Home
About
Help
ICD-10
HPO
Compare GWAS
Super Class
Other inflammatory spondylopathies
Sub Class
Inflammatory spondylopathy, unspecified (Cervical region)
Inflammatory spondylopathy, unspecified (Lumbar region)
Inflammatory spondylopathy, unspecified (Site unspecified)
Inflammatory spondylopathy, unspecified
M46.9
Case/Control GWAS
ⓘ
Links
Sex Split
Interactive Plot
Statistics
Case
Control
1522
458683
Top SNP Information
Show Table
Location
SNP
Gene
Ref>Alt
Alt in Case
Alt in Control
Chi-square
P-value
Odds Ratio
chr7:7350418
rs35221806
-
G>C
218
46825
25.19
5.183e-07
1.42
chr14:105347422
rs75678011
CEP170B
G>T
87
15457
24.41
7.789e-07
1.703
chr10:25983382
rs4749061
-
A>G
648
162668
23.89
1.018e-06
1.239
chr14:97847371
rs115524374
-
C>T
68
11443
23.09
1.543e-06
1.79
chr5:99764230
rs114179856
-
A>C
75
13009
23.02
1.607e-06
1.742
chr17:5743179
rs73977526
AC007846.2
A>G
99
18461
22.79
1.808e-06
1.622
chr4:139462203
rs17050483
-
C>A
156
32189
22.41
2.2e-06
1.473
chr11:25731449
rs11028856
-
A>C
108
49555
21.7
3.18e-06
0.636
chr4:166750013
rs115556111
-
G>A
119
23393
21.63
3.315e-06
1.54
chr5:171475689
rs10035578
STK10
T>G
956
251061
21.54
3.461e-06
1.196
chr1:205052939
rs4950979
TMEM81
A>G
552
138202
20.17
7.076e-06
1.233
chr14:105359077
rs117364891
CEP170B
C>T
87
16256
19.86
8.326e-06
1.618
chr9:18625666
rs79438518
ADAMTSL1
T>A
57
9506
19.72
8.946e-06
1.799
chr22:23934184
rs7285781
-
T>C
259
59634
19.51
9.984e-06
1.331
chr2:211567425
rs78065004
-
C>T
163
68049
19.51
9.995e-06
0.7021
chr5:78391629
rs13187410
DMGDH
A>T
74
13362
19.33
1.1e-05
1.67
chr17:50513725
rs12450868
-
G>C
89
16798
19.32
1.107e-05
1.599
chr4:140741251
rs62322634
MAML3
C>T
120
24191
19.14
1.212e-05
1.5
chr4:27218939
rs17591786
-
A>G
1100
365522
19.02
1.294e-05
0.8506
chr4:177310481
rs17631173
-
G>A
794
207126
18.89
1.387e-05
1.194
Associated Phenotypes
ⓘ
Shared SNP phenotypes
No shared SNP phenotypes
ID
Name
Top Correlation
HP: 0002946
Supernumerary vertebrae
2/20
HP: 0002948
Vertebral fusion
2/20
HP: 0003301
Irregular vertebral endplates
2/20
HP: 0003414
Atlantoaxial dislocation
2/20
HP: 0004557
Anterior vertebral fusion
3/20
HP: 0008416
Six lumbar vertebrae
1/20
HP: 0009144
Supernumerary bones of the axial skeleton
2/20
HP: 0030125
Sacralization of the fifth lumbar vertebra
3/20
HP: 0030304
Abnormal number of vertebrae
2/20
ID
Name
Top Correlation
HP: 0000118
Phenotypic abnormality
0/20
HP: 0000152
Abnormality of head or neck
0/20
HP: 0000234
Abnormality of the head
0/20
HP: 0000271
Abnormality of the face
0/20
HP: 0000478
Abnormality of the eye
0/20
HP: 0000553
Abnormal uvea morphology
0/20
HP: 0000554
Uveitis
0/20
HP: 0000707
Abnormality of the nervous system
0/20
HP: 0000765
Abnormality of the thorax
0/20
HP: 0000924
Abnormality of the skeletal system
0/20
HP: 0000925
Abnormality of the vertebral column
0/20
HP: 0000969
Edema
0/20
HP: 0001367
Abnormal joint morphology
0/20
HP: 0001369
Arthritis
0/20
HP: 0001376
Limitation of joint mobility
0/20
HP: 0001939
Abnormality of metabolism/homeostasis
0/20
HP: 0002011
Morphological central nervous system abnormality
0/20
HP: 0002143
Abnormality of the spinal cord
0/20
HP: 0002644
Abnormality of pelvic girdle bone morphology
0/20
HP: 0002715
Abnormality of the immune system
0/20
HP: 0002758
Osteoarthritis
0/20
HP: 0002808
Kyphosis
0/20
HP: 0002813
Abnormality of limb bone morphology
0/20
HP: 0002814
Abnormality of the lower limb
0/20
HP: 0002867
Abnormality of the ilium
0/20
HP: 0002942
Thoracic kyphosis
0/20
HP: 0003272
Abnormality of the hip bone
0/20
HP: 0003302
Spondylolisthesis
0/20
HP: 0003312
Abnormal form of the vertebral bodies
0/20
HP: 0003330
Abnormal bone structure
0/20
HP: 0003413
Atlantoaxial abnormality
0/20
HP: 0003416
Spinal canal stenosis
0/20
HP: 0003422
Vertebral segmentation defect
0/20
HP: 0003468
Abnormal vertebral morphology
0/20
HP: 0003549
Abnormality of connective tissue
0/20
HP: 0004576
Sclerotic vertebral endplates
0/20
HP: 0004610
Lumbar spinal canal stenosis
0/20
HP: 0005106
Abnormality of the vertebral endplates
0/20
HP: 0005107
Abnormal sacrum morphology
0/20
HP: 0005262
Abnormality of the synovia
0/20
HP: 0005619
Thoracolumbar kyphosis
0/20
HP: 0009121
Abnormal axial skeleton morphology
0/20
HP: 0010674
Abnormality of the curvature of the vertebral column
0/20
HP: 0010741
Pedal edema
0/20
HP: 0010978
Abnormality of immune system physiology
0/20
HP: 0011032
Abnormality of fluid regulation
0/20
HP: 0011729
Abnormality of joint mobility
0/20
HP: 0011842
Abnormality of skeletal morphology
0/20
HP: 0011843
Abnormality of skeletal physiology
0/20
HP: 0011844
Abnormal appendicular skeleton morphology
0/20
HP: 0012098
Edema of the dorsum of feet
0/20
HP: 0012122
Anterior uveitis
0/20
HP: 0012317
Sacroiliac arthritis
0/20
HP: 0012337
Abnormal homeostasis
0/20
HP: 0012372
Abnormal eye morphology
0/20
HP: 0012373
Abnormal eye physiology
0/20
HP: 0012639
Abnormal nervous system morphology
0/20
HP: 0012647
Abnormal inflammatory response
0/20
HP: 0012649
Increased inflammatory response
0/20
HP: 0031013
Ankylosis
0/20
HP: 0040064
Abnormality of limbs
0/20
HP: 0040068
Abnormality of limb bone
0/20
HP: 0040069
Abnormal lower limb bone morphology
0/20
HP: 0040313
Oligoarthritis
0/20
HP: 0100240
Synostosis of joints
0/20
HP: 0100533
Inflammatory abnormality of the eye
0/20
HP: 0100685
Abnormal Sharpey fiber morphology
0/20
HP: 0100686
Enthesitis
0/20
HP: 0100711
Abnormality of the thoracic spine
0/20
HP: 0100712
Abnormality of the lumbar spine
0/20
HP: 0100781
Abnormality of the sacroiliac joint
0/20