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ICD-10
HPO
Compare GWAS
Super Class
Premature rupture of membranes
Sub Class
Premature rupture of membranes, onset of labour after 24 hours
O42.1
Case/Control GWAS
ⓘ
Links
Sex Split
Interactive Plot
Statistics
Case
Control
300
459905
Top SNP Information
Show Table
Location
SNP
Gene
Ref>Alt
Alt in Case
Alt in Control
Chi-square
P-value
Odds Ratio
chr13:108364208
rs74112579
FAM155A
G>C
30
13954
43.87
3.503e-11
3.225
chr5:39249206
rs835194
FYB1
G>A
44
26140
37.89
7.478e-10
2.527
chr5:177964645
rs10479497
COL23A1
C>T
25
11353
37.51
9.112e-10
3.255
chr2:242878225
rs10172398
-
G>A
45
27385
37.37
9.79e-10
2.49
chr12:121946793
rs80097692
KDM2B
A>G
25
11492
36.73
1.357e-09
3.218
chr8:108664948
rs4266623
-
G>T
25
11581
36.4
1.607e-09
3.203
chr6:170242949
rs9396958
-
T>C
31
16083
36.21
1.77e-09
2.88
chr9:137331106
rs14317
RXRA
C>A
38
21895
35.05
3.218e-09
2.593
chr19:49034011
rs12610714
-
A>G
58
40063
34.51
4.242e-09
2.197
chr9:38074715
rs1928251
-
T>C
47
30075
33.83
6.016e-09
2.35
chr9:128990977
rs16928801
-
G>A
34
18944
33.72
6.371e-09
2.672
chr7:78206401
rs28439811
MAGI2
C>A
40
23976
33.58
6.832e-09
2.493
chr8:120522589
rs1446067
-
G>A
33
18363
32.97
9.341e-09
2.68
chr9:38043419
rs73646139
AL138752.2
T>C
39
23124
32.73
1.06e-08
2.494
chr1:173579034
rs12065033
AL139142.2
C>T
29
15312
32.28
1.336e-08
2.809
chr1:20254356
rs7543354
-
C>T
22
10159
31.97
1.564e-08
3.192
chr5:148175047
rs9325117
-
A>G
32
17870
31.56
1.932e-08
2.661
chr12:101754703
rs10219562
UTP20
T>C
55
38332
31.4
2.095e-08
2.159
chr2:137797262
rs16837912
THSD7B
A>C
30
16391
31.03
2.545e-08
2.716
chr7:3737407
rs73302247
SDK1
C>T
75
58642
30.82
2.824e-08
1.95
Associated Phenotypes
ⓘ
Shared SNP phenotypes
No shared SNP phenotypes
ID
Name
Top Correlation
HP: 0000008
Abnormal morphology of female internal genitalia
1/20
HP: 0000118
Phenotypic abnormality
1/20
HP: 0000130
Abnormality of the uterus
1/20
HP: 0000812
Abnormal internal genitalia
1/20
HP: 0001194
Abnormalities of placenta or umbilical cord
1/20
HP: 0001197
Abnormality of prenatal development or birth
2/20
HP: 0001560
Abnormality of the amniotic fluid
2/20
HP: 0001562
Oligohydramnios
2/20
HP: 0001622
Premature birth
2/20
HP: 0001626
Abnormality of the cardiovascular system
1/20
HP: 0001787
Abnormal delivery
2/20
HP: 0001788
Premature rupture of membranes
2/20
HP: 0001945
Fever
1/20
HP: 0002686
Prenatal maternal abnormality
2/20
HP: 0002715
Abnormality of the immune system
1/20
HP: 0004370
Abnormality of temperature regulation
1/20
HP: 0010978
Abnormality of immune system physiology
1/20
HP: 0011419
Placental abruption
1/20
HP: 0012337
Abnormal homeostasis
1/20
HP: 0025328
Antepartum hemorrhage
2/20
HP: 0030009
Cervical insufficiency
2/20
HP: 0030244
Maternal fever in pregnancy
1/20
HP: 0030245
Intrapartum fever
1/20
HP: 0030917
Low APGAR score
2/20
HP: 0030918
Low 1-minute APGAR score
2/20
HP: 0030927
1-minute APGAR score of 0
1/20
HP: 0100767
Abnormality of the placenta
1/20
ID
Name
Top Correlation
HP: 0000078
Abnormality of the genital system
0/20
HP: 0000119
Abnormality of the genitourinary system
0/20
HP: 0001871
Abnormality of blood and blood-forming tissues
0/20
HP: 0001892
Abnormal bleeding
0/20
HP: 0001939
Abnormality of metabolism/homeostasis
0/20
HP: 0010460
Abnormality of the female genitalia
0/20
HP: 0011025
Abnormal cardiovascular system physiology
0/20
HP: 0011028
Abnormality of blood circulation
0/20
HP: 0011029
Internal hemorrhage
0/20
HP: 0012243
Abnormal reproductive system morphology
0/20
HP: 0012888
Abnormality of the uterine cervix
0/20
HP: 0040187
Neonatal sepsis
0/20
HP: 0100806
Sepsis
0/20