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ICD-10
HPO
Compare GWAS
Super Class
Pleural plaque
Sub Class
Pleural plaque with presence of asbestos
J92.0
Case/Control GWAS
ⓘ
Links
Sex Split
Interactive Plot
Statistics
Case
Control
619
459586
Top SNP Information
Show Table
Location
SNP
Gene
Ref>Alt
Alt in Case
Alt in Control
Chi-square
P-value
Odds Ratio
chr5:33951693
rs16891982
SLC45A2
G>C
37
67024
30.53
3.293e-08
0.4097
chr6:31883957
rs644045
C2
G>A
564
363052
30.45
3.43e-08
1.366
chr7:9215320
Affx-31094974
-
C>G
64
25628
29.36
6.018e-08
1.979
chr10:18301381
rs12781325
SLC39A12
T>C
60
23833
28.42
9.772e-08
1.998
chr6:31919578
rs2072633
AL645922.1
G>A
677
452775
27.4
1.653e-07
1.344
chr15:65553246
rs2304896
PARP16
C>T
434
274003
26.79
2.268e-07
1.359
chr5:33958959
rs28777
SLC45A2
A>C
31
56964
26.19
3.099e-07
0.4065
chr6:30879636
rs886420
GTF2H4
C>T
239
138433
23.59
1.191e-06
1.416
chr5:159530846
rs12520657
PWWP2A
T>C
67
29093
23.49
1.253e-06
1.822
chr6:136865580
rs926400
MAP7
C>T
170
92881
22.86
1.745e-06
1.48
chr21:40369159
rs2836816
-
C>A
465
425361
22.84
1.756e-06
0.7569
chr6:31893944
rs2734335
C2
G>A
509
458839
22.55
2.044e-06
0.7618
chr6:30882415
rs1264304
VARS2
C>T
240
140203
22.39
2.221e-06
1.403
chr22:41054954
rs117871311
-
G>A
66
28996
22.29
2.345e-06
1.802
chr6:30802465
rs1264341
-
T>C
240
140247
22.16
2.503e-06
1.4
chr6:30838497
rs2535340
-
T>C
240
140181
22.13
2.552e-06
1.4
chr6:30864279
rs886422
DDR1
C>T
240
140263
22.12
2.555e-06
1.4
chr3:2726819
rs13062362
CNTN4
G>A
385
359895
22.12
2.563e-06
0.7506
chr6:30857894
rs1264322
DDR1
G>A
240
140319
22.08
2.617e-06
1.399
chr4:169974291
rs114742385
-
G>A
48
19239
21.97
2.768e-06
1.969
Associated Phenotypes
ⓘ
Shared SNP phenotypes
No shared SNP phenotypes
ID
Name
Top Correlation
HP: 0000118
Phenotypic abnormality
1/20
HP: 0001746
Asplenia
2/20
HP: 0002202
Pleural effusion
1/20
HP: 0002664
Neoplasm
2/20
HP: 0010451
Aplasia/Hypoplasia of the spleen
2/20
HP: 0011793
Neoplasm by anatomical site
2/20
HP: 0011921
Exudative pleural effusion
2/20
HP: 0012337
Abnormal homeostasis
2/20
HP: 0025176
Intralobular interstitial thickening
3/20
HP: 0025177
Peribronchovascular interstitial thickening
1/20
HP: 0031944
Pleural thickening
2/20
HP: 0032341
Reduced forced vital capacity
3/20
HP: 0100001
Malignant mesothelioma
2/20
HP: 0100002
Pleural mesothelioma
2/20
HP: 0100004
Pericardial mesothelioma
3/20
HP: 0100527
Neoplasia of the pleura
2/20
HP: 0100606
Neoplasm of the respiratory system
2/20
ID
Name
Top Correlation
HP: 0000969
Edema
0/20
HP: 0001626
Abnormality of the cardiovascular system
0/20
HP: 0001627
Abnormal heart morphology
0/20
HP: 0001697
Abnormal pericardium morphology
0/20
HP: 0001743
Abnormality of the spleen
0/20
HP: 0001939
Abnormality of metabolism/homeostasis
0/20
HP: 0002012
Abnormality of the abdominal organs
0/20
HP: 0002086
Abnormality of the respiratory system
0/20
HP: 0002088
Abnormal lung morphology
0/20
HP: 0002102
Pleuritis
0/20
HP: 0002103
Abnormality of the pleura
0/20
HP: 0002597
Abnormality of the vasculature
0/20
HP: 0002715
Abnormality of the immune system
0/20
HP: 0002795
Functional respiratory abnormality
0/20
HP: 0006530
Interstitial pulmonary abnormality
0/20
HP: 0011032
Abnormality of fluid regulation
0/20
HP: 0012252
Abnormal respiratory system morphology
0/20
HP: 0025031
Abnormality of the digestive system
0/20
HP: 0025033
Abnormality of digestive system morphology
0/20
HP: 0025408
Abnormal spleen morphology
0/20
HP: 0030680
Abnormality of cardiovascular system morphology
0/20
HP: 0030878
Abnormality on pulmonary function testing
0/20
HP: 0032340
Abnormal spirometry test
0/20
HP: 0100763
Abnormality of the lymphatic system
0/20