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ICD-10
HPO
Compare GWAS
Super Class
Other forms of heart disease
Sub Class
Atrioventricular block, first degree
Atrioventricular block, second degree
Atrioventricular block, complete
Other and unspecified atrioventricular block
Other and unspecified fascicular block
Left bundle-branch block, unspecified
Atrioventricular and left bundle-branch block
I44
Case/Control GWAS
ⓘ
Links
Sex Split
Interactive Plot
Statistics
Case
Control
5595
454599
Top SNP Information
Show Table
Location
SNP
Gene
Ref>Alt
Alt in Case
Alt in Control
Chi-square
P-value
Odds Ratio
chr3:38766675
rs6795970
SCN10A
G>A
4880
374487
36.23
1.751e-09
1.12
chr3:38774832
rs6800541
SCN10A
T>C
4975
382855
35.42
2.664e-09
1.118
chr15:48426484
rs1426654
SLC24A5
A>G
225
27301
35.4
2.681e-09
0.6706
chr3:38767315
rs6801957
SCN10A
C>T
4989
384898
32.82
1.013e-08
1.114
chr9:140957557
rs11137360
CACNA1B
A>G
164
20842
32.23
1.369e-08
0.6411
chr3:391100
rs13060847
CHL1
G>A
77
11577
29.12
6.791e-08
0.5436
chr3:38589163
rs11129795
-
G>A
3035
229094
28.64
8.701e-08
1.12
chr10:105816916
rs805698
COL17A1
T>C
105
14395
28.3
1.039e-07
0.5959
chr12:1684934
rs7976513
WNT5B
G>A
449
47154
28.16
1.117e-07
0.7742
chr2:236294462
rs57088602
-
T>C
306
33851
28.0
1.215e-07
0.7359
chr2:211717706
rs12995612
-
C>G
125
16347
27.7
1.415e-07
0.6245
chr9:127267689
rs3814134
NR5A1
A>G
255
28951
27.45
1.608e-07
0.7177
chr10:75395108
rs73272395
MYOZ1
G>T
1270
119800
27.15
1.885e-07
0.856
chr16:58754888
rs9921563
GOT2
G>A
204
24003
27.05
1.98e-07
0.6929
chr10:25014437
rs11014215
-
G>T
1201
85250
26.68
2.4e-07
1.172
chr13:33991907
rs7319309
-
C>T
168
20447
26.67
2.416e-07
0.6701
chr8:136150965
rs971448
-
T>C
90
12539
25.76
3.861e-07
0.587
chr1:236085940
rs12038310
-
C>T
116
15160
25.66
4.07e-07
0.6249
chr14:89695300
rs116522391
FOXN3
G>A
467
30416
25.63
4.135e-07
1.272
chr7:41427194
rs10257950
-
A>G
194
22714
25.02
5.674e-07
0.6965
Associated Phenotypes
ⓘ
Shared SNP phenotypes
No shared SNP phenotypes
ID
Name
Top Correlation
HP: 0000118
Phenotypic abnormality
3/20
HP: 0001626
Abnormality of the cardiovascular system
2/20
HP: 0001649
Tachycardia
2/20
HP: 0001662
Bradycardia
2/20
HP: 0001678
Atrioventricular block
1/20
HP: 0001688
Sinus bradycardia
2/20
HP: 0003011
Abnormality of the musculature
1/20
HP: 0004308
Ventricular arrhythmia
2/20
HP: 0004756
Ventricular tachycardia
2/20
HP: 0005150
Abnormal atrioventricular conduction
1/20
HP: 0005172
Left posterior fascicular block
2/20
HP: 0011675
Arrhythmia
1/20
HP: 0011702
Abnormal electrophysiology of sinoatrial node origin
1/20
HP: 0011705
First degree atrioventricular block
4/20
HP: 0011706
Second degree atrioventricular block
1/20
HP: 0011708
Mobitz II atrioventricular block
1/20
HP: 0011710
Bundle branch block
1/20
HP: 0011711
Left anterior fascicular block
4/20
HP: 0011712
Right bundle branch block
4/20
HP: 0011713
Left bundle branch block
3/20
HP: 0012722
Heart block
1/20
HP: 0012900
Myotonia of the face
4/20
HP: 0030956
Abnormality of cardiovascular system electrophysiology
2/20
HP: 0031546
Cardiac conduction abnormality
1/20
ID
Name
Top Correlation
HP: 0001709
Third degree atrioventricular block
0/20
HP: 0002486
Myotonia
0/20
HP: 0005155
Ventricular escape rhythm
0/20
HP: 0005178
Complete heart block with narrow QRS complexes
0/20
HP: 0011025
Abnormal cardiovascular system physiology
0/20
HP: 0011715
Trifascicular block
0/20
HP: 0011804
Abnormal muscle physiology
0/20
HP: 0031675
Fascicular left ventricular tachycardia
0/20