Statistics
| Female Case | Female Control | % Female |
|---|---|---|
| 439 | 249424 | 32% |
| Male Case | Male Control | % Male |
|---|---|---|
| 952 | 209390 | 68% |
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr3:64360582 | rs61413894 | PRICKLE2 | T>C | 48 | 13735 | 22.14 | 2.539e-06 | 1.983 |
| chr18:13029986 | rs116020861 | CEP192 | G>A | 25 | 5647 | 21.73 | 3.135e-06 | 2.496 |
| chr15:89269152 | rs7179405 | - | G>A | 78 | 26003 | 21.66 | 3.249e-06 | 1.723 |
| chr8:105587265 | rs77575435 | LRP12 | C>G | 40 | 10892 | 21.44 | 3.645e-06 | 2.081 |
| chr3:134007690 | rs75709799 | - | T>C | 25 | 5670 | 21.34 | 3.849e-06 | 2.477 |
| chr4:83851902 | rs115370532 | LIN54 | T>C | 46 | 13144 | 21.3 | 3.93e-06 | 1.984 |
| chr11:133423245 | rs12292311 | - | T>C | 105 | 38080 | 20.64 | 5.532e-06 | 1.594 |
| chr20:56777439 | rs6128287 | - | C>T | 223 | 94287 | 20.57 | 5.761e-06 | 1.413 |
| chr20:56767773 | rs609597 | - | C>T | 521 | 249140 | 20.17 | 7.076e-06 | 1.338 |
| chr3:174681060 | rs10513728 | NAALADL2 | A>G | 26 | 6167 | 20.01 | 7.72e-06 | 2.373 |
| chr21:41583645 | rs11335494 | DSCAM | CA>C | 86 | 29922 | 19.93 | 8.04e-06 | 1.649 |
| chr6:27531570 | rs76833486 | - | C>T | 69 | 22761 | 19.85 | 8.377e-06 | 1.735 |
| chr7:9659078 | rs34036504 | - | C>A | 124 | 47354 | 19.37 | 1.079e-05 | 1.524 |
| chr15:43571211 | rs1108462 | TGM7 | G>A | 50 | 15240 | 19.25 | 1.144e-05 | 1.874 |
| chr2:130438514 | rs115248949 | - | A>G | 34 | 9070 | 19.22 | 1.167e-05 | 2.116 |
| chr20:41386186 | rs78166616 | PTPRT | C>T | 24 | 5596 | 19.21 | 1.169e-05 | 2.41 |
| chr5:57769993 | rs115117927 | - | G>A | 41 | 11692 | 19.02 | 1.294e-05 | 1.982 |
| chr9:22206559 | rs9696092 | - | T>C | 488 | 234724 | 18.61 | 1.602e-05 | 1.323 |
| chr2:235400198 | rs115074467 | - | A>G | 104 | 38805 | 18.32 | 1.865e-05 | 1.558 |
| chr11:25173713 | rs7115116 | - | A>G | 182 | 132722 | 18.2 | 1.988e-05 | 0.7046 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr17:3617087 | rs2976227 | - | G>A | 72 | 8086 | 31.33 | 2.177e-08 | 1.939 |
| chr3:40194741 | rs75831532 | MYRIP | A>G | 59 | 6673 | 24.98 | 5.792e-07 | 1.918 |
| chr21:30758760 | rs7277179 | BACH1 | G>A | 75 | 9174 | 24.4 | 7.818e-07 | 1.778 |
| chr15:89026568 | rs11858314 | AC013489.1 | T>C | 71 | 8603 | 24.36 | 7.976e-07 | 1.804 |
| chr7:48176096 | rs75065679 | - | A>C | 53 | 5873 | 23.79 | 1.077e-06 | 1.953 |
| chr4:182297812 | rs75493120 | - | G>A | 160 | 49142 | 23.74 | 1.104e-06 | 0.671 |
| chr2:201333312 | rs1469957 | SPATS2L | C>T | 50 | 5471 | 23.48 | 1.261e-06 | 1.981 |
| chr11:33947725 | rs10836130 | - | T>C | 1037 | 199347 | 23.3 | 1.383e-06 | 1.237 |
| chr14:72811484 | rs2681727 | RGS6 | A>C | 981 | 187105 | 22.76 | 1.834e-06 | 1.234 |
| chr6:104869938 | rs156236 | - | T>C | 428 | 74489 | 22.69 | 1.899e-06 | 1.296 |
| chr7:2959172 | rs3735126 | CARD11 | G>A | 99 | 13280 | 22.56 | 2.037e-06 | 1.626 |
| chr3:187054392 | rs7652396 | - | A>G | 68 | 8277 | 22.54 | 2.06e-06 | 1.785 |
| chr6:127108920 | rs2021708 | - | A>G | 782 | 191581 | 22.42 | 2.191e-06 | 0.8065 |
| chr3:124905146 | rs6784701 | SLC12A8 | C>T | 56 | 6451 | 22.38 | 2.241e-06 | 1.883 |
| chr14:30848490 | rs1955768 | - | G>A | 417 | 72707 | 21.74 | 3.12e-06 | 1.291 |
| chr17:72307990 | rs61351092 | DNAI2 | C>A | 107 | 14740 | 21.69 | 3.202e-06 | 1.584 |
| chr12:19263673 | rs16915076 | - | A>G | 48 | 5265 | 21.56 | 3.427e-06 | 1.952 |
| chr6:104873990 | rs17065032 | - | T>C | 335 | 56556 | 21.51 | 3.522e-06 | 1.319 |
| chr14:104636584 | rs8013773 | KIF26A | G>A | 521 | 93283 | 21.44 | 3.656e-06 | 1.264 |
| chr7:2962293 | rs3735131 | CARD11 | C>G | 95 | 12777 | 21.37 | 3.793e-06 | 1.62 |
Associated Phenotypes ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| HP: 0009789 | Perianal abscess | 3/20 |
| HP: 0010447 | Anal fistula | 2/20 |