K22.4

Case	Control
650	459555

Case

Control

650

459555

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds Ratio
chr11:7764310	rs78614100	-	A>G	69	28081	22.26	2.386e-06	1.778
chr16:56111361	rs74596009	-	A>G	59	23054	21.63	3.311e-06	1.841
chr5:80894982	rs2972241	SSBP2	A>C	432	252168	21.57	3.408e-06	1.309
chr10:16181515	rs77447490	-	A>G	41	14420	21.48	3.573e-06	2.056
chr18:74886502	rs35644804	-	C>T	83	35622	21.32	3.893e-06	1.678
chr7:117605809	rs73220105	-	C>T	48	17717	21.15	4.257e-06	1.943
chr4:27261875	rs1386903	-	C>T	184	175690	20.38	6.349e-06	0.7006
chr21:25221327	rs207545	-	C>T	194	101539	19.96	7.91e-06	1.412
chr1:181334638	rs114186461	CACNA1E	C>T	95	43021	19.68	9.153e-06	1.597
chr2:184064736	rs192338194	-	C>T	32	10539	19.67	9.227e-06	2.17
chr8:8324418	rs113743386	-	C>T	39	13851	19.46	1.026e-05	2.02
chr4:153291346	rs114121870	FBXW7	A>G	95	44474	19.04	1.281e-05	1.587
chr4:104107655	rs6847357	CENPE	C>G	204	189420	19.02	1.293e-05	0.7193
chr8:109215910	rs617285	EIF3E	T>C	372	214780	18.99	1.314e-05	1.302
chr8:75535579	rs118142415	-	G>A	103	47925	18.98	1.319e-05	1.558
chr4:165968073	rs6814515	-	T>C	53	66242	18.93	1.356e-05	0.5484
chr9:25558868	rs1537265	-	G>A	755	474782	18.76	1.485e-05	1.266
chr18:3170958	rs35331620	MYOM1	C>T	125	60571	18.7	1.53e-05	1.497
chr4:104026547	rs2720447	CENPE	C>T	204	189627	18.56	1.643e-05	0.722
chr4:104059542	rs2243682	CENPE	G>A	205	189152	18.54	1.666e-05	0.7228

Associated Phenotypes ^ⓘ

Name

Top Correlation

ID	Name	Top Correlation
HP: 0000118	Phenotypic abnormality	0/20
HP: 0000707	Abnormality of the nervous system	0/20
HP: 0000951	Abnormality of the skin	0/20
HP: 0001072	Thickened skin	0/20
HP: 0001574	Abnormality of the integument	0/20
HP: 0001626	Abnormality of the cardiovascular system	0/20
HP: 0002012	Abnormality of the abdominal organs	0/20
HP: 0002015	Dysphagia	0/20
HP: 0002020	Gastroesophageal reflux	0/20
HP: 0002571	Achalasia	0/20
HP: 0002577	Abnormality of the stomach	0/20
HP: 0002579	Gastrointestinal dysmotility	0/20
HP: 0002597	Abnormality of the vasculature	0/20
HP: 0003011	Abnormality of the musculature	0/20
HP: 0003761	Calcinosis	0/20
HP: 0011024	Abnormality of the gastrointestinal tract	0/20
HP: 0011025	Abnormal cardiovascular system physiology	0/20
HP: 0011121	Abnormality of skin morphology	0/20
HP: 0011805	Abnormal skeletal muscle morphology	0/20
HP: 0011838	Sclerodactyly	0/20
HP: 0012638	Abnormal nervous system physiology	0/20
HP: 0012718	Morphological abnormality of the gastrointestinal tract	0/20
HP: 0012719	Functional abnormality of the gastrointestinal tract	0/20
HP: 0025031	Abnormality of the digestive system	0/20
HP: 0025032	Abnormality of digestive system physiology	0/20
HP: 0025033	Abnormality of digestive system morphology	0/20
HP: 0025270	Abnormality of esophagus physiology	0/20
HP: 0025323	Abnormal arterial physiology	0/20
HP: 0030163	Abnormal vascular physiology	0/20
HP: 0030880	Raynaud phenomenon	0/20
HP: 0030895	Abnormal gastrointestinal motility	0/20
HP: 0030914	Abnormal peristalsis	0/20
HP: 0031857	Ineffective esophageal peristalsis	0/20
HP: 0100771	Hypoperistalsis	0/20

Name

Top Correlation

HP: 0000118

Phenotypic abnormality

0/20

HP: 0000707

Abnormality of the nervous system

0/20

HP: 0000951

Abnormality of the skin

0/20

HP: 0001072