Statistics
| Female Case | Female Control | % Female |
|---|---|---|
| 556 | 249301 | 96% |
| Male Case | Male Control | % Male |
|---|---|---|
| 22 | 210315 | 4% |
Top SNP Information
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr12:68426205 | rs2108573 | - | T>C | 67 | 15189 | 30.51 | 3.318e-08 | 1.982 |
| chr2:144172700 | rs2381435 | ARHGAP15 | T>A | 290 | 98968 | 24.27 | 8.36e-07 | 1.393 |
| chr3:195661523 | rs114609331 | - | A>G | 33 | 6330 | 24.26 | 8.431e-07 | 2.331 |
| chr11:130115746 | rs12364607 | ZBTB44 | G>A | 152 | 45960 | 23.55 | 1.217e-06 | 1.52 |
| chr8:138476624 | rs77709125 | - | G>A | 79 | 20491 | 23.48 | 1.26e-06 | 1.747 |
| chr3:146087201 | rs74500645 | - | C>A | 44 | 9609 | 22.94 | 1.669e-06 | 2.058 |
| chr2:165298396 | rs74458848 | - | G>C | 36 | 7375 | 22.4 | 2.209e-06 | 2.188 |
| chr17:45811915 | rs190627217 | TBX21 | T>C | 49 | 11195 | 22.12 | 2.561e-06 | 1.963 |
| chr11:12155118 | rs57899657 | MICAL2 | G>C | 46 | 10315 | 22.03 | 2.685e-06 | 2.0 |
| chr9:36825946 | rs11794134 | - | G>A | 71 | 18236 | 21.75 | 3.109e-06 | 1.758 |
| chr11:85905715 | rs10792837 | - | A>G | 187 | 62503 | 20.95 | 4.722e-06 | 1.444 |
| chr5:60827094 | rs115226967 | ZSWIM6 | G>A | 29 | 5646 | 20.46 | 6.086e-06 | 2.29 |
| chr20:19803886 | rs6136849 | RIN2 | A>G | 347 | 185130 | 20.31 | 6.594e-06 | 0.751 |
| chr9:33177828 | rs62544390 | - | G>A | 103 | 29430 | 20.25 | 6.782e-06 | 1.585 |
| chr3:64475710 | rs9841181 | - | A>G | 45 | 10296 | 20.23 | 6.861e-06 | 1.959 |
| chr1:239770140 | rs6429144 | CHRM3 | C>T | 362 | 130053 | 19.81 | 8.541e-06 | 1.322 |
| chr3:61042288 | rs78758586 | FHIT | T>C | 72 | 19101 | 19.6 | 9.534e-06 | 1.704 |
| chr6:156162827 | rs35766481 | - | T>C | 63 | 48409 | 19.38 | 1.073e-05 | 0.5684 |
| chr4:164710968 | rs143786057 | MARCHF1 | T>C | 29 | 5800 | 19.21 | 1.173e-05 | 2.235 |
| chr1:38922053 | rs2251803 | - | A>G | 535 | 203201 | 19.08 | 1.255e-05 | 1.289 |
| Location | SNP | Gene | Ref>Alt | Alt in Case | Alt in Control | Chi-square | P-value | Odds ratio |
|---|---|---|---|---|---|---|---|---|
| chr16:82584726 | rs11864411 | - | A>C | 11 | 16158 | 48.42 | 3.445e-12 | 7.514 |
| chr2:164187390 | rs80193382 | - | C>T | 7 | 7379 | 46.71 | 8.218e-12 | 9.663 |
| chr16:24360519 | rs9925741 | CACNG3 | T>C | 8 | 9630 | 45.33 | 1.664e-11 | 8.635 |
| chr4:33498671 | rs73820671 | - | T>C | 7 | 8455 | 41.54 | 1.155e-10 | 8.84 |
| chr5:168991067 | rs73310469 | - | G>A | 8 | 10376 | 40.96 | 1.554e-10 | 7.974 |
| chr8:129203939 | rs186396656 | - | A>G | 5 | 4463 | 40.9 | 1.604e-10 | 11.01 |
| chr10:113769725 | rs1421052 | - | T>C | 6 | 6238 | 40.34 | 2.131e-10 | 9.543 |
| chr11:10874540 | rs2232929 | ZBED5 | G>A | 5 | 4541 | 40.03 | 2.497e-10 | 10.81 |
| chr3:186959295 | rs28945068 | MASP1 | C>T | 7 | 8486 | 39.24 | 3.753e-10 | 8.404 |
| chr16:82601097 | rs141344623 | - | G>T | 9 | 13371 | 38.72 | 4.886e-10 | 7.11 |
| chr4:111753481 | rs78171883 | - | C>T | 7 | 8617 | 38.46 | 5.587e-10 | 8.273 |
| chr5:144352240 | rs13184368 | - | C>A | 7 | 8807 | 38.45 | 5.625e-10 | 8.315 |
| chr15:94509022 | rs77286760 | - | G>A | 7 | 8780 | 37.45 | 9.362e-10 | 8.103 |
| chr3:77719800 | rs79954885 | - | A>G | 11 | 19464 | 37.23 | 1.051e-09 | 6.179 |
| chr9:107844037 | rs113364927 | - | C>T | 10 | 17867 | 35.25 | 2.898e-09 | 6.296 |
| chr11:29696688 | rs11822885 | - | A>G | 9 | 14304 | 35.25 | 2.903e-09 | 6.628 |
| chr3:192323258 | rs74960852 | FGF12 | C>T | 6 | 7090 | 34.64 | 3.959e-09 | 8.448 |
| chr6:170602429 | rs17860704 | DLL1 | T>C | 5 | 5121 | 34.45 | 4.375e-09 | 9.558 |
| chr3:52834753 | rs2710333 | ITIH3 | A>G | 6 | 7135 | 33.34 | 7.743e-09 | 8.197 |
| chr1:96785327 | rs80071287 | - | A>G | 5 | 5268 | 33.32 | 7.811e-09 | 9.304 |
Associated Phenotypes ⓘ
| ID | Name | Top Correlation |
|---|---|---|
| HP: 0031109 | Agalactia | 13/20 |