | 26.34 | 2.856e-07 | 1.453 |
| chr6:32657543 | rs4642516 | - | G>T | 436 | 467392 | 26.17 | 3.123e-07 | 1.451 |
| chr6:32429643 | rs9268853 | - | T>C | 333 | 340915 | 25.63 | 4.126e-07 | 1.446 |
| chr1:146849017 | rs4448568 | - | A>T | 211 | 200248 | 24.46 | 7.601e-07 | 1.489 |
| chr3:141370583 | rs73239714 | - | C>T | 121 | 101411 | 24.38 | 7.9e-07 | 1.624 |
| chr6:32546912 | rs34252386 | HLA-DRB1 | A>AG | 307 | 316081 | 24.23 | 8.54e-07 | 1.449 |
| chr1:146854836 | rs4950322 | - | G>A | 210 | 199541 | 24.15 | 8.918e-07 | 1.486 |
| chr6:32634838 | rs9274552 | HLA-DQB1 | C>A | 231 | 379109 | 23.53 | 1.231e-06 | 0.683 |
| chr8:144426181 | rs117390404 | TOP1MT | A>C | 71 | 52853 | 22.91 | 1.7e-06 | 1.803 |
| chr1:146881266 | rs58671552 | - | G>A | 208 | 198553 | 22.71 | 1.882e-06 | 1.471 |
| chr6:32626249 | rs6928482 | - | T>C | 421 | 425533 | 32.46 | 1.218e-08 | 1.521 |
| chr6:32657543 | rs4642516 | - | G>T | 427 | 436772 | 29.72 | 4.997e-08 | 1.495 |
| chr6:32546696 | rs3208409 | HLA-DRB1 | G>A | 327 | 319424 | 29.24 | 6.404e-08 | 1.489 |
| chr6:32637016 | rs9274697 | - | A>G | 426 | 437091 | 28.76 | 8.203e-08 | 1.486 |
| chr6:32546879 | Affx-28486470 | HLA-DRB1 | A>G | 328 | 320140 | 28.74 | 8.298e-08 | 1.483 |
| chr6:32546557 | rs34839759 | HLA-DRB1 | C>G | 327 | 318066 | 28.56 | 9.066e-08 | 1.482 |
| chr6:32560934 | rs28366302 | - | G>C | 328 | 320370 | 28.46 | 9.563e-08 | 1.48 |
| chr6:32434349 | rs9268969 | - | C>T | 333 | 327745 | 28.0 | 1.214e-07 | 1.475 |
| chr6:32492866 | rs111834747 | HLA-DRB5 | C>T | 321 | 313868 | 27.87 | 1.3e-07 | 1.48 |
| chr6:32550550 | rs28724008 | HLA-DRB1 | C>G | 332 | 325969 | 27.82 | 1.334e-07 | 1.473 |
| chr6:32433167 | rs2395185 | - | G>T | 329 | 323343 | 26.88 | 2.17e-07 | 1.465 |
| chr6:32432835 | rs9268923 | - | C>T | 331 | 327271 | 26.43 | 2.727e-07 | 1.459 |
| chr6:32429643 | rs9268853 | - | T>C | 330 | 326231 | 26.22 | 3.049e-07 | 1.459 |
| chr6:32546912 | rs34252386 | HLA-DRB1 | A>AG | 305 | 303711 | 24.42 | 7.735e-07 | 1.456 |
| chr6:32650612 | rs9275134 | - | C>G | 232 | 216785 | 24.27 | 8.39e-07 | 1.475 |
| chr16:81193358 | rs59878884 | - | C>G | 37 | 21159 | 23.71 | 1.122e-06 | 2.226 |
| chr6:32634838 | rs9274552 | HLA-DQB1 | C>A | 221 | 353326 | 23.44 | 1.289e-06 | 0.6788 |
| chr12:15130644 | rs10846103 | PDE6H | C>T | 38 | 22396 | 22.61 | 1.984e-06 | 2.167 |
| chr6:32635809 | rs3828790 | HLA-DQB1 | C>T | 220 | 350414 | 21.91 | 2.856e-06 | 0.6869 |
| chr6:32620775 | rs17843619 | - | A>C | 226 | 357926 | 21.77 | 3.07e-06 | 0.6901 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr6:32626249 | rs6928482 | - | T>C | 421 | 49149 | 31.44 | 2.061e-08 | 1.513 |
| chr6:32657543 | rs4642516 | - | G>T | 427 | 50466 | 28.64 | 8.718e-08 | 1.486 |
| chr6:32637016 | rs9274697 | - | A>G | 426 | 50536 | 27.55 | 1.53e-07 | 1.476 |
| chr6:32546696 | rs3208409 | HLA-DRB1 | G>A | 327 | 37054 | 27.36 | 1.686e-07 | 1.472 |
| chr6:32546879 | Affx-28486470 | HLA-DRB1 | A>G | 328 | 37164 | 26.84 | 2.208e-07 | 1.466 |
| chr6:32546557 | rs34839759 | HLA-DRB1 | C>G | 327 | 36897 | 26.81 | 2.249e-07 | 1.466 |
| chr6:32560934 | rs28366302 | - | G>C | 328 | 37170 | 26.62 | 2.482e-07 | 1.463 |
| chr6:32434349 | rs9268969 | - | C>T | 333 | 37988 | 26.37 | 2.813e-07 | 1.46 |
| chr6:32550550 | rs28724008 | HLA-DRB1 | C>G | 332 | 37780 | 26.25 | 3e-07 | 1.459 |
| chr6:32492866 | rs111834747 | HLA-DRB5 | C>T | 321 | 36392 | 26.15 | 3.166e-07 | 1.464 |
| chr6:32433167 | rs2395185 | - | G>T | 329 | 37439 | 25.42 | 4.617e-07 | 1.452 |
| chr6:32432835 | rs9268923 | - | C>T | 331 | 37966 | 24.73 | 6.59e-07 | 1.443 |
| chr6:32429643 | rs9268853 | - | T>C | 330 | 37835 | 24.65 | 6.873e-07 | 1.444 |
| chr6:32650612 | rs9275134 | - | C>G | 232 | 24990 | 23.91 | 1.009e-06 | 1.472 |
| chr16:81193358 | rs59878884 | - | C>G | 37 | 2451 | 23.04 | 1.586e-06 | 2.213 |
| chr6:32546912 | rs34252386 | HLA-DRB1 | A>AG | 305 | 35239 | 23.01 | 1.614e-06 | 1.442 |
| chr12:15130644 | rs10846103 | PDE6H | C>T | 38 | 2592 | 22.02 | 2.704e-06 | 2.156 |
| chr1:78064233 | rs116034016 | AC118549.1 | A>G | 25 | 1455 | 21.38 | 3.76e-06 | 2.5 |
| chr6:32634838 | rs9274552 | HLA-DQB1 | C>A | 221 | 40215 | 21.01 | 4.571e-06 | 0.692 |
| chr2:125143866 | rs80267316 | CNTNAP5 | C>T | 78 | 6754 | 20.82 | 5.057e-06 | 1.721 |
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: D071 | Vulva | 6/20 |
| ID | Name | Top Correlation |
|---|---|---|
| ICD-10: C519 | Vulva, unspecified | 0/20 |
| ICD-10: D280 | Vulva | 0/20 |