I08.0

Case	Control
785	459420

Case

Control

785

459420

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds Ratio
chr1:62716853	rs72681429	KANK4	C>T	50	15018	24.41	7.796e-07	2.007
chr16:83683945	rs11859365	CDH13	A>C	505	248817	23.26	1.412e-06	1.294
chr10:92733574	rs74472826	-	T>C	75	25943	22.96	1.655e-06	1.75
chr9:6664708	rs1755618	-	G>T	304	141636	21.32	3.891e-06	1.34
chr18:14265742	rs11872100	-	C>G	242	188174	21.18	4.171e-06	0.7265
chr4:180611159	rs76495583	-	A>G	59	19519	21.05	4.476e-06	1.823
chr2:139416621	rs116521994	-	G>A	91	33900	20.99	4.609e-06	1.632
chr7:73126224	rs117943116	STX1A	G>A	71	24874	20.91	4.816e-06	1.732
chr4:155628395	rs4696602	LRAT	C>A	124	49998	19.8	8.62e-06	1.512
chr17:5334186	rs4427854	RPAIN	G>C	68	24215	18.73	1.505e-05	1.7
chr2:169645346	rs116248616	NOSTRIN	A>G	48	15534	18.72	1.511e-05	1.868
chr1:205391677	rs35607136	LEMD1	T>C	240	109927	18.33	1.857e-05	1.348
chr3:50420554	rs2236950	CACNA2D2	C>A	352	169908	18.31	1.875e-05	1.293
chr21:34456502	rs73202460	-	T>C	74	70732	18.25	1.935e-05	0.6045
chr11:117779305	rs80264810	TMPRSS13	C>A	62	61593	18.22	1.969e-05	0.5792
chr8:11853121	rs73195062	DEFB134	C>T	52	17292	18.2	1.985e-05	1.81
chr6:98926295	rs117673232	-	C>T	55	18554	18.2	1.989e-05	1.782
chr6:141886726	rs77995889	-	G>C	76	27957	18.17	2.023e-05	1.642
chr7:129931774	rs75222399	-	A>G	207	92834	18.15	2.039e-05	1.371
chr8:8424632	rs113841996	-	C>T	70	25324	18.0	2.212e-05	1.671

Associated Phenotypes ^ⓘ

ID	Name	Top Correlation
HP: 0005180	Tricuspid regurgitation	2/20
HP: 0010446	Tricuspid stenosis	3/20
HP: 0031651	Abnormal tricuspid valve physiology	3/20

Name

Top Correlation

2/20

3/20

3/20

ID	Name	Top Correlation
HP: 0000118	Phenotypic abnormality	0/20
HP: 0001626	Abnormality of the cardiovascular system	0/20
HP: 0001627	Abnormal heart morphology	0/20
HP: 0001633	Abnormal mitral valve morphology	0/20
HP: 0001653	Mitral regurgitation	0/20
HP: 0001654	Abnormal heart valve morphology	0/20
HP: 0001659	Aortic regurgitation	0/20
HP: 0001702	Abnormal tricuspid valve morphology	0/20
HP: 0001718	Mitral stenosis	0/20
HP: 0002086	Abnormality of the respiratory system	0/20
HP: 0002597	Abnormality of the vasculature	0/20
HP: 0002795	Functional respiratory abnormality	0/20
HP: 0006705	Abnormal atrioventricular valve morphology	0/20
HP: 0011025	Abnormal cardiovascular system physiology	0/20
HP: 0030163	Abnormal vascular physiology	0/20
HP: 0030680	Abnormality of cardiovascular system morphology	0/20
HP: 0030875	Abnormality of pulmonary circulation	0/20
HP: 0030950	Pulmonary venous hypertension	0/20
HP: 0031481	Abnormal mitral valve physiology	0/20
HP: 0031650	Abnormal atrioventricular valve physiology	0/20
HP: 0031652	Abnormal aortic valve physiology	0/20
HP: 0031653	Abnormal heart valve physiology	0/20

Name

Top Correlation

0/20

0/20

0/20