M34.9

Case	Control
193	460012

Case

Control

193

460012

Top SNP Information

Location	SNP	Gene	Ref>Alt	Alt in Case	Alt in Control	Chi-square	P-value	Odds Ratio
chr18:36205618	rs117924775	-	C>T	20	16440	25.11	5.417e-07	2.987
chr13:32690447	rs41526255	FRY	T>C	65	86780	24.71	6.648e-07	1.942
chr4:136631324	rs114008044	-	T>C	15	10777	24.59	7.081e-07	3.411
chr13:90407539	rs74108813	-	C>T	19	15542	24.27	8.367e-07	3.009
chr11:25693444	rs16914345	-	T>G	21	18114	23.9	1.017e-06	2.851
chr8:79629586	rs77219198	ZC2HC1A	C>T	22	19879	23.69	1.131e-06	2.782
chr6:761367	rs111869752	-	T>G	39	44490	23.3	1.388e-06	2.208
chr1:240203931	rs80195683	FMN2	T>G	44	198810	23.19	1.468e-06	0.4719
chr3:79064388	rs114259074	ROBO1	C>A	14	10050	23.04	1.584e-06	3.414
chr16:19693627	rs117014682	VPS35L	C>T	26	25947	21.93	2.827e-06	2.502
chr11:10555586	rs72859181	RNF141	C>G	15	11493	21.84	2.958e-06	3.201
chr2:17927266	rs72768644	SMC6	T>C	18	15292	21.8	3.024e-06	2.928
chr11:10614988	rs55676441	LYVE1	G>T	14	10540	21.17	4.204e-06	3.265
chr3:69656759	rs56227388	-	C>T	26	26275	21.04	4.496e-06	2.458
chr6:152566624	rs77858297	SYNE1	A>G	23	22091	20.89	4.859e-06	2.576
chr12:98169658	rs79016877	-	A>G	21	19420	20.81	5.078e-06	2.671
chr6:13279507	rs3817741	PHACTR1	G>A	43	189322	20.62	5.598e-06	0.4883
chr20:9969480	rs6077623	ANKEF1	C>T	70	101424	20.62	5.615e-06	1.802
chr22:37025927	rs76021452	CACNG2	G>A	23	22467	20.59	5.683e-06	2.56
chr4:93323399	rs13106359	GRID2	G>T	26	26687	20.45	6.136e-06	2.429

Associated Phenotypes ^ⓘ

ID	Name	Top Correlation
HP: 0030873	Anticentromere antibody positivity	16/20

Name

Top Correlation

16/20

ID	Name	Top Correlation
HP: 0000118	Phenotypic abnormality	0/20
HP: 0000951	Abnormality of the skin	0/20
HP: 0001072	Thickened skin	0/20
HP: 0001574	Abnormality of the integument	0/20
HP: 0001626	Abnormality of the cardiovascular system	0/20
HP: 0002086	Abnormality of the respiratory system	0/20
HP: 0002088	Abnormal lung morphology	0/20
HP: 0002206	Pulmonary fibrosis	0/20
HP: 0002597	Abnormality of the vasculature	0/20
HP: 0002715	Abnormality of the immune system	0/20
HP: 0002960	Autoimmunity	0/20
HP: 0010978	Abnormality of immune system physiology	0/20
HP: 0011025	Abnormal cardiovascular system physiology	0/20
HP: 0011121	Abnormality of skin morphology	0/20
HP: 0011355	Localized skin lesion	0/20
HP: 0011838	Sclerodactyly	0/20
HP: 0012252	Abnormal respiratory system morphology	0/20
HP: 0012344	Morphea	0/20
HP: 0025323	Abnormal arterial physiology	0/20
HP: 0030057	Autoimmune antibody positivity	0/20
HP: 0030163	Abnormal vascular physiology	0/20
HP: 0030859	Topoisomerase I antibody positivity	0/20
HP: 0030880	Raynaud phenomenon	0/20
HP: 0031293	Digital pitting scar	0/20
HP: 0031917	Digital ulcer	0/20
HP: 0100276	Skin pit	0/20
HP: 0100324	Scleroderma	0/20
HP: 0200042	Skin ulcer	0/20
HP: 0550003	Proximal scleroderma	0/20
HP: 0550005	Bilateral basilar pulmonary fibrosis	0/20

Name

Top Correlation

0/20

0/20

0/20