F06

Case	Control
415	459779

Case

Control

415

459779

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds Ratio
chr9:13361797	rs1147784	-	A>C	29	12468	27.79	1.349e-07	2.61
chr3:2479868	rs114170996	CNTN4	G>A	44	22594	27.37	1.682e-07	2.202
chr6:32282216	rs6931409	TSBP1	T>G	26	11401	23.95	9.879e-07	2.561
chr6:32268429	rs11969268	TSBP1	G>C	26	11386	23.91	1.011e-06	2.559
chr13:53900807	rs117778902	-	G>A	28	12654	23.87	1.029e-06	2.479
chr19:45410002	rs769449	APOE	G>A	154	117767	23.37	1.338e-06	1.531
chr12:75257481	rs144765310	-	C>T	24	10323	22.98	1.634e-06	2.602
chr6:32264645	rs11970194	TSBP1	C>T	32	15700	22.38	2.234e-06	2.291
chr6:32261014	rs7751028	TSBP1	C>A	32	15892	21.76	3.097e-06	2.265
chr2:149148673	rs74878285	MBD5	A>G	48	27698	21.41	3.701e-06	1.963
chr8:47325114	rs2133027	-	G>A	28	13371	20.81	5.082e-06	2.342
chr3:29320253	rs11709388	AC098650.1	A>G	206	170587	20.48	6.023e-06	1.431
chr9:138220060	rs10858388	-	A>G	407	375765	20.09	7.374e-06	1.351
chr2:219000460	rs45606837	CXCR2	C>T	24	11021	19.68	9.141e-06	2.434
chr6:42436170	rs12374629	-	G>A	44	25325	19.63	9.417e-06	1.96
chr6:31470455	rs116226697	MICB	T>C	40	22279	19.44	1.039e-05	2.013
chr10:134646285	rs41306930	CFAP46	G>A	28	13773	19.32	1.108e-05	2.274
chr6:32268488	Affx-28470672	TSBP1	T>C	31	15914	19.29	1.125e-05	2.189
chr11:28988479	rs116969907	-	G>A	37	20267	19.07	1.258e-05	2.052
chr6:31403460	rs61103100	-	C>T	40	22564	18.89	1.384e-05	1.996

Associated Phenotypes ^ⓘ

ID	Name	Top Correlation
HP: 0000713	Agitation	1/20
HP: 0000718	Aggressive behavior	2/20
HP: 0000726	Dementia	1/20
HP: 0000738	Hallucinations	1/20
HP: 0001268	Mental deterioration	1/20
HP: 0001289	Confusion	1/20
HP: 0002059	Cerebral atrophy	1/20
HP: 0002119	Ventriculomegaly	1/20
HP: 0002120	Cerebral cortical atrophy	1/20
HP: 0002367	Visual hallucinations	1/20
HP: 0002472	Small cerebral cortex	1/20
HP: 0002511	Alzheimer disease	1/20
HP: 0002538	Abnormality of the cerebral cortex	1/20
HP: 0002977	Aplasia/Hypoplasia involving the central nervous system	1/20
HP: 0003107	Abnormal circulating cholesterol concentration	1/20
HP: 0003119	Abnormal circulating lipid concentration	1/20
HP: 0004372	Reduced consciousness/confusion	1/20
HP: 0007343	Abnormal morphology of the limbic system	1/20
HP: 0007367	Atrophy/Degeneration affecting the central nervous system	1/20
HP: 0007369	Atrophy/Degeneration affecting the cerebrum	1/20
HP: 0008760	Violent behavior	2/20
HP: 0012444	Brain atrophy	1/20
HP: 0025100	Abnormal morphology of the hippocampus	1/20
HP: 0031258	Delirium	1/20
HP: 0410170	Hippocampal atrophy	1/20

Name

Top Correlation

1/20

2/20

1/20

1/20

1/20

1/20

1/20

1/20

Cerebral cortical atrophy

1/20

HP: 0002367

Visual hallucinations

1/20

HP: 0002472

Small cerebral cortex

1/20

HP: 0002511

Alzheimer disease

1/20

HP: 0002538

Abnormality of the cerebral cortex

1/20

HP: 0002977

Aplasia/Hypoplasia involving the central nervous system

1/20

HP: 0003107

Abnormal circulating cholesterol concentration

1/20

HP: 0003119

Abnormal circulating lipid concentration

1/20

HP: 0004372

Reduced consciousness/confusion

1/20

HP: 0007343

Abnormal morphology of the limbic system

1/20

HP: 0007367

Atrophy/Degeneration affecting the central nervous system

1/20

HP: 0007369

Atrophy/Degeneration affecting the cerebrum

1/20

2/20

1/20

Abnormal morphology of the hippocampus

1/20

1/20

1/20

ID	Name	Top Correlation
HP: 0000118	Phenotypic abnormality	0/20
HP: 0000152	Abnormality of head or neck	0/20
HP: 0000234	Abnormality of the head	0/20
HP: 0000271	Abnormality of the face	0/20
HP: 0000478	Abnormality of the eye	0/20
HP: 0000504	Abnormality of vision	0/20
HP: 0000505	Visual impairment	0/20
HP: 0000707	Abnormality of the nervous system	0/20
HP: 0000708	Behavioral abnormality	0/20
HP: 0000709	Psychosis	0/20
HP: 0000711	Restlessness	0/20
HP: 0000719	Inappropriate behavior	0/20
HP: 0000729	Autistic behavior	0/20
HP: 0000735	Impaired social interactions	0/20
HP: 0000736	Short attention span	0/20
HP: 0000739	Anxiety	0/20
HP: 0000746	Delusions	0/20
HP: 0000752	Hyperactivity	0/20
HP: 0000756	Agoraphobia	0/20
HP: 0000836	Hyperthyroidism	0/20
HP: 0000864	Abnormality of the hypothalamus-pituitary axis	0/20
HP: 0000924	Abnormality of the skeletal system	0/20
HP: 0000951	Abnormality of the skin	0/20
HP: 0001123	Visual field defect	0/20
HP: 0001249	Intellectual disability	0/20
HP: 0001256	Intellectual disability, mild	0/20
HP: 0001317	Abnormal cerebellum morphology	0/20
HP: 0001574	Abnormality of the integument	0/20
HP: 0001575	Mood changes	0/20
HP: 0001626	Abnormality of the cardiovascular system	0/20
HP: 0001939	Abnormality of metabolism/homeostasis	0/20
HP: 0002011	Morphological central nervous system abnormality	0/20
HP: 0002060	Abnormal cerebral morphology	0/20
HP: 0002118	Abnormality of the cerebral ventricles	0/20
HP: 0002134	Abnormality of the basal ganglia	0/20
HP: 0002135	Basal ganglia calcification	0/20
HP: 0002354	Memory impairment	0/20
HP: 0002463	Language impairment	0/20
HP: 0002514	Cerebral calcification	0/20
HP: 0002597	Abnormality of the vasculature	0/20
HP: 0002664	Neoplasm	0/20
HP: 0002858	Meningioma	0/20
HP: 0002925	Increased thyroid-stimulating hormone level	0/20
HP: 0002926	Abnormality of thyroid physiology	0/20
HP: 0003146	Hypocholesterolemia	0/20
HP: 0004375	Neoplasm of the nervous system	0/20
HP: 0006919	Abnormal aggressive, impulsive or violent behavior	0/20
HP: 0007018	Attention deficit hyperactivity disorder	0/20
HP: 0007302	Bipolar affective disorder	0/20
HP: 0008768	Inappropriate sexual behavior	0/20
HP: 0010766	Ectopic calcification	0/20
HP: 0010783	Erythema	0/20
HP: 0010865	Oppositional defiant disorder	0/20
HP: 0010993	Abnormality of the cerebral subcortex	0/20
HP: 0011121	Abnormality of skin morphology	0/20
HP: 0011276	Vascular skin abnormality	0/20
HP: 0011282	Abnormality of hindbrain morphology	0/20
HP: 0011283	Abnormality of the metencephalon	0/20
HP: 0011354	Generalized abnormality of skin	0/20
HP: 0011446	Abnormality of higher mental function	0/20
HP: 0011793	Neoplasm by anatomical site	0/20
HP: 0012075	Personality disorder	0/20
HP: 0012373	Abnormal eye physiology	0/20
HP: 0012433	Abnormal social behavior	0/20
HP: 0012443	Abnormality of brain morphology	0/20
HP: 0012503	Abnormality of the pituitary gland	0/20
HP: 0012638	Abnormal nervous system physiology	0/20
HP: 0012639	Abnormal nervous system morphology	0/20
HP: 0012759	Neurodevelopmental abnormality	0/20
HP: 0025142	Constitutional symptom	0/20
HP: 0025406	Asthenia	0/20
HP: 0030214	Hypersexuality	0/20
HP: 0030215	Inappropriate crying	0/20
HP: 0031072	Abnormal endocrine physiology	0/20
HP: 0031097	Abnormal thyroid-stimulating hormone level	0/20
HP: 0031180	Erythema migrans	0/20
HP: 0031466	Impairment in personality functioning	0/20
HP: 0031589	Suicidal ideation	0/20
HP: 0031943	Akathisia	0/20
HP: 0031987	Diminished ability to concentrate	0/20
HP: 0032180	Abnormal circulating metabolite concentration	0/20
HP: 0045014	Hypolipidemia	0/20
HP: 0100006	Neoplasm of the central nervous system	0/20
HP: 0100022	Abnormality of movement	0/20
HP: 0100543	Cognitive impairment	0/20
HP: 0100547	Abnormality of forebrain morphology	0/20
HP: 0100753	Schizophrenia	0/20
HP: 0100754	Mania	0/20
HP: 0100835	Benign neoplasm of the central nervous system	0/20
HP: 0100851	Abnormal emotion/affect behavior	0/20
HP: 0100852	Abnormal fear/anxiety-related behavior	0/20

Name

Top Correlation

HP: 0000118

Phenotypic abnormality

0/20

HP: 0000152

Abnormality of head or neck

0/20

HP: 0000234

Abnormality of the head

0/20

HP: 0000271