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ICD-10
HPO
Compare GWAS
Super Class
Gestational [pregnancy-induced] hypertension with significant proteinuria
Sub Class
Moderate preeclampsia
O14.0
Case/Control GWAS
ⓘ
Links
Sex Split
Interactive Plot
Statistics
Case
Control
83
460123
Top SNP Information
Show Table
Location
SNP
Gene
Ref>Alt
Alt in Case
Alt in Control
Chi-square
P-value
Odds Ratio
chr7:113340067
rs7802710
-
A>G
20
12848
117.2
2.568e-27
8.411
chr8:141716284
rs10100025
PTK2
G>A
17
10105
109.9
1.005e-25
8.975
chr1:173579034
rs12065033
AL139142.2
C>T
20
15321
93.07
5.037e-22
7.041
chr17:29298304
rs7225888
RNF135
C>G
23
19912
92.02
8.573e-22
6.381
chr17:3553526
rs161350
CTNS
G>A
16
10480
91.38
1.188e-21
8.099
chr12:57843014
rs776037
INHBC
T>C
18
13475
86.18
1.647e-20
7.133
chr17:29290106
rs55861543
-
C>T
23
20736
85.55
2.259e-20
6.048
chr1:159174683
rs2814778
ACKR1
T>C
22
19355
84.8
3.309e-20
6.179
chr1:228633067
rs6679518
-
T>C
26
26431
81.26
1.982e-19
5.417
chr17:29350769
rs8073072
-
T>G
25
25681
77.69
1.202e-18
5.38
chr2:237204719
rs12329199
-
C>T
15
10726
77.33
1.449e-18
7.456
chr6:137325847
rs1555498
IL20RA
T>C
17
13320
76.57
2.123e-18
6.786
chr17:29268139
rs9907098
ADAP2
C>A
20
17895
74.93
4.882e-18
6.005
chr7:104111048
rs59299745
LHFPL3
C>G
15
11012
74.58
5.834e-18
7.253
chr5:83128858
rs7709612
-
A>G
15
11079
73.96
7.973e-18
7.208
chr19:52249900
rs5030879
FPR1
G>A
14
9840
73.72
9.015e-18
7.546
chr6:137344363
rs1744080
IL20RA
G>A
19
16592
73.33
1.099e-17
6.11
chr10:1411012
rs12762472
ADARB2
G>C
14
9875
73.31
1.109e-17
7.514
chr10:117649124
rs7904803
ATRNL1
C>A
19
18667
73.26
1.136e-17
6.19
chr12:53817956
rs784894
AMHR2
C>A
15
11089
72.81
1.425e-17
7.119
Associated Phenotypes
ⓘ
Shared SNP phenotypes
No shared SNP phenotypes
ID
Name
Top Correlation
HP: 0000079
Abnormality of the urinary system
2/20
HP: 0000119
Abnormality of the genitourinary system
2/20
HP: 0000479
Abnormal retinal morphology
4/20
HP: 0001095
Hypertensive retinopathy
6/20
HP: 0001098
Abnormal fundus morphology
1/20
HP: 0001194
Abnormalities of placenta or umbilical cord
3/20
HP: 0001197
Abnormality of prenatal development or birth
3/20
HP: 0001939
Abnormality of metabolism/homeostasis
2/20
HP: 0002500
Abnormality of the cerebral white matter
5/20
HP: 0002518
Abnormality of the periventricular white matter
2/20
HP: 0002686
Prenatal maternal abnormality
3/20
HP: 0003110
Abnormality of urine homeostasis
2/20
HP: 0004329
Abnormal posterior eye segment morphology
2/20
HP: 0004364
Abnormal circulating nitrogen compound concentration
2/20
HP: 0006970
Periventricular leukomalacia
20/20
HP: 0008047
Abnormality of the vasculature of the eye
2/20
HP: 0010993
Abnormality of the cerebral subcortex
6/20
HP: 0011277
Abnormality of the urinary system physiology
2/20
HP: 0011419
Placental abruption
1/20
HP: 0012597
Heavy proteinuria
11/20
HP: 0032180
Abnormal circulating metabolite concentration
2/20
HP: 0100601
Eclampsia
3/20
HP: 0100602
Preeclampsia
3/20
HP: 0100603
Toxemia of pregnancy
3/20
HP: 0100767
Abnormality of the placenta
2/20
ID
Name
Top Correlation
HP: 0000093
Proteinuria
0/20
HP: 0000118
Phenotypic abnormality
0/20
HP: 0000152
Abnormality of head or neck
0/20
HP: 0000234
Abnormality of the head
0/20
HP: 0000271
Abnormality of the face
0/20
HP: 0000478
Abnormality of the eye
0/20
HP: 0000707
Abnormality of the nervous system
0/20
HP: 0001626
Abnormality of the cardiovascular system
0/20
HP: 0002011
Morphological central nervous system abnormality
0/20
HP: 0002060
Abnormal cerebral morphology
0/20
HP: 0002180
Neurodegeneration
0/20
HP: 0002352
Leukoencephalopathy
0/20
HP: 0002597
Abnormality of the vasculature
0/20
HP: 0007367
Atrophy/Degeneration affecting the central nervous system
0/20
HP: 0008046
Abnormal retinal vascular morphology
0/20
HP: 0012372
Abnormal eye morphology
0/20
HP: 0012443
Abnormality of brain morphology
0/20
HP: 0012639
Abnormal nervous system morphology
0/20
HP: 0020129
Abnormal urine protein level
0/20
HP: 0100547
Abnormality of forebrain morphology
0/20