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ICD-10
HPO
Compare GWAS
Super Class
Acute tonsillitis
Sub Class
Acute tonsillitis, unspecified
J03.9
Case/Control GWAS
ⓘ
Links
Sex Split
Interactive Plot
Statistics
Case
Control
673
459532
Top SNP Information
Show Table
Location
SNP
Gene
Ref>Alt
Alt in Case
Alt in Control
Chi-square
P-value
Odds Ratio
chr1:159174683
rs2814778
ACKR1
T>C
83
19294
92.97
5.319e-22
2.837
chr10:114925758
rs1056877
TCF7L2
T>C
60
12391
85.09
2.853e-20
3.167
chr17:58508582
rs8071181
C17orf64
G>A
69
15348
84.84
3.239e-20
2.955
chr12:132549300
rs7136109
EP400
A>G
54
10576
84.68
3.501e-20
3.334
chr9:127267689
rs3814134
NR5A1
A>G
102
29104
71.11
3.371e-17
2.318
chr16:12645933
rs4781251
SNX29
A>C
86
23211
68.69
1.151e-16
2.439
chr10:117649124
rs7904803
ATRNL1
C>A
74
18612
68.22
1.46e-16
2.589
chr6:37328215
Affx-28571852
RNF8
C>CT
75
19241
67.28
2.351e-16
2.556
chr17:29298304
rs7225888
RNF135
C>G
76
19859
65.29
6.465e-16
2.509
chr6:137344363
rs1744080
IL20RA
G>A
67
16544
65.22
6.702e-16
2.644
chr19:42393286
rs717225
ARHGEF1
A>G
81
21862
64.55
9.398e-16
2.434
chr1:173579034
rs12065033
AL139142.2
C>T
63
15278
64.33
1.052e-15
2.699
chr8:145639681
rs1871534
SLC39A4
G>C
70
18075
62.2
3.103e-15
2.542
chr1:12753203
rs11121959
-
T>C
68
17446
60.86
6.141e-15
2.548
chr10:31512098
rs2484992
-
C>T
82
22827
60.56
7.126e-15
2.359
chr13:33991907
rs7319309
-
C>T
76
20539
60.32
8.077e-15
2.426
chr4:40561143
rs73147591
RBM47
T>G
48
10568
59.8
1.052e-14
2.953
chr10:31515132
rs2484990
-
C>T
82
23010
59.23
1.4e-14
2.338
chr17:29290106
rs55861543
-
C>T
76
20683
59.06
1.53e-14
2.405
chr6:3185712
rs7754077
-
C>T
70
18602
58.07
2.531e-14
2.467
Associated Phenotypes
ⓘ
Shared SNP phenotypes
No shared SNP phenotypes
ID
Name
Top Correlation
HP: 0000370
Abnormality of the middle ear
1/20
HP: 0000598
Abnormality of the ear
5/20
HP: 0000600
Abnormality of the pharynx
1/20
HP: 0001739
Abnormality of the nasopharynx
6/20
HP: 0002205
Recurrent respiratory infections
5/20
HP: 0002788
Recurrent upper respiratory tract infections
7/20
HP: 0011110
Tonsillitis
2/20
HP: 0025439
Pharyngitis
2/20
HP: 0030812
Enlarged tonsils
2/20
HP: 0031458
Adenoiditis
7/20
HP: 0031703
Abnormal ear morphology
3/20
HP: 0100763
Abnormality of the lymphatic system
1/20
HP: 0100765
Abnormality of the tonsils
1/20
HP: 0100776
Recurrent pharyngitis
6/20
HP: 3000033
Abnormality of nasopharyngeal adenoids
7/20
ID
Name
Top Correlation
HP: 0000118
Phenotypic abnormality
0/20
HP: 0000152
Abnormality of head or neck
0/20
HP: 0000234
Abnormality of the head
0/20
HP: 0000271
Abnormality of the face
0/20
HP: 0000366
Abnormality of the nose
0/20
HP: 0000388
Otitis media
0/20
HP: 0001626
Abnormality of the cardiovascular system
0/20
HP: 0002086
Abnormality of the respiratory system
0/20
HP: 0002088
Abnormal lung morphology
0/20
HP: 0002597
Abnormality of the vasculature
0/20
HP: 0002715
Abnormality of the immune system
0/20
HP: 0002719
Recurrent infections
0/20
HP: 0010978
Abnormality of immune system physiology
0/20
HP: 0011947
Respiratory tract infection
0/20
HP: 0012252
Abnormal respiratory system morphology
0/20
HP: 0012387
Bronchitis
0/20
HP: 0012388
Acute bronchitis
0/20
HP: 0012647
Abnormal inflammatory response
0/20
HP: 0012649
Increased inflammatory response
0/20
HP: 0025031
Abnormality of the digestive system
0/20
HP: 0025033
Abnormality of digestive system morphology
0/20
HP: 0032101
Unusual infection
0/20