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ICD-10
HPO
Compare GWAS
Super Class
Symptoms and signs involving the circulatory and respiratory systems
Sub Class
Pain in throat
Chest pain on breathing
Precordial pain
Other chest pain
Chest pain, unspecified
Pain in throat and chest
R07
Case/Control GWAS
ⓘ
Links
Sex Split
Interactive Plot
Statistics
Case
Control
39712
420482
Top SNP Information
Show Table
Location
SNP
Gene
Ref>Alt
Alt in Case
Alt in Control
Chi-square
P-value
Odds Ratio
chr5:33951693
rs16891982
SLC45A2
G>C
7298
59763
378.2
3.126e-84
1.286
chr5:33958959
rs28777
SLC45A2
A>C
6220
50775
327.7
3.039e-73
1.286
chr5:33955673
rs35391
SLC45A2
C>T
4463
36519
226.4
3.687e-51
1.277
chr5:33955326
rs35390
SLC45A2
A>C
4476
36673
224.6
9.134e-51
1.275
chr5:33951116
rs35397
SLC45A2
T>G
9151
80960
219.8
9.972e-50
1.188
chr2:66725070
rs12995572
MEIS1
G>C
3017
24134
181.7
2.013e-41
1.302
chr11:61095368
rs7397033
DDB1
T>C
1770
13156
173.3
1.396e-39
1.398
chr16:28954860
rs7203982
-
T>C
3206
26176
163.3
2.153e-37
1.275
chr16:28995057
rs11859822
SPNS1
T>C
3210
26226
162.5
3.182e-37
1.274
chr9:129562274
rs78594581
-
C>T
1623
12256
144.5
2.712e-33
1.376
chr11:61108974
rs2260655
DDB1
A>G
2319
18566
137.6
8.847e-32
1.298
chr6:100241479
rs9495569
-
A>G
2498
20205
137.0
1.214e-31
1.286
chr6:136480972
rs9483910
PDE7B
C>T
2361
19011
134.4
4.545e-31
1.291
chr19:42393286
rs717225
ARHGEF1
A>G
2416
19527
133.4
7.324e-31
1.287
chr1:31907102
rs7417775
SERINC2
G>A
4097
35144
132.7
1.073e-30
1.215
chr1:159174683
rs2814778
ACKR1
T>C
2157
17220
130.7
2.909e-30
1.302
chr11:61063156
rs10897150
-
T>G
2710
22266
130.6
3.023e-30
1.266
chr16:129223
rs710079
MPG
C>T
3007
25037
129.5
5.333e-30
1.25
chr17:5865515
rs723656
AC007846.2
G>A
3947
33850
128.0
1.125e-29
1.215
chr11:61144707
rs1377458
-
T>C
2170
17421
125.4
4.195e-29
1.294
Associated Phenotypes
ⓘ
Shared SNP phenotypes
No shared SNP phenotypes
ID
Name
Top Correlation
HP: 0000118
Phenotypic abnormality
1/20
HP: 0000600
Abnormality of the pharynx
1/20
HP: 0000756
Agoraphobia
3/20
HP: 0000765
Abnormality of the thorax
1/20
HP: 0001627
Abnormal heart morphology
4/20
HP: 0001739
Abnormality of the nasopharynx
3/20
HP: 0001939
Abnormality of metabolism/homeostasis
2/20
HP: 0001962
Palpitations
18/20
HP: 0002205
Recurrent respiratory infections
1/20
HP: 0002788
Recurrent upper respiratory tract infections
3/20
HP: 0003115
Abnormal EKG
2/20
HP: 0003140
T-wave inversion in the right precordial leads
2/20
HP: 0005120
Abnormal cardiac atrium morphology
3/20
HP: 0011025
Abnormal cardiovascular system physiology
1/20
HP: 0011110
Tonsillitis
1/20
HP: 0011628
Congenital defect of the pericardium
7/20
HP: 0011629
Total absence of the pericardium
7/20
HP: 0011642
Abnormal coronary sinus morphology
3/20
HP: 0012249
Abnormal ST segment
5/20
HP: 0012250
ST segment depression
5/20
HP: 0012251
ST segment elevation
8/20
HP: 0012337
Abnormal homeostasis
13/20
HP: 0012735
Cough
2/20
HP: 0025015
Abnormal vascular morphology
2/20
HP: 0025143
Chills
5/20
HP: 0025323
Abnormal arterial physiology
5/20
HP: 0025439
Pharyngitis
1/20
HP: 0025496
Abnormal coronary artery physiology
7/20
HP: 0025497
Coronary artery spasm
7/20
HP: 0030766
Ear pain
3/20
HP: 0030846
Abnormality of venous physiology
1/20
HP: 0030847
Abnormal jugular venous pressure
2/20
HP: 0030848
Elevated jugular venous pressure
2/20
HP: 0031298
Coronary sinus enlargement
3/20
HP: 0031659
Fourth heart sound
2/20
HP: 0031690
Opportunistic infection
3/20
HP: 0032141
Precordial pain
1/20
HP: 0032249
Coccidioidomycosis
2/20
HP: 0100749
Chest pain
6/20
HP: 0100763
Abnormality of the lymphatic system
1/20
HP: 0100776
Recurrent pharyngitis
7/20
HP: 0100851
Abnormal emotion/affect behavior
3/20
HP: 0100852
Abnormal fear/anxiety-related behavior
2/20
HP: 0500015
Abnormal cardiac test
2/20
ID
Name
Top Correlation
HP: 0000152
Abnormality of head or neck
0/20
HP: 0000234
Abnormality of the head
0/20
HP: 0000271
Abnormality of the face
0/20
HP: 0000366
Abnormality of the nose
0/20
HP: 0000598
Abnormality of the ear
0/20
HP: 0000707
Abnormality of the nervous system
0/20
HP: 0000708
Behavioral abnormality
0/20
HP: 0000924
Abnormality of the skeletal system
0/20
HP: 0000969
Edema
0/20
HP: 0001608
Abnormality of the voice
0/20
HP: 0001609
Hoarse voice
0/20
HP: 0001626
Abnormality of the cardiovascular system
0/20
HP: 0001697
Abnormal pericardium morphology
0/20
HP: 0002012
Abnormality of the abdominal organs
0/20
HP: 0002086
Abnormality of the respiratory system
0/20
HP: 0002088
Abnormal lung morphology
0/20
HP: 0002105
Hemoptysis
0/20
HP: 0002597
Abnormality of the vasculature
0/20
HP: 0002715
Abnormality of the immune system
0/20
HP: 0002719
Recurrent infections
0/20
HP: 0002795
Functional respiratory abnormality
0/20
HP: 0003565
Elevated erythrocyte sedimentation rate
0/20
HP: 0005135
Abnormal T-wave
0/20
HP: 0009121
Abnormal axial skeleton morphology
0/20
HP: 0010872
T-wave inversion
0/20
HP: 0010978
Abnormality of immune system physiology
0/20
HP: 0011024
Abnormality of the gastrointestinal tract
0/20
HP: 0011032
Abnormality of fluid regulation
0/20
HP: 0011675
Arrhythmia
0/20
HP: 0011842
Abnormality of skeletal morphology
0/20
HP: 0011855
Pharyngeal edema
0/20
HP: 0011947
Respiratory tract infection
0/20
HP: 0012252
Abnormal respiratory system morphology
0/20
HP: 0012531
Pain
0/20
HP: 0012638
Abnormal nervous system physiology
0/20
HP: 0012719
Functional abnormality of the gastrointestinal tract
0/20
HP: 0020100
Unusual fungal infection
0/20
HP: 0025021
Abnormal erythrocyte sedimentation rate
0/20
HP: 0025031
Abnormality of the digestive system
0/20
HP: 0025032
Abnormality of digestive system physiology
0/20
HP: 0025033
Abnormality of digestive system morphology
0/20
HP: 0025142
Constitutional symptom
0/20
HP: 0030163
Abnormal vascular physiology
0/20
HP: 0030166
Night sweats
0/20
HP: 0030680
Abnormality of cardiovascular system morphology
0/20
HP: 0030956
Abnormality of cardiovascular system electrophysiology
0/20
HP: 0031245
Productive cough
0/20
HP: 0031416
Abnormal nasal mucus secretion
0/20
HP: 0031417
Rhinorrhea
0/20
HP: 0031466
Impairment in personality functioning
0/20
HP: 0031657
Abnormal heart sound
0/20
HP: 0031704
Abnormal ear physiology
0/20
HP: 0032016
Abnormal sputum
0/20
HP: 0032043
Odynophagia
0/20
HP: 0032101
Unusual infection
0/20
HP: 0032255
Opportunistic fungal infection
0/20
HP: 0100765
Abnormality of the tonsils
0/20