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ICD-10
HPO
Compare GWAS
Super Class
Other peripheral vascular diseases
Sub Class
Raynaud's syndrome
I73.0
Case/Control GWAS
ⓘ
Links
Sex Split
Interactive Plot
Statistics
Case
Control
1650
458555
Top SNP Information
Show Table
Location
SNP
Gene
Ref>Alt
Alt in Case
Alt in Control
Chi-square
P-value
Odds Ratio
chr10:112860526
rs1343449
-
A>G
1324
317288
48.53
3.25e-12
1.276
chr5:4029789
rs11748327
-
C>T
1179
287871
32.84
1.003e-08
1.228
chr10:112862029
rs945333
-
T>C
1869
481746
27.37
1.681e-07
1.196
chr10:124235355
rs2672587
HTRA1
C>G
716
236268
24.61
7.035e-07
0.8121
chr6:99877219
rs6923983
-
T>G
1428
439578
22.9
1.709e-06
0.8475
chr6:31434621
rs3131618
-
A>G
559
130031
22.62
1.979e-06
1.246
chr6:31129310
rs7750641
TCF19
C>T
602
141480
22.6
1.99e-06
1.238
chr6:31492453
rs3093988
-
G>A
736
176305
22.39
2.223e-06
1.217
chr16:11631394
rs76554681
-
C>T
126
23358
22.38
2.237e-06
1.533
chr6:31434366
rs3094013
-
G>A
565
132223
21.68
3.224e-06
1.239
chr6:31417191
rs3128982
-
A>G
1287
324910
21.51
3.523e-06
1.177
chr5:2640901
rs434848
-
T>C
849
207206
21.05
4.479e-06
1.199
chr6:31430694
rs3094605
-
G>C
564
132289
20.88
4.884e-06
1.234
chr6:31418070
rs3099836
-
A>C
1283
324563
20.71
5.347e-06
1.174
chr2:240054995
rs73000137
HDAC4
C>G
543
182024
20.47
6.06e-06
0.8094
chr6:31060219
rs2535296
-
A>G
729
175965
20.4
6.295e-06
1.207
chr5:56301157
rs17732475
-
C>T
1430
439214
20.28
6.674e-06
0.8558
chr2:168101386
rs76672761
XIRP2
G>A
135
25942
20.06
7.492e-06
1.48
chr6:31506210
rs3093974
ATP6V1G2-DDX39B
G>A
1365
348245
19.7
9.062e-06
1.167
chr21:40900002
rs118111352
-
A>G
129
24658
19.62
9.442e-06
1.486
Associated Phenotypes
ⓘ
Shared SNP phenotypes
No shared SNP phenotypes
ID
Name
Top Correlation
HP: 0000961
Cyanosis
1/20
HP: 0001063
Acrocyanosis
1/20
HP: 0003761
Calcinosis
4/20
HP: 0011838
Sclerodactyly
1/20
HP: 0025300
Malar rash
6/20
HP: 0030880
Raynaud phenomenon
2/20
HP: 0031293
Digital pitting scar
12/20
HP: 0100276
Skin pit
2/20
HP: 0100324
Scleroderma
8/20
HP: 0550003
Proximal scleroderma
10/20
ID
Name
Top Correlation
HP: 0000118
Phenotypic abnormality
0/20
HP: 0000924
Abnormality of the skeletal system
0/20
HP: 0000951
Abnormality of the skin
0/20
HP: 0000988
Skin rash
0/20
HP: 0001005
Dermatological manifestations of systemic disorders
0/20
HP: 0001072
Thickened skin
0/20
HP: 0001155
Abnormality of the hand
0/20
HP: 0001167
Abnormality of finger
0/20
HP: 0001574
Abnormality of the integument
0/20
HP: 0001626
Abnormality of the cardiovascular system
0/20
HP: 0002086
Abnormality of the respiratory system
0/20
HP: 0002597
Abnormality of the vasculature
0/20
HP: 0002715
Abnormality of the immune system
0/20
HP: 0002795
Functional respiratory abnormality
0/20
HP: 0002813
Abnormality of limb bone morphology
0/20
HP: 0002817
Abnormality of the upper limb
0/20
HP: 0003011
Abnormality of the musculature
0/20
HP: 0010978
Abnormality of immune system physiology
0/20
HP: 0011025
Abnormal cardiovascular system physiology
0/20
HP: 0011121
Abnormality of skin morphology
0/20
HP: 0011122
Abnormality of skin physiology
0/20
HP: 0011123
Inflammatory abnormality of the skin
0/20
HP: 0011297
Abnormal digit morphology
0/20
HP: 0011354
Generalized abnormality of skin
0/20
HP: 0011355
Localized skin lesion
0/20
HP: 0011805
Abnormal skeletal muscle morphology
0/20
HP: 0011842
Abnormality of skeletal morphology
0/20
HP: 0011844
Abnormal appendicular skeleton morphology
0/20
HP: 0012647
Abnormal inflammatory response
0/20
HP: 0012649
Increased inflammatory response
0/20
HP: 0025131
Finger swelling
0/20
HP: 0025323
Abnormal arterial physiology
0/20
HP: 0030163
Abnormal vascular physiology
0/20
HP: 0031917
Digital ulcer
0/20
HP: 0040064
Abnormality of limbs
0/20
HP: 0040068
Abnormality of limb bone
0/20
HP: 0200042
Skin ulcer
0/20