A49.1

Case	Control
139	460066

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds Ratio
chr10:127749020	rs75043911	ADAM12	G>A	14	12143	31.54	1.954e-08	4.132
chr13:96503660	rs72636544	UGGT2	C>T	16	15941	28.26	1.063e-07	3.595
chr9:74984701	rs117166269	-	T>C	13	11590	27.92	1.262e-07	4.005
chr9:75509710	rs78213778	-	C>T	12	10228	27.86	1.303e-07	4.189
chr8:21186155	rs79176487	-	G>C	13	11610	27.59	1.499e-07	3.975
chr17:15563361	rs73272121	TRIM16	A>G	12	10325	27.15	1.881e-07	4.123
chr9:75659371	rs78968062	ALDH1A1	G>A	12	10355	27.03	2.003e-07	4.111
chr7:1432565	rs117364498	-	G>A	18	19877	26.28	2.949e-07	3.253
chr14:72827427	rs77986082	RGS6	A>G	17	18233	26.26	2.977e-07	3.347
chr12:78876038	rs75990444	-	A>G	26	34101	26.07	3.287e-07	2.74
chr3:172155076	rs77178594	-	A>G	22	27358	25.74	3.91e-07	2.928
chr12:126004736	rs34013262	TMEM132B	C>T	25	33133	25.61	4.178e-07	2.763
chr4:144290735	rs79411017	GAB1	T>C	17	18694	24.82	6.278e-07	3.247
chr17:15546132	Affx-52330941	AC005324.3	T>TA	12	11176	23.68	1.137e-06	3.8
chr7:114014947	rs80298534	FOXP2	T>C	42	70993	23.65	1.156e-06	2.21
chr10:74809596	rs10458655	P4HA1	G>A	20	25258	22.92	1.688e-06	2.891
chr10:122504327	rs117240021	-	C>A	12	11428	22.81	1.788e-06	3.718
chr21:31622031	rs117971496	-	G>A	15	16201	22.76	1.833e-06	3.301
chr13:81241808	rs76723730	-	G>C	13	12945	22.68	1.909e-06	3.549
chr3:172140057	rs77839475	-	C>T	17	19673	22.52	2.081e-06	3.086
chr17:15546132	Affx-52330941	AC005324.3	T>TA	10	7186	28.34	1.019e-07	4.732
chr17:15563361	rs73272121	TRIM16	A>G	10	7224	28.14	1.131e-07	4.71
chr9:74984701	rs117166269	-	T>C	13	11239	27.62	1.477e-07	3.982
chr9:75509710	rs78213778	-	C>T	12	9922	27.53	1.546e-07	4.161
chr13:96503660	rs72636544	UGGT2	C>T	16	15671	27.22	1.815e-07	3.523
chr9:75659371	rs78968062	ALDH1A1	G>A	12	10023	26.8	2.258e-07	4.092
chr7:1432565	rs117364498	-	G>A	18	19454	25.47	4.484e-07	3.202
chr10:127749020	rs75043911	ADAM12	G>A	13	11812	25.38	4.72e-07	3.787
chr3:172155076	rs77178594	-	A>G	22	26846	24.75	6.538e-07	2.875
chr12:78876038	rs75990444	-	A>G	25	31975	24.36	7.981e-07	2.701
chr4:144290735	rs79411017	GAB1	T>C	17	18192	24.33	8.13e-07	3.215
chr25:641362	rs191805812	-	T>C	13	11944	24.24	8.527e-07	3.687
chr7:114014947	rs80298534	FOXP2	T>C	41	65980	23.86	1.037e-06	2.238
chr1:14963447	rs77048522	KAZN	A>G	16	16818	23.78	1.077e-06	3.273
chr8:21186155	rs79176487	-	G>C	12	10947	22.99	1.631e-06	3.737
chr12:126004736	rs34013262	TMEM132B	C>T	24	31955	22.33	2.293e-06	2.641
chr21:31622031	rs117971496	-	G>A	15	15923	21.89	2.884e-06	3.235
chr10:122504327	rs117240021	-	C>A	12	11278	21.84	2.961e-06	3.629
chr13:81241808	rs76723730	-	G>C	13	12760	21.74	3.124e-06	3.468
chr3:172140057	rs77839475	-	C>T	17	19353	21.57	3.407e-06	3.022
chr17:15546132	Affx-52330941	AC005324.3	T>TA	10	7186	28.34	1.019e-07	4.732
chr17:15563361	rs73272121	TRIM16	A>G	10	7224	28.14	1.131e-07	4.71
chr9:74984701	rs117166269	-	T>C	13	11239	27.62	1.477e-07	3.982
chr9:75509710	rs78213778	-	C>T	12	9922	27.53	1.546e-07	4.161
chr13:96503660	rs72636544	UGGT2	C>T	16	15671	27.22	1.815e-07	3.523
chr9:75659371	rs78968062	ALDH1A1	G>A	12	10023	26.8	2.258e-07	4.092
chr7:1432565	rs117364498	-	G>A	18	19454	25.47	4.484e-07	3.202
chr10:127749020	rs75043911	ADAM12	G>A	13	11812	25.38	4.72e-07	3.787
chr3:172155076	rs77178594	-	A>G	22	26846	24.75	6.538e-07	2.875
chr12:78876038	rs75990444	-	A>G	25	31975	24.36	7.981e-07	2.701
chr4:144290735	rs79411017	GAB1	T>C	17	18192	24.33	8.13e-07	3.215
chr25:641362	rs191805812	-	T>C	13	11944	24.24	8.527e-07	3.687
chr7:114014947	rs80298534	FOXP2	T>C	41	65980	23.86	1.037e-06	2.238
chr1:14963447	rs77048522	KAZN	A>G	16	16818	23.78	1.077e-06	3.273
chr8:21186155	rs79176487	-	G>C	12	10947	22.99	1.631e-06	3.737
chr12:126004736	rs34013262	TMEM132B	C>T	24	31955	22.33	2.293e-06	2.641
chr21:31622031	rs117971496	-	G>A	15	15923	21.89	2.884e-06	3.235
chr10:122504327	rs117240021	-	C>A	12	11278	21.84	2.961e-06	3.629
chr13:81241808	rs76723730	-	G>C	13	12760	21.74	3.124e-06	3.468
chr3:172140057	rs77839475	-	C>T	17	19353	21.57	3.407e-06	3.022

Location

SNP

Gene

Ref>Alt

Alt in Case

Alt in Control

Chi-square

P-value

Odds Ratio

chr10:127749020

rs75043911

ADAM12

G>A

14

12143

31.54

1.954e-08

4.132

chr13:96503660

rs72636544

UGGT2

C>T

16

15941

28.26

1.063e-07

3.595

chr9:74984701

rs117166269

-

T>C

13

11590

27.92

1.262e-07

4.005

chr9:75509710

rs78213778

-

C>T

12

10228

27.86

1.303e-07

4.189

chr8:21186155

rs79176487

-

G>C

13

11610

27.59

1.499e-07

3.975

chr17:15563361

rs73272121

TRIM16

A>G

12

10325

27.15

1.881e-07

4.123

chr9:75659371

rs78968062

ALDH1A1

G>A

12

10355

27.03

2.003e-07

4.111

chr7:1432565

rs117364498

-

G>A

18

19877

26.28

2.949e-07

3.253

chr14:72827427

rs77986082

RGS6

A>G

17

18233

26.26

2.977e-07

3.347

chr12:78876038

rs75990444

-

A>G

26

34101

26.07

3.287e-07

2.74

chr3:172155076

rs77178594

-

A>G

22

27358

25.74

3.91e-07

2.928

chr12:126004736

rs34013262

TMEM132B

C>T

25

33133

25.61

4.178e-07

2.763

chr4:144290735

rs79411017

GAB1

T>C

17

18694

24.82

6.278e-07

3.247

chr17:15546132

Affx-52330941

AC005324.3

T>TA

12

11176

23.68

1.137e-06

3.8

chr7:114014947

rs80298534

FOXP2

T>C

42

70993

23.65

1.156e-06

2.21

chr10:74809596

rs10458655

P4HA1

G>A

20

25258

22.92

1.688e-06

2.891

chr10:122504327

rs117240021

-

C>A

12

11428

22.81

1.788e-06

3.718

chr21:31622031

rs117971496

-

G>A

15

16201

22.76

1.833e-06

3.301

chr13:81241808

rs76723730

-

G>C

13

12945

22.68

1.909e-06

3.549

chr3:172140057

rs77839475

-

C>T

17

19673

22.52

2.081e-06

3.086

chr17:15546132

Affx-52330941

AC005324.3

T>TA

10

7186

28.34

1.019e-07

4.732

chr17:15563361

rs73272121

TRIM16

A>G

10

7224

28.14

1.131e-07

4.71

chr9:74984701

rs117166269

-

T>C

13

11239

27.62

1.477e-07

3.982

chr9:75509710

rs78213778

-

C>T

12

9922

27.53

1.546e-07

4.161

chr13:96503660

rs72636544

UGGT2

C>T

16

15671

27.22

1.815e-07

3.523

chr9:75659371

rs78968062

ALDH1A1

G>A

12

10023

26.8

2.258e-07

4.092

chr7:1432565

rs117364498

-

G>A

18

19454

25.47

4.484e-07

3.202

chr10:127749020

rs75043911

ADAM12

G>A

13

11812

25.38

4.72e-07

3.787

chr3:172155076

rs77178594

-

A>G

22

26846

24.75

6.538e-07

2.875

chr12:78876038

rs75990444

-

A>G

25

31975

24.36

7.981e-07

2.701

chr4:144290735

rs79411017

GAB1

T>C

17

18192

24.33

8.13e-07

3.215

chr25:641362

rs191805812

-

T>C

13

11944

24.24

8.527e-07

3.687

chr7:114014947

rs80298534

FOXP2

T>C

41

65980

23.86

1.037e-06

2.238

chr1:14963447

rs77048522

KAZN

A>G

16

16818

23.78

1.077e-06

3.273

chr8:21186155

rs79176487

-

G>C

12

10947

22.99

1.631e-06

3.737

chr12:126004736

rs34013262

TMEM132B

C>T

24

31955

22.33

2.293e-06

2.641

chr21:31622031

rs117971496

-

G>A

15

15923

21.89

2.884e-06

3.235

chr10:122504327

rs117240021

-

C>A

12

11278

21.84

2.961e-06

3.629

chr13:81241808

rs76723730

-

G>C

13

12760

21.74

3.124e-06

3.468

chr3:172140057

rs77839475

-

C>T

17

19353

21.57

3.407e-06

3.022

chr17:15546132

Affx-52330941

AC005324.3

T>TA

10

7186

28.34

1.019e-07

4.732

chr17:15563361

rs73272121

TRIM16

A>G

10

7224

28.14

1.131e-07

4.71

chr9:74984701

rs117166269

-

T>C

13

11239

27.62

1.477e-07

3.982

chr9:75509710

rs78213778

-

C>T

12

9922

27.53

1.546e-07

4.161

chr13:96503660

rs72636544

UGGT2

C>T

16

15671

27.22

1.815e-07

3.523

chr9:75659371

rs78968062

ALDH1A1

G>A

12

10023

26.8

2.258e-07

4.092

chr7:1432565

rs117364498

-

G>A

18

19454

25.47

4.484e-07

3.202

chr10:127749020

rs75043911

ADAM12

G>A

13

11812

25.38

4.72e-07

3.787

chr3:172155076

rs77178594

-

A>G

22

26846

24.75

6.538e-07

2.875

chr12:78876038

rs75990444

-

A>G

25

31975

24.36

7.981e-07

2.701

chr4:144290735

rs79411017

GAB1

T>C

17

18192

24.33

8.13e-07

3.215

chr25:641362

rs191805812

-

T>C

13

11944

24.24

8.527e-07

3.687

chr7:114014947

rs80298534

FOXP2

T>C

41

65980

23.86

1.037e-06

2.238

chr1:14963447

rs77048522

KAZN

A>G

16

16818

23.78

1.077e-06

3.273

chr8:21186155

rs79176487

-

G>C

12

10947

22.99

1.631e-06

3.737

chr12:126004736

rs34013262

TMEM132B

C>T

24

31955

22.33

2.293e-06

2.641

chr21:31622031

rs117971496

-

G>A

15

15923

21.89

2.884e-06

3.235

chr10:122504327

rs117240021

-

C>A

12

11278

21.84

2.961e-06

3.629

chr13:81241808

rs76723730

-

G>C

13

12760

21.74

3.124e-06

3.468

chr3:172140057

rs77839475

-

C>T

17

19353

21.57

3.407e-06

3.022

ID	Name	Top Correlation
HP: 0000118	Phenotypic abnormality	0/20
HP: 0000152	Abnormality of head or neck	0/20
HP: 0000234	Abnormality of the head	0/20
HP: 0000271	Abnormality of the face	0/20
HP: 0000366	Abnormality of the nose	0/20
HP: 0000478	Abnormality of the eye	0/20
HP: 0000553	Abnormal uvea morphology	0/20
HP: 0000554	Uveitis	0/20
HP: 0000600	Abnormality of the pharynx	0/20
HP: 0000707	Abnormality of the nervous system	0/20
HP: 0000708	Behavioral abnormality	0/20
HP: 0000924	Abnormality of the skeletal system	0/20
HP: 0001197	Abnormality of prenatal development or birth	0/20
HP: 0001367	Abnormal joint morphology	0/20
HP: 0001369	Arthritis	0/20
HP: 0001626	Abnormality of the cardiovascular system	0/20
HP: 0001739	Abnormality of the nasopharynx	0/20
HP: 0001939	Abnormality of metabolism/homeostasis	0/20
HP: 0001945	Fever	0/20
HP: 0002072	Chorea	0/20
HP: 0002086	Abnormality of the respiratory system	0/20
HP: 0002088	Abnormal lung morphology	0/20
HP: 0002205	Recurrent respiratory infections	0/20
HP: 0002597	Abnormality of the vasculature	0/20
HP: 0002686	Prenatal maternal abnormality	0/20
HP: 0002715	Abnormality of the immune system	0/20
HP: 0002718	Recurrent bacterial infections	0/20
HP: 0002719	Recurrent infections	0/20
HP: 0002788	Recurrent upper respiratory tract infections	0/20
HP: 0003549	Abnormality of connective tissue	0/20
HP: 0004305	Involuntary movements	0/20
HP: 0004370	Abnormality of temperature regulation	0/20
HP: 0010978	Abnormality of immune system physiology	0/20
HP: 0011110	Tonsillitis	0/20
HP: 0011842	Abnormality of skeletal morphology	0/20
HP: 0011947	Respiratory tract infection	0/20
HP: 0012252	Abnormal respiratory system morphology	0/20
HP: 0012337	Abnormal homeostasis	0/20
HP: 0012372	Abnormal eye morphology	0/20
HP: 0012373	Abnormal eye physiology	0/20
HP: 0012638	Abnormal nervous system physiology	0/20
HP: 0012647	Abnormal inflammatory response	0/20
HP: 0012649	Increased inflammatory response	0/20
HP: 0020096	Recurrent streptococcal infections	0/20
HP: 0025031	Abnormality of the digestive system	0/20
HP: 0025439	Pharyngitis	0/20
HP: 0030244	Maternal fever in pregnancy	0/20
HP: 0030245	Intrapartum fever	0/20
HP: 0032101	Unusual infection	0/20
HP: 0040310	Sterile arthritis	0/20
HP: 0100022	Abnormality of movement	0/20
HP: 0100033	Tics	0/20
HP: 0100533	Inflammatory abnormality of the eye	0/20
HP: 0100536	Abnormality of the fascia	0/20
HP: 0100537	Fasciitis	0/20
HP: 0100763	Abnormality of the lymphatic system	0/20
HP: 0100765	Abnormality of the tonsils	0/20
HP: 0100776	Recurrent pharyngitis	0/20

Streptococcal infection, unspecified

A49.1

Case/Control GWAS ^ⓘ

Links

Statistics

Top SNP Information

Associated Phenotypes ^ⓘ

Streptococcal infection, unspecified

A49.1

Case/Control GWAS ⓘ

Links

Statistics

Top SNP Information Show Table

Associated Phenotypes ⓘ Shared SNP phenotypes No shared SNP phenotypes

Case/Control GWAS ^ⓘ

Top SNP Information

Associated Phenotypes ^ⓘ