Statistics
| Case | Control |
|---|---|
| 3965 | 456229 |
Phenotype Definition
An abnormality of the conjuctiva and ocular surface caused by conjunctival inflammation and associated with scarring. [ORCID:0000-0003-0986-4123]
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr12:51138862 | rs1047912 | DIP2B | C>T | 2695 | 284420 | 31.73 | 1.768e-08 | 1.142 |
| chr12:51032415 | rs12818741 | DIP2B | A>G | 3194 | 341025 | 29.22 | 6.457e-08 | 1.13 |
| chr12:51213765 | rs11169571 | ATF1 | T>C | 3592 | 387291 | 28.21 | 1.088e-07 | 1.125 |
| chr12:51171090 | rs12372718 | ATF1 | A>G | 3584 | 386568 | 27.64 | 1.464e-07 | 1.124 |
| chr12:51203371 | rs1129406 | ATF1 | C>T | 3616 | 390970 | 27.39 | 1.659e-07 | 1.123 |
| chr20:6404281 | rs961253 | - | C>A | 3193 | 342357 | 27.39 | 1.663e-07 | 1.126 |
| chr18:46453463 | rs4939827 | SMAD7 | T>C | 3845 | 472258 | 25.83 | 3.738e-07 | 0.8939 |
| chr12:50707448 | rs35209607 | - | C>T | 3140 | 337503 | 25.55 | 4.307e-07 | 1.121 |
| chr12:50934931 | rs11169484 | DIP2B | G>A | 3157 | 339944 | 25.52 | 4.379e-07 | 1.121 |
| chr1:97968615 | rs2786782 | DPYD | G>A | 3065 | 379934 | 24.98 | 5.788e-07 | 0.8923 |
| chr12:50727706 | rs6580741 | FAM186A | G>C | 3148 | 338677 | 24.96 | 5.856e-07 | 1.12 |
| chr6:55708497 | rs2023523 | BMP5 | A>G | 3146 | 389687 | 24.41 | 7.799e-07 | 0.894 |
| chr12:50754563 | rs12303082 | FAM186A | G>T | 3166 | 340970 | 24.29 | 8.279e-07 | 1.118 |
| chr12:50610321 | rs12425705 | LIMA1 | T>C | 3125 | 337378 | 23.66 | 1.15e-06 | 1.117 |
| chr12:50744119 | rs7296291 | FAM186A | A>G | 3168 | 341683 | 23.61 | 1.179e-06 | 1.116 |
| chr6:55715715 | rs12215796 | BMP5 | G>A | 3624 | 444855 | 23.41 | 1.312e-06 | 0.8983 |
| chr8:62706102 | rs72660930 | - | G>T | 273 | 23695 | 23.07 | 1.562e-06 | 1.345 |
| chr19:46262286 | rs725660 | BHMG1 | C>A | 3218 | 347829 | 22.86 | 1.743e-06 | 1.114 |
| chr17:53735735 | rs8064405 | - | T>C | 808 | 109304 | 22.36 | 2.256e-06 | 0.8391 |
| chr5:40265904 | rs1348612 | - | A>G | 2529 | 270274 | 22.1 | 2.582e-06 | 1.119 |
| chr12:51138862 | rs1047912 | DIP2B | C>T | 2611 | 273513 | 32.93 | 9.551e-09 | 1.148 |
| chr12:51032415 | rs12818741 | DIP2B | A>G | 3049 | 322066 | 31.98 | 1.556e-08 | 1.14 |
| chr12:51213765 | rs11169571 | ATF1 | T>C | 3438 | 367342 | 30.63 | 3.128e-08 | 1.134 |
| chr12:51203371 | rs1129406 | ATF1 | C>T | 3440 | 368138 | 30.6 | 3.173e-08 | 1.134 |
| chr12:51171090 | rs12372718 | ATF1 | A>G | 3439 | 367701 | 29.87 | 4.609e-08 | 1.133 |
| chr12:50934931 | rs11169484 | DIP2B | G>A | 3014 | 321156 | 28.43 | 9.727e-08 | 1.132 |
| chr12:50707448 | rs35209607 | - | C>T | 2974 | 316342 | 27.96 | 1.238e-07 | 1.131 |
| chr12:50754563 | rs12303082 | FAM186A | G>T | 2976 | 316880 | 27.1 | 1.928e-07 | 1.129 |
| chr6:55715715 | rs12215796 | BMP5 | G>A | 3432 | 421920 | 27.06 | 1.968e-07 | 0.8882 |
| chr12:50727706 | rs6580741 | FAM186A | G>C | 2981 | 317481 | 26.99 | 2.04e-07 | 1.129 |
| chr12:50744119 | rs7296291 | FAM186A | A>G | 2980 | 317546 | 26.93 | 2.11e-07 | 1.128 |
| chr12:50610321 | rs12425705 | LIMA1 | T>C | 2943 | 314119 | 26.76 | 2.309e-07 | 1.129 |
| chr6:55708497 | rs2023523 | BMP5 | A>G | 2955 | 366058 | 26.25 | 2.995e-07 | 0.8873 |
| chr12:50723993 | rs7489214 | FAM186A | G>A | 3072 | 328687 | 25.36 | 4.76e-07 | 1.124 |
| chr1:97968615 | rs2786782 | DPYD | G>A | 2910 | 359199 | 24.35 | 8.049e-07 | 0.8909 |
| chr12:50570519 | rs9364 | LIMA1 | A>G | 3249 | 349425 | 24.02 | 9.558e-07 | 1.119 |
| chr18:46453463 | rs4939827 | SMAD7 | T>C | 3556 | 435122 | 24.01 | 9.6e-07 | 0.8946 |
| chr20:6404281 | rs961253 | - | C>A | 3040 | 325507 | 23.95 | 9.886e-07 | 1.12 |
| chr14:59183198 | rs17094971 | - | A>T | 702 | 95862 | 23.5 | 1.251e-06 | 0.8252 |
| chr1:10752990 | rs60449700 | CASZ1 | A>G | 387 | 34972 | 23.27 | 1.406e-06 | 1.287 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|
Associated Diseases ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| ICD: D122 | Ascending colon | 10/20 |
| ID | Name | Top Correlation |
|---|---|---|
| ICD-10: C182 | Ascending colon | 0/20 |
| ICD-10: H109 | Conjunctivitis, unspecified | 0/20 |