Mental and behavioural disorders

Chapter5

Case/Control GWAS

GWAS of Chapter5

Statistics

Case Control
45876 414330

Top SNP Information

Associated Phenotypes

ID Name Top Correlation
HP: 0000009 Functional abnormality of the bladder 2/20
HP: 0000014 Abnormality of the bladder 2/20
HP: 0000032 Abnormality of male external genitalia 4/20
HP: 0000037 Male pseudohermaphroditism 3/20
HP: 0000055 Abnormality of female external genitalia 1/20
HP: 0000077 Abnormality of the kidney 1/20
HP: 0000118 Phenotypic abnormality 4/20
HP: 0000152 Abnormality of head or neck 5/20
HP: 0000153 Abnormality of the mouth 6/20
HP: 0000159 Abnormal lip morphology 2/20
HP: 0000163 Abnormal oral cavity morphology 6/20
HP: 0000168 Abnormality of the gingiva 1/20
HP: 0000172 Abnormality of the uvula 2/20
HP: 0000234 Abnormality of the head 5/20
HP: 0000240 Abnormality of skull size 2/20
HP: 0000252 Microcephaly 2/20
HP: 0000271 Abnormality of the face 6/20
HP: 0000282 Facial edema 2/20
HP: 0000315 Abnormality of the orbital region 1/20
HP: 0000359 Abnormality of the inner ear 1/20
HP: 0000366 Abnormality of the nose 1/20
HP: 0000478 Abnormality of the eye 2/20
HP: 0000479 Abnormal retinal morphology 1/20
HP: 0000486 Strabismus 3/20
HP: 0000492 Abnormal eyelid morphology 3/20
HP: 0000496 Abnormality of eye movement 3/20
HP: 0000504 Abnormality of vision 1/20
HP: 0000505 Visual impairment 1/20
HP: 0000549 Abnormal conjugate eye movement 3/20
HP: 0000570 Abnormal saccadic eye movements 3/20
HP: 0000598 Abnormality of the ear 1/20
HP: 0000606 Abnormality of the periorbital region 2/20
HP: 0000617 Abnormality of ocular smooth pursuit 3/20
HP: 0000639 Nystagmus 1/20
HP: 0000640 Gaze-evoked nystagmus 4/20
HP: 0000704 Periodontitis 2/20
HP: 0000707 Abnormality of the nervous system 2/20
HP: 0000708 Behavioral abnormality 3/20
HP: 0000709 Psychosis 7/20
HP: 0000713 Agitation 1/20
HP: 0000716 Depressivity 1/20
HP: 0000719 Inappropriate behavior 2/20
HP: 0000720 Mood swings 6/20
HP: 0000725 Psychotic episodes 6/20
HP: 0000729 Autistic behavior 2/20
HP: 0000735 Impaired social interactions 2/20
HP: 0000736 Short attention span 4/20
HP: 0000737 Irritability 2/20
HP: 0000739 Anxiety 3/20
HP: 0000742 Self-mutilation 3/20
HP: 0000752 Hyperactivity 4/20
HP: 0000756 Agoraphobia 7/20
HP: 0000763 Sensory neuropathy 1/20
HP: 0000765 Abnormality of the thorax 2/20
HP: 0000811 Abnormal external genitalia 6/20
HP: 0000828 Abnormality of the parathyroid gland 2/20
HP: 0000864 Abnormality of the hypothalamus-pituitary axis 3/20
HP: 0000924 Abnormality of the skeletal system 4/20
HP: 0000925 Abnormality of the vertebral column 3/20
HP: 0000929 Abnormal skull morphology 6/20
HP: 0000951 Abnormality of the skin 4/20
HP: 0000952 Jaundice 2/20
HP: 0000961 Cyanosis 1/20
HP: 0000969 Edema 1/20
HP: 0001063 Acrocyanosis 1/20
HP: 0001103 Abnormal macular morphology 1/20
HP: 0001133 Constriction of peripheral visual field 1/20
HP: 0001152 Saccadic smooth pursuit 3/20
HP: 0001155 Abnormality of the hand 2/20
HP: 0001197 Abnormality of prenatal development or birth 1/20
HP: 0001249 Intellectual disability 7/20
HP: 0001287 Meningitis 2/20
HP: 0001288 Gait disturbance 2/20
HP: 0001289 Confusion 2/20
HP: 0001291 Abnormal cranial nerve morphology 1/20
HP: 0001297 Stroke 1/20
HP: 0001300 Parkinsonism 1/20
HP: 0001311 Abnormal nervous system electrophysiology 3/20
HP: 0001337 Tremor 2/20
HP: 0001357 Plagiocephaly 5/20
HP: 0001367 Abnormal joint morphology 4/20
HP: 0001371 Flexion contracture 2/20
HP: 0001560 Abnormality of the amniotic fluid 1/20
HP: 0001574 Abnormality of the integument 4/20
HP: 0001595 Abnormal hair morphology 3/20
HP: 0001596 Alopecia 1/20
HP: 0001626 Abnormality of the cardiovascular system 5/20
HP: 0001751 Vestibular dysfunction 1/20
HP: 0001787 Abnormal delivery 2/20
HP: 0001871 Abnormality of blood and blood-forming tissues 2/20
HP: 0001872 Abnormal thrombocyte morphology 1/20
HP: 0001874 Abnormality of neutrophils 1/20
HP: 0001881 Abnormal leukocyte morphology 3/20
HP: 0001911 Abnormal granulocyte morphology 1/20
HP: 0001941 Acidosis 1/20
HP: 0001943 Hypoglycemia 1/20
HP: 0001952 Glucose intolerance 2/20
HP: 0001962 Palpitations 2/20
HP: 0001999 Abnormal facial shape 2/20
HP: 0002011 Morphological central nervous system abnormality 4/20
HP: 0002012 Abnormality of the abdominal organs 1/20
HP: 0002019 Constipation 1/20
HP: 0002034 Abnormality of the rectum 2/20
HP: 0002037 Inflammation of the large intestine 2/20
HP: 0002047 Malignant hyperthermia 3/20
HP: 0002060 Abnormal cerebral morphology 4/20
HP: 0002069 Bilateral tonic-clonic seizure 2/20
HP: 0002071 Abnormality of extrapyramidal motor function 2/20
HP: 0002076 Migraine 2/20
HP: 0002086 Abnormality of the respiratory system 4/20
HP: 0002087 Abnormality of the upper respiratory tract 6/20
HP: 0002143 Abnormality of the spinal cord 3/20
HP: 0002197 Generalized-onset seizure 2/20
HP: 0002242 Abnormal intestine morphology 3/20
HP: 0002250 Abnormal large intestine morphology 3/20
HP: 0002311 Incoordination 2/20
HP: 0002315 Headache 2/20
HP: 0002342 Intellectual disability, moderate 5/20
HP: 0002353 EEG abnormality 2/20
HP: 0002354 Memory impairment 2/20
HP: 0002360 Sleep disturbance 2/20
HP: 0002367 Visual hallucinations 2/20
HP: 0002376 Developmental regression 1/20
HP: 0002474 Expressive language delay 1/20
HP: 0002493 Upper motor neuron dysfunction 1/20
HP: 0002519 Hypnagogic hallucinations 1/20
HP: 0002538 Abnormality of the cerebral cortex 1/20
HP: 0002577 Abnormality of the stomach 1/20
HP: 0002583 Colitis 2/20
HP: 0002597 Abnormality of the vasculature 5/20
HP: 0002644 Abnormality of pelvic girdle bone morphology 2/20
HP: 0002648 Abnormality of calvarial morphology 6/20
HP: 0002664 Neoplasm 4/20
HP: 0002672 Gastrointestinal carcinoma 2/20
HP: 0002683 Abnormality of the calvaria 6/20
HP: 0002686 Prenatal maternal abnormality 2/20
HP: 0002715 Abnormality of the immune system 2/20
HP: 0002719 Recurrent infections 1/20
HP: 0002778 Abnormal trachea morphology 2/20
HP: 0002813 Abnormality of limb bone morphology 3/20
HP: 0002814 Abnormality of the lower limb 3/20
HP: 0002815 Abnormality of the knee 4/20
HP: 0002817 Abnormality of the upper limb 3/20
HP: 0002870 Obstructive sleep apnea 1/20
HP: 0002883 Hyperventilation 2/20
HP: 0002973 Abnormality of the forearm 2/20
HP: 0003003 Colon cancer 2/20
HP: 0003011 Abnormality of the musculature 6/20
HP: 0003026 Short long bone 2/20
HP: 0003077 Hyperlipidemia 2/20
HP: 0003107 Abnormal circulating cholesterol concentration 2/20
HP: 0003110 Abnormality of urine homeostasis 2/20
HP: 0003115 Abnormal EKG 2/20
HP: 0003119 Abnormal circulating lipid concentration 1/20
HP: 0003121 Limb joint contracture 2/20
HP: 0003128 Lactic acidosis 2/20
HP: 0003272 Abnormality of the hip bone 2/20
HP: 0003549 Abnormality of connective tissue 2/20
HP: 0004298 Abnormality of the abdominal wall 2/20
HP: 0004328 Abnormal anterior eye segment morphology 2/20
HP: 0004340 Abnormality of vitamin B metabolism 2/20
HP: 0004341 Abnormality of vitamin B12 metabolism 2/20
HP: 0004364 Abnormal circulating nitrogen compound concentration 1/20
HP: 0004370 Abnormality of temperature regulation 2/20
HP: 0004372 Reduced consciousness/confusion 2/20
HP: 0004375 Neoplasm of the nervous system 1/20
HP: 0004386 Gastrointestinal inflammation 1/20
HP: 0004389 Intestinal pseudo-obstruction 2/20
HP: 0004437 Cranial hyperostosis 2/20
HP: 0004438 Hyperostosis frontalis interna 2/20
HP: 0004879 Intermittent hyperventilation 2/20
HP: 0004900 Severe lactic acidosis 4/20
HP: 0005105 Abnormal nasal morphology 2/20
HP: 0005268 Spontaneous abortion 2/20
HP: 0005607 Abnormal tracheobronchial morphology 4/20
HP: 0005750 Contractures of the joints of the lower limbs 2/20
HP: 0006380 Knee flexion contracture 2/20
HP: 0006707 Abnormality of the hepatic vasculature 2/20
HP: 0006749 Malignant gastrointestinal tract tumors 2/20
HP: 0006803 Vivid hallucinations 1/20
HP: 0006919 Abnormal aggressive, impulsive or violent behavior 10/20
HP: 0006979 Sleep-wake cycle disturbance 2/20
HP: 0007018 Attention deficit hyperactivity disorder 4/20
HP: 0007302 Bipolar affective disorder 8/20
HP: 0007359 Focal-onset seizure 1/20
HP: 0007364 Aplasia/Hypoplasia of the cerebrum 2/20
HP: 0007378 Neoplasm of the gastrointestinal tract 2/20
HP: 0007670 Abnormal vestibulo-ocular reflex 1/20
HP: 0009115 Aplasia/hypoplasia involving the skeleton 6/20
HP: 0009121 Abnormal axial skeleton morphology 4/20
HP: 0009127 Abnormality of the musculature of the limbs 1/20
HP: 0009800 Maternal diabetes 2/20
HP: 0009815 Aplasia/hypoplasia of the extremities 4/20
HP: 0009824 Upper limb undergrowth 2/20
HP: 0010461 Abnormality of the male genitalia 4/20
HP: 0010865 Oppositional defiant disorder 2/20
HP: 0010866 Abdominal wall defect 2/20
HP: 0010935 Abnormality of the upper urinary tract 1/20
HP: 0010936 Abnormality of the lower urinary tract 2/20
HP: 0010939 Abnormality of the nasal bone 2/20
HP: 0010978 Abnormality of immune system physiology 1/20
HP: 0010979 Abnormality of lipoprotein cholesterol concentration 2/20
HP: 0010980 Hyperlipoproteinemia 2/20
HP: 0010987 Abnormal cellular immune system morphology 3/20
HP: 0011014 Abnormal glucose homeostasis 2/20
HP: 0011015 Abnormal blood glucose concentration 2/20
HP: 0011024 Abnormality of the gastrointestinal tract 1/20
HP: 0011025 Abnormal cardiovascular system physiology 4/20
HP: 0011032 Abnormality of fluid regulation 1/20
HP: 0011058 Generalized periodontitis 2/20
HP: 0011121 Abnormality of skin morphology 3/20
HP: 0011122 Abnormality of skin physiology 3/20
HP: 0011124 Abnormality of epidermal morphology 1/20
HP: 0011138 Abnormality of skin adnexa morphology 3/20
HP: 0011157 Focal sensory seizure 2/20
HP: 0011276 Vascular skin abnormality 3/20
HP: 0011297 Abnormal digit morphology 2/20
HP: 0011314 Abnormality of long bone morphology 6/20
HP: 0011338 Abnormality of mouth shape 2/20
HP: 0011354 Generalized abnormality of skin 2/20
HP: 0011362 Abnormal hair quantity 1/20
HP: 0011368 Epidermal thickening 1/20
HP: 0011389 Functional abnormality of the inner ear 1/20
HP: 0011440 Alcohol-induced rhabdomyolysis 4/20
HP: 0011442 Abnormal central motor function 2/20
HP: 0011446 Abnormality of higher mental function 4/20
HP: 0011458 Abdominal symptom 1/20
HP: 0011729 Abnormality of joint mobility 2/20
HP: 0011747 Abnormality of the anterior pituitary 3/20
HP: 0011792 Neoplasm by histology 1/20
HP: 0011793 Neoplasm by anatomical site 4/20
HP: 0011799 Abnormality of facial soft tissue 3/20
HP: 0011805 Abnormal skeletal muscle morphology 4/20
HP: 0011821 Abnormality of facial skeleton 1/20
HP: 0011830 Abnormal oral mucosa morphology 2/20
HP: 0011842 Abnormality of skeletal morphology 4/20
HP: 0011843 Abnormality of skeletal physiology 4/20
HP: 0011844 Abnormal appendicular skeleton morphology 4/20
HP: 0011893 Abnormal leukocyte count 3/20
HP: 0011991 Abnormal neutrophil count 1/20
HP: 0012075 Personality disorder 1/20
HP: 0012076 Borderline personality disorder 2/20
HP: 0012154 Anhedonia 4/20
HP: 0012166 Skin-picking 8/20
HP: 0012167 Hair-pulling 5/20
HP: 0012210 Abnormal renal morphology 2/20
HP: 0012252 Abnormal respiratory system morphology 4/20
HP: 0012337 Abnormal homeostasis 2/20
HP: 0012372 Abnormal eye morphology 1/20
HP: 0012373 Abnormal eye physiology 2/20
HP: 0012433 Abnormal social behavior 2/20
HP: 0012443 Abnormality of brain morphology 4/20
HP: 0012452 Restless legs 2/20
HP: 0012503 Abnormality of the pituitary gland 3/20
HP: 0012531 Pain 2/20
HP: 0012547 Abnormal involuntary eye movements 1/20
HP: 0012638 Abnormal nervous system physiology 3/20
HP: 0012639 Abnormal nervous system morphology 4/20
HP: 0012647 Abnormal inflammatory response 1/20
HP: 0012649 Increased inflammatory response 1/20
HP: 0012718 Morphological abnormality of the gastrointestinal tract 1/20
HP: 0012719 Functional abnormality of the gastrointestinal tract 1/20
HP: 0012732 Anorectal anomaly 3/20
HP: 0012759 Neurodevelopmental abnormality 7/20
HP: 0025015 Abnormal vascular morphology 1/20
HP: 0025031 Abnormality of the digestive system 3/20
HP: 0025032 Abnormality of digestive system physiology 1/20
HP: 0025033 Abnormality of digestive system morphology 3/20
HP: 0025142 Constitutional symptom 2/20
HP: 0025233 Sleep paralysis 2/20
HP: 0025253 Claustrophobia 6/20
HP: 0025267 Snoring 2/20
HP: 0025269 Panic attack 4/20
HP: 0025356 Psychomotor retardation 4/20
HP: 0025373 Interictal EEG abnormality 2/20
HP: 0030016 Dyspareunia 1/20
HP: 0030163 Abnormal vascular physiology 2/20
HP: 0030178 Abnormality of central nervous system electrophysiology 2/20
HP: 0030218 Punding 2/20
HP: 0030220 Socially inappropriate behavior 4/20
HP: 0030516 Homonymous hemianopia 2/20
HP: 0030669 Abnormal ocular adnexa morphology 1/20
HP: 0030680 Abnormality of cardiovascular system morphology 4/20
HP: 0030858 Addictive behavior 2/20
HP: 0030917 Low APGAR score 1/20
HP: 0030955 Alcoholism 2/20
HP: 0030956 Abnormality of cardiovascular system electrophysiology 1/20
HP: 0031015 Intrahepatic portal vein sclerosis 2/20
HP: 0031058 Impairment of activities of daily living 3/20
HP: 0031064 Impaired continence 3/20
HP: 0031258 Delirium 2/20
HP: 0031273 Shock 3/20
HP: 0031275 Distributive shock 4/20
HP: 0031356 Terminal insomnia 4/20
HP: 0031466 Impairment in personality functioning 12/20
HP: 0031469 Low self esteem 1/20
HP: 0031589 Suicidal ideation 4/20
HP: 0031704 Abnormal ear physiology 1/20
HP: 0031816 Abnormal oral morphology 6/20
HP: 0031879 Abnormal eyelid physiology 1/20
HP: 0031941 Abnormal portal venous system morphology 2/20
HP: 0031951 Nocturnal seizures 5/20
HP: 0031953 Cautious gait 2/20
HP: 0032012 Heterotropia 3/20
HP: 0032039 Abnormality of the ocular adnexa 1/20
HP: 0032040 Abnormal ocular adnexa physiology 1/20
HP: 0032101 Unusual infection 1/20
HP: 0032141 Precordial pain 1/20
HP: 0032154 Aphthous ulcer 7/20
HP: 0032158 Unusual infection by anatomical site 1/20
HP: 0032180 Abnormal circulating metabolite concentration 1/20
HP: 0032245 Abnormal metabolism 2/20
HP: 0032251 Abnormal immune system morphology 5/20
HP: 0032309 Abnormal granulocyte count 1/20
HP: 0040064 Abnormality of limbs 3/20
HP: 0040068 Abnormality of limb bone 3/20
HP: 0040069 Abnormal lower limb bone morphology 2/20
HP: 0040070 Abnormal upper limb bone morphology 6/20
HP: 0040194 Increased head circumference 2/20
HP: 0040195 Decreased head circumference 2/20
HP: 0045060 Aplasia/hypoplasia involving bones of the extremities 4/20
HP: 0100006 Neoplasm of the central nervous system 1/20
HP: 0100008 Schwannoma 1/20
HP: 0100022 Abnormality of movement 6/20
HP: 0100261 Abnormal tendon morphology 1/20
HP: 0100273 Neoplasm of the colon 2/20
HP: 0100279 Ulcerative colitis 2/20
HP: 0100280 Crohn's disease 2/20
HP: 0100281 Chronic colitis 2/20
HP: 0100314 Cerebral inclusion bodies 2/20
HP: 0100315 Lewy bodies 2/20
HP: 0100491 Abnormality of lower limb joint 2/20
HP: 0100508 Abnormality of vitamin metabolism 2/20
HP: 0100539 Periorbital edema 2/20
HP: 0100543 Cognitive impairment 2/20
HP: 0100547 Abnormality of forebrain morphology 4/20
HP: 0100548 Exstrophy 2/20
HP: 0100555 Asymmetric growth 3/20
HP: 0100705 Abnormality of the glial cells 1/20
HP: 0100716 Self-injurious behavior 9/20
HP: 0100749 Chest pain 2/20
HP: 0100754 Mania 8/20
HP: 0100767 Abnormality of the placenta 1/20
HP: 0100774 Hyperostosis 2/20
HP: 0100785 Insomnia 2/20
HP: 0100786 Hypersomnia 4/20
HP: 0100790 Hernia 2/20
HP: 0100825 Cheilitis 3/20
HP: 0100834 Neoplasm of the large intestine 2/20
HP: 0100851 Abnormal emotion/affect behavior 7/20
HP: 0100852 Abnormal fear/anxiety-related behavior 14/20
HP: 0430000 Abnormality of the frontal bone 2/20
HP: 0500015 Abnormal cardiac test 2/20