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ICD-10
HPO
Compare GWAS
Super Class
Chronic ischaemic heart disease
Sub Class
Other forms of chronic ischaemic heart disease
I25.8
Case/Control GWAS
ⓘ
Links
Sex Split
Interactive Plot
Statistics
Case
Control
8163
452042
Top SNP Information
Show Table
Location
SNP
Gene
Ref>Alt
Alt in Case
Alt in Control
Chi-square
P-value
Odds Ratio
chr6:161010118
rs10455872
LPA
A>G
1747
71954
153.5
3.04e-35
1.37
chr9:22098574
rs4977574
-
A>G
9215
461219
148.8
3.173e-34
1.205
chr9:22096055
rs10757274
-
A>G
9255
463310
148.2
4.203e-34
1.205
chr6:160997118
rs74617384
LPA
A>T
1699
70130
147.8
5.218e-34
1.367
chr9:22124477
rs10757278
-
A>G
9131
456982
145.5
1.668e-33
1.202
chr9:22125503
rs1333049
-
G>C
9135
457316
143.6
4.387e-33
1.201
chr9:22088260
rs10757272
-
C>T
9222
462539
141.6
1.21e-32
1.2
chr9:22125347
rs1333048
-
A>C
9431
474239
140.7
1.906e-32
1.199
chr9:22003223
rs3217992
AL359922.1
C>T
6978
347334
105.0
1.203e-24
1.173
chr9:22115959
rs2383207
-
G>A
7596
454454
104.7
1.39e-24
0.8542
chr9:22083404
rs1333040
-
T>C
6538
395087
101.9
5.834e-24
0.8529
chr9:22081850
rs6475606
-
C>T
9321
474961
100.8
1.002e-23
1.166
chr8:145639681
rs1871534
SLC39A4
G>C
165
17980
81.41
1.835e-19
0.4991
chr9:22068652
rs4977756
-
A>G
6323
377741
75.19
4.272e-18
0.8713
chr6:12903957
rs9349379
PHACTR1
A>G
7567
384643
72.76
1.462e-17
1.14
chr6:160848743
rs9457925
SLC22A3
G>A
471
17527
71.41
2.909e-17
1.488
chr6:160922870
rs117733303
-
A>G
472
17626
70.4
4.83e-17
1.483
chr1:159174683
rs2814778
ACKR1
T>C
196
19181
68.06
1.582e-16
0.5559
chr9:22029445
rs10965215
AL359922.1
G>A
8770
451695
67.13
2.537e-16
1.133
chr6:160961137
rs3798220
LPA
T>C
459
17298
65.02
7.401e-16
1.468
Associated Phenotypes
ⓘ
Shared SNP phenotypes
No shared SNP phenotypes
ID
Name
Top Correlation
HP: 0000356
Abnormality of the outer ear
6/20
HP: 0000363
Abnormality of earlobe
10/20
HP: 0000377
Abnormality of the pinna
10/20
HP: 0000598
Abnormality of the ear
2/20
HP: 0001649
Tachycardia
2/20
HP: 0001681
Angina pectoris
17/20
HP: 0001939
Abnormality of metabolism/homeostasis
2/20
HP: 0003077
Hyperlipidemia
2/20
HP: 0003107
Abnormal circulating cholesterol concentration
2/20
HP: 0003119
Abnormal circulating lipid concentration
2/20
HP: 0004756
Ventricular tachycardia
2/20
HP: 0005162
Left ventricular dysfunction
15/20
HP: 0005168
Elevated right atrial pressure
20/20
HP: 0009908
Anterior creases of earlobe
19/20
HP: 0010979
Abnormality of lipoprotein cholesterol concentration
2/20
HP: 0010980
Hyperlipoproteinemia
2/20
HP: 0011675
Arrhythmia
6/20
HP: 0011710
Bundle branch block
15/20
HP: 0011715
Trifascicular block
16/20
HP: 0011841
Ventricular flutter
2/20
HP: 0012722
Heart block
15/20
HP: 0025443
Abnormal cardiac atrial physiology
20/20
HP: 0030872
Abnormal cardiac ventricular function
17/20
HP: 0030956
Abnormality of cardiovascular system electrophysiology
8/20
HP: 0031511
Diagonal earlobe crease
20/20
HP: 0031546
Cardiac conduction abnormality
15/20
HP: 0031703
Abnormal ear morphology
2/20
HP: 0032180
Abnormal circulating metabolite concentration
1/20
ID
Name
Top Correlation
HP: 0000118
Phenotypic abnormality
0/20
HP: 0000152
Abnormality of head or neck
0/20
HP: 0000234
Abnormality of the head
0/20
HP: 0001626
Abnormality of the cardiovascular system
0/20
HP: 0011025
Abnormal cardiovascular system physiology
0/20