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ICD-10
HPO
Compare GWAS
Super Class
Other chronic obstructive pulmonary disease
Sub Class
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
J44.1
Case/Control GWAS
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Links
Sex Split
Interactive Plot
Statistics
Case
Control
1553
458652
Top SNP Information
Show Table
Location
SNP
Gene
Ref>Alt
Alt in Case
Alt in Control
Chi-square
P-value
Odds Ratio
chr15:78882925
rs16969968
CHRNA5
G>A
1208
312186
41.63
1.105e-10
1.264
chr15:78878541
rs951266
CHRNA5
G>A
1208
312373
40.28
2.195e-10
1.259
chr15:78868636
rs72740964
CHRNA5
G>A
1194
308086
40.15
2.351e-10
1.26
chr15:78873993
rs7180002
CHRNA5
A>T
1205
312288
38.6
5.204e-10
1.254
chr15:78857939
rs55853698
CHRNA5
T>G
1216
316199
38.22
6.318e-10
1.252
chr15:78894339
rs1051730
CHRNA3
G>A
1202
312944
38.07
6.837e-10
1.252
chr15:78911672
rs4243084
CHRNA3
G>C
1231
321484
36.92
1.232e-09
1.246
chr15:78896129
rs1317286
CHRNA3
A>G
1223
318869
36.79
1.317e-09
1.246
chr15:78898723
rs12914385
CHRNA3
C>T
1375
363589
35.92
2.056e-09
1.238
chr15:78867482
rs17486278
CHRNA5
A>C
1216
318707
34.03
5.426e-09
1.236
chr15:78857986
rs55781567
CHRNA5
C>G
1218
320102
33.81
6.086e-09
1.235
chr15:78806023
rs8034191
HYKK
T>C
1211
318211
32.47
1.213e-08
1.23
chr11:68817229
rs4930259
TPCN2
T>C
15
17468
32.38
1.269e-08
0.2554
chr15:78911181
rs8040868
CHRNA3
T>C
1413
377558
31.93
1.598e-08
1.222
chr6:31009055
rs2517546
-
C>T
635
156093
31.05
2.513e-08
1.28
chr15:78930510
rs1316971
CHRNB4
G>A
558
206693
31.03
2.545e-08
0.7719
chr15:48426484
rs1426654
SLC24A5
A>G
39
27487
30.91
2.702e-08
0.4195
chr15:78783277
rs11858836
IREB2
G>A
1143
301256
30.51
3.324e-08
1.226
chr15:78814046
rs10519203
HYKK
A>G
1225
323189
30.48
3.375e-08
1.222
chr9:140957557
rs11137360
CACNA1B
A>G
25
20981
29.41
5.867e-08
0.3529
Associated Phenotypes
ⓘ
Shared SNP phenotypes
No shared SNP phenotypes
ID
Name
Top Correlation
HP: 0000118
Phenotypic abnormality
1/20
HP: 0000707
Abnormality of the nervous system
1/20
HP: 0001289
Confusion
2/20
HP: 0002086
Abnormality of the respiratory system
1/20
HP: 0002087
Abnormality of the upper respiratory tract
1/20
HP: 0002088
Abnormal lung morphology
1/20
HP: 0002093
Respiratory insufficiency
13/20
HP: 0002110
Bronchiectasis
3/20
HP: 0002715
Abnormality of the immune system
1/20
HP: 0002878
Respiratory failure
7/20
HP: 0004372
Reduced consciousness/confusion
2/20
HP: 0005607
Abnormal tracheobronchial morphology
1/20
HP: 0006510
Chronic obstructive pulmonary disease
1/20
HP: 0006536
Obstructive lung disease
2/20
HP: 0010978
Abnormality of immune system physiology
1/20
HP: 0011947
Respiratory tract infection
1/20
HP: 0012252
Abnormal respiratory system morphology
1/20
HP: 0012387
Bronchitis
1/20
HP: 0012388
Acute bronchitis
1/20
HP: 0025426
Abnormal bronchus morphology
1/20
HP: 0031258
Delirium
2/20
HP: 0100845
Anaphylactic shock
1/20
ID
Name
Top Correlation
HP: 0002795
Functional respiratory abnormality
0/20
HP: 0011446
Abnormality of higher mental function
0/20
HP: 0012638
Abnormal nervous system physiology
0/20
HP: 0100326
Immunologic hypersensitivity
0/20